Aspirin in Patients With Previous Percutaneous Coronary Intervention Undergoing Noncardiac Surgery.
Identifieur interne : 001166 ( Main/Exploration ); précédent : 001165; suivant : 001167Aspirin in Patients With Previous Percutaneous Coronary Intervention Undergoing Noncardiac Surgery.
Auteurs : Michelle M. Graham [France] ; Daniel I. Sessler [France] ; Joel L. Parlow [France] ; Bruce M. Biccard [France] ; Gordon Guyatt [France] ; Kate Leslie [France] ; Matthew T V. Chan [France] ; Christian S. Meyhoff [France] ; Denis Xavier [France] ; Alben Sigamani [France] ; Priya A. Kumar [France] ; Marko Mrkobrada [France] ; Deborah J. Cook [France] ; Vikas Tandon [France] ; Jesus Alvarez-Garcia [France] ; Juan Carlos Villar [France] ; Thomas W. Painter [France] ; Giovanni Landoni [France] ; Edith Fleischmann [France] ; Andre Lamy [France] ; Richard Whitlock [France] ; Yannick Le Manach [France] ; Meylin Aphang-Lam [France] ; Juan P. Cata [France] ; Peggy Gao [France] ; Nicolaas C S. Terblanche [France] ; Pamidimukkala V. Ramana [France] ; Kim A. Jamieson [France] ; Amal Bessissow [France] ; Gabriela R. Mendoza [France] ; Silvia Ramirez [France] ; Pierre A. Diemunsch [France] ; Salim Yusuf [France] ; P J Devereaux [France]Source :
- Annals of internal medicine [ 1539-3704 ] ; 2017.
Abstract
Uncertainty remains about the effects of aspirin in patients with prior percutaneous coronary intervention (PCI) having noncardiac surgery.
DOI: 10.7326/M17-2341
PubMed: 29132159
Affiliations:
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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Aspirin in Patients With Previous Percutaneous Coronary Intervention Undergoing Noncardiac Surgery.</title><author><name sortKey="Graham, Michelle M" sort="Graham, Michelle M" uniqKey="Graham M" first="Michelle M" last="Graham">Michelle M. Graham</name><affiliation wicri:level="3"><nlm:affiliation>From University of Alberta and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Cleveland Clinic, Cleveland, Ohio; Queen's University, Kingston, Ontario, Canada; Groote Schuur Hospital and University of Cape Town, Western Cape, South Africa; Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada; Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, and Monash University, Melbourne, Victoria, Australia; The Chinese University of Hong Kong, Hong Kong, China; Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; St. John's Medical College and Research Institute, Bangalore, India; Narayana Hrudayalaya, Bangalore, India; University of North Carolina, Chapel Hill, North Carolina; Schulich School of Medicine & Dentistry at Western University, London, Ontario, Canada; Sant Pau Hospital and Biomedical Research Institute, Autonomous University of Barcelona, Research Center of Cardiovascular Diseases (CIBERCV), Barcelona, Spain; Fundación Cardioinfantil Instituto de Cardiología, Bogotá, and Universidad Autónoma de Bucaramanga, Santander, Colombia; University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy; Medical University of Vienna, Vienna, Austria; Hospital Arzobispo Loayza, Universidad Peruana Cayetano Heredia, Lima, Peru; The University of Texas MD Anderson Cancer Center, Houston, Texas; Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia; CARE Hospitals, Maharanipeta, Visakhapatnam, India; Auckland City Hospital, Auckland, New Zealand; McGill University Health Centre, Montréal, Québec, Canada; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Universitario Fundación Hospital Alcorcon, Madrid, Spain; and Centre Hospitalier Universitaire de Hautepierre, Strasbourg, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>From University of Alberta and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Cleveland Clinic, Cleveland, Ohio; Queen's University, Kingston, Ontario, Canada; Groote Schuur Hospital and University of Cape Town, Western Cape, South Africa; Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada; Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, and Monash University, Melbourne, Victoria, Australia; The Chinese University of Hong Kong, Hong Kong, China; Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; St. John's Medical College and Research Institute, Bangalore, India; Narayana Hrudayalaya, Bangalore, India; University of North Carolina, Chapel Hill, North Carolina; Schulich School of Medicine & Dentistry at Western University, London, Ontario, Canada; Sant Pau Hospital and Biomedical Research Institute, Autonomous University of Barcelona, Research Center of Cardiovascular Diseases (CIBERCV), Barcelona, Spain; Fundación Cardioinfantil Instituto de Cardiología, Bogotá, and Universidad Autónoma de Bucaramanga, Santander, Colombia; University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy; Medical University of Vienna, Vienna, Austria; Hospital Arzobispo Loayza, Universidad Peruana Cayetano Heredia, Lima, Peru; The University of Texas MD Anderson Cancer Center, Houston, Texas; Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia; CARE Hospitals, Maharanipeta, Visakhapatnam, India; Auckland City Hospital, Auckland, New Zealand; McGill University Health Centre, Montréal, Québec, Canada; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Universitario Fundación Hospital Alcorcon, Madrid, Spain; and Centre Hospitalier Universitaire de Hautepierre, Strasbourg</wicri:regionArea><placeName><region type="region">Grand Est</region><region type="old region">Alsace (région administrative)</region><settlement type="city">Strasbourg</settlement></placeName></affiliation></author><author><name sortKey="Sessler, Daniel I" sort="Sessler, Daniel I" uniqKey="Sessler D" first="Daniel I" last="Sessler">Daniel I. Sessler</name><affiliation wicri:level="3"><nlm:affiliation>From University of Alberta and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Cleveland Clinic, Cleveland, Ohio; Queen's University, Kingston, Ontario, Canada; Groote Schuur Hospital and University of Cape Town, Western Cape, South Africa; Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada; Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, and Monash University, Melbourne, Victoria, Australia; The Chinese University of Hong Kong, Hong Kong, China; Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; St. John's Medical College and Research Institute, Bangalore, India; Narayana Hrudayalaya, Bangalore, India; University of North Carolina, Chapel Hill, North Carolina; Schulich School of Medicine & Dentistry at Western University, London, Ontario, Canada; Sant Pau Hospital and Biomedical Research Institute, Autonomous University of Barcelona, Research Center of Cardiovascular Diseases (CIBERCV), Barcelona, Spain; Fundación Cardioinfantil Instituto de Cardiología, Bogotá, and Universidad Autónoma de Bucaramanga, Santander, Colombia; University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy; Medical University of Vienna, Vienna, Austria; Hospital Arzobispo Loayza, Universidad Peruana Cayetano Heredia, Lima, Peru; The University of Texas MD Anderson Cancer Center, Houston, Texas; Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia; CARE Hospitals, Maharanipeta, Visakhapatnam, India; Auckland City Hospital, Auckland, New Zealand; McGill University Health Centre, Montréal, Québec, Canada; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Universitario Fundación Hospital Alcorcon, Madrid, Spain; and Centre Hospitalier Universitaire de Hautepierre, Strasbourg, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>From University of Alberta and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Cleveland Clinic, Cleveland, Ohio; Queen's University, Kingston, Ontario, Canada; Groote Schuur Hospital and University of Cape Town, Western Cape, South Africa; Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada; Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, and Monash University, Melbourne, Victoria, Australia; The Chinese University of Hong Kong, Hong Kong, China; Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; St. John's Medical College and Research Institute, Bangalore, India; Narayana Hrudayalaya, Bangalore, India; University of North Carolina, Chapel Hill, North Carolina; Schulich School of Medicine & Dentistry at Western University, London, Ontario, Canada; Sant Pau Hospital and Biomedical Research Institute, Autonomous University of Barcelona, Research Center of Cardiovascular Diseases (CIBERCV), Barcelona, Spain; Fundación Cardioinfantil Instituto de Cardiología, Bogotá, and Universidad Autónoma de Bucaramanga, Santander, Colombia; University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy; Medical University of Vienna, Vienna, Austria; Hospital Arzobispo Loayza, Universidad Peruana Cayetano Heredia, Lima, Peru; The University of Texas MD Anderson Cancer Center, Houston, Texas; Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia; CARE Hospitals, Maharanipeta, Visakhapatnam, India; Auckland City Hospital, Auckland, New Zealand; McGill University Health Centre, Montréal, Québec, Canada; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Universitario Fundación Hospital Alcorcon, Madrid, Spain; and Centre Hospitalier Universitaire de Hautepierre, Strasbourg</wicri:regionArea><placeName><region type="region">Grand Est</region><region type="old region">Alsace (région administrative)</region><settlement type="city">Strasbourg</settlement></placeName></affiliation></author><author><name sortKey="Parlow, Joel L" sort="Parlow, Joel L" uniqKey="Parlow J" first="Joel L" last="Parlow">Joel L. Parlow</name><affiliation wicri:level="3"><nlm:affiliation>From University of Alberta and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Cleveland Clinic, Cleveland, Ohio; Queen's University, Kingston, Ontario, Canada; Groote Schuur Hospital and University of Cape Town, Western Cape, South Africa; Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada; Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, and Monash University, Melbourne, Victoria, Australia; The Chinese University of Hong Kong, Hong Kong, China; Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; St. John's Medical College and Research Institute, Bangalore, India; Narayana Hrudayalaya, Bangalore, India; University of North Carolina, Chapel Hill, North Carolina; Schulich School of Medicine & Dentistry at Western University, London, Ontario, Canada; Sant Pau Hospital and Biomedical Research Institute, Autonomous University of Barcelona, Research Center of Cardiovascular Diseases (CIBERCV), Barcelona, Spain; Fundación Cardioinfantil Instituto de Cardiología, Bogotá, and Universidad Autónoma de Bucaramanga, Santander, Colombia; University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy; Medical University of Vienna, Vienna, Austria; Hospital Arzobispo Loayza, Universidad Peruana Cayetano Heredia, Lima, Peru; The University of Texas MD Anderson Cancer Center, Houston, Texas; Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia; CARE Hospitals, Maharanipeta, Visakhapatnam, India; Auckland City Hospital, Auckland, New Zealand; McGill University Health Centre, Montréal, Québec, Canada; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Universitario Fundación Hospital Alcorcon, Madrid, Spain; and Centre Hospitalier Universitaire de Hautepierre, Strasbourg, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>From University of Alberta and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Cleveland Clinic, Cleveland, Ohio; Queen's University, Kingston, Ontario, Canada; Groote Schuur Hospital and University of Cape Town, Western Cape, South Africa; Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada; Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, and Monash University, Melbourne, Victoria, Australia; The Chinese University of Hong Kong, Hong Kong, China; Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; St. John's Medical College and Research Institute, Bangalore, India; Narayana Hrudayalaya, Bangalore, India; University of North Carolina, Chapel Hill, North Carolina; Schulich School of Medicine & Dentistry at Western University, London, Ontario, Canada; Sant Pau Hospital and Biomedical Research Institute, Autonomous University of Barcelona, Research Center of Cardiovascular Diseases (CIBERCV), Barcelona, Spain; Fundación Cardioinfantil Instituto de Cardiología, Bogotá, and Universidad Autónoma de Bucaramanga, Santander, Colombia; University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy; Medical University of Vienna, Vienna, Austria; Hospital Arzobispo Loayza, Universidad Peruana Cayetano Heredia, Lima, Peru; The University of Texas MD Anderson Cancer Center, Houston, Texas; Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia; CARE Hospitals, Maharanipeta, Visakhapatnam, India; Auckland City Hospital, Auckland, New Zealand; McGill University Health Centre, Montréal, Québec, Canada; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Universitario Fundación Hospital Alcorcon, Madrid, Spain; and Centre Hospitalier Universitaire de Hautepierre, Strasbourg</wicri:regionArea><placeName><region type="region">Grand Est</region><region type="old region">Alsace (région administrative)</region><settlement type="city">Strasbourg</settlement></placeName></affiliation></author><author><name sortKey="Biccard, Bruce M" sort="Biccard, Bruce M" uniqKey="Biccard B" first="Bruce M" last="Biccard">Bruce M. Biccard</name><affiliation wicri:level="3"><nlm:affiliation>From University of Alberta and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Cleveland Clinic, Cleveland, Ohio; Queen's University, Kingston, Ontario, Canada; Groote Schuur Hospital and University of Cape Town, Western Cape, South Africa; Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada; Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, and Monash University, Melbourne, Victoria, Australia; The Chinese University of Hong Kong, Hong Kong, China; Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; St. John's Medical College and Research Institute, Bangalore, India; Narayana Hrudayalaya, Bangalore, India; University of North Carolina, Chapel Hill, North Carolina; Schulich School of Medicine & Dentistry at Western University, London, Ontario, Canada; Sant Pau Hospital and Biomedical Research Institute, Autonomous University of Barcelona, Research Center of Cardiovascular Diseases (CIBERCV), Barcelona, Spain; Fundación Cardioinfantil Instituto de Cardiología, Bogotá, and Universidad Autónoma de Bucaramanga, Santander, Colombia; University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy; Medical University of Vienna, Vienna, Austria; Hospital Arzobispo Loayza, Universidad Peruana Cayetano Heredia, Lima, Peru; The University of Texas MD Anderson Cancer Center, Houston, Texas; Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia; CARE Hospitals, Maharanipeta, Visakhapatnam, India; Auckland City Hospital, Auckland, New Zealand; McGill University Health Centre, Montréal, Québec, Canada; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Universitario Fundación Hospital Alcorcon, Madrid, Spain; and Centre Hospitalier Universitaire de Hautepierre, Strasbourg, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>From University of Alberta and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Cleveland Clinic, Cleveland, Ohio; Queen's University, Kingston, Ontario, Canada; Groote Schuur Hospital and University of Cape Town, Western Cape, South Africa; Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada; Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, and Monash University, Melbourne, Victoria, Australia; The Chinese University of Hong Kong, Hong Kong, China; Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; St. John's Medical College and Research Institute, Bangalore, India; Narayana Hrudayalaya, Bangalore, India; University of North Carolina, Chapel Hill, North Carolina; Schulich School of Medicine & Dentistry at Western University, London, Ontario, Canada; Sant Pau Hospital and Biomedical Research Institute, Autonomous University of Barcelona, Research Center of Cardiovascular Diseases (CIBERCV), Barcelona, Spain; Fundación Cardioinfantil Instituto de Cardiología, Bogotá, and Universidad Autónoma de Bucaramanga, Santander, Colombia; University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy; Medical University of Vienna, Vienna, Austria; Hospital Arzobispo Loayza, Universidad Peruana Cayetano Heredia, Lima, Peru; The University of Texas MD Anderson Cancer Center, Houston, Texas; Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia; CARE Hospitals, Maharanipeta, Visakhapatnam, India; Auckland City Hospital, Auckland, New Zealand; McGill University Health Centre, Montréal, Québec, Canada; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Universitario Fundación Hospital Alcorcon, Madrid, Spain; and Centre Hospitalier Universitaire de Hautepierre, Strasbourg</wicri:regionArea><placeName><region type="region">Grand Est</region><region type="old region">Alsace (région administrative)</region><settlement type="city">Strasbourg</settlement></placeName></affiliation></author><author><name sortKey="Guyatt, Gordon" sort="Guyatt, Gordon" uniqKey="Guyatt G" first="Gordon" last="Guyatt">Gordon Guyatt</name><affiliation wicri:level="3"><nlm:affiliation>From University of Alberta and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Cleveland Clinic, Cleveland, Ohio; Queen's University, Kingston, Ontario, Canada; Groote Schuur Hospital and University of Cape Town, Western Cape, South Africa; Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada; Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, and Monash University, Melbourne, Victoria, Australia; The Chinese University of Hong Kong, Hong Kong, China; Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; St. John's Medical College and Research Institute, Bangalore, India; Narayana Hrudayalaya, Bangalore, India; University of North Carolina, Chapel Hill, North Carolina; Schulich School of Medicine & Dentistry at Western University, London, Ontario, Canada; Sant Pau Hospital and Biomedical Research Institute, Autonomous University of Barcelona, Research Center of Cardiovascular Diseases (CIBERCV), Barcelona, Spain; Fundación Cardioinfantil Instituto de Cardiología, Bogotá, and Universidad Autónoma de Bucaramanga, Santander, Colombia; University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy; Medical University of Vienna, Vienna, Austria; Hospital Arzobispo Loayza, Universidad Peruana Cayetano Heredia, Lima, Peru; The University of Texas MD Anderson Cancer Center, Houston, Texas; Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia; CARE Hospitals, Maharanipeta, Visakhapatnam, India; Auckland City Hospital, Auckland, New Zealand; McGill University Health Centre, Montréal, Québec, Canada; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Universitario Fundación Hospital Alcorcon, Madrid, Spain; and Centre Hospitalier Universitaire de Hautepierre, Strasbourg, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>From University of Alberta and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Cleveland Clinic, Cleveland, Ohio; Queen's University, Kingston, Ontario, Canada; Groote Schuur Hospital and University of Cape Town, Western Cape, South Africa; Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada; Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, and Monash University, Melbourne, Victoria, Australia; The Chinese University of Hong Kong, Hong Kong, China; Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; St. John's Medical College and Research Institute, Bangalore, India; Narayana Hrudayalaya, Bangalore, India; University of North Carolina, Chapel Hill, North Carolina; Schulich School of Medicine & Dentistry at Western University, London, Ontario, Canada; Sant Pau Hospital and Biomedical Research Institute, Autonomous University of Barcelona, Research Center of Cardiovascular Diseases (CIBERCV), Barcelona, Spain; Fundación Cardioinfantil Instituto de Cardiología, Bogotá, and Universidad Autónoma de Bucaramanga, Santander, Colombia; University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy; Medical University of Vienna, Vienna, Austria; Hospital Arzobispo Loayza, Universidad Peruana Cayetano Heredia, Lima, Peru; The University of Texas MD Anderson Cancer Center, Houston, Texas; Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia; CARE Hospitals, Maharanipeta, Visakhapatnam, India; Auckland City Hospital, Auckland, New Zealand; McGill University Health Centre, Montréal, Québec, Canada; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Universitario Fundación Hospital Alcorcon, Madrid, Spain; and Centre Hospitalier Universitaire de Hautepierre, Strasbourg</wicri:regionArea><placeName><region type="region">Grand Est</region><region type="old region">Alsace (région administrative)</region><settlement type="city">Strasbourg</settlement></placeName></affiliation></author><author><name sortKey="Leslie, Kate" sort="Leslie, Kate" uniqKey="Leslie K" first="Kate" last="Leslie">Kate Leslie</name><affiliation wicri:level="3"><nlm:affiliation>From University of Alberta and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Cleveland Clinic, Cleveland, Ohio; Queen's University, Kingston, Ontario, Canada; Groote Schuur Hospital and University of Cape Town, Western Cape, South Africa; Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada; Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, and Monash University, Melbourne, Victoria, Australia; The Chinese University of Hong Kong, Hong Kong, China; Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; St. John's Medical College and Research Institute, Bangalore, India; Narayana Hrudayalaya, Bangalore, India; University of North Carolina, Chapel Hill, North Carolina; Schulich School of Medicine & Dentistry at Western University, London, Ontario, Canada; Sant Pau Hospital and Biomedical Research Institute, Autonomous University of Barcelona, Research Center of Cardiovascular Diseases (CIBERCV), Barcelona, Spain; Fundación Cardioinfantil Instituto de Cardiología, Bogotá, and Universidad Autónoma de Bucaramanga, Santander, Colombia; University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy; Medical University of Vienna, Vienna, Austria; Hospital Arzobispo Loayza, Universidad Peruana Cayetano Heredia, Lima, Peru; The University of Texas MD Anderson Cancer Center, Houston, Texas; Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia; CARE Hospitals, Maharanipeta, Visakhapatnam, India; Auckland City Hospital, Auckland, New Zealand; McGill University Health Centre, Montréal, Québec, Canada; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Universitario Fundación Hospital Alcorcon, Madrid, Spain; and Centre Hospitalier Universitaire de Hautepierre, Strasbourg, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>From University of Alberta and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Cleveland Clinic, Cleveland, Ohio; Queen's University, Kingston, Ontario, Canada; Groote Schuur Hospital and University of Cape Town, Western Cape, South Africa; Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada; Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, and Monash University, Melbourne, Victoria, Australia; The Chinese University of Hong Kong, Hong Kong, China; Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; St. John's Medical College and Research Institute, Bangalore, India; Narayana Hrudayalaya, Bangalore, India; University of North Carolina, Chapel Hill, North Carolina; Schulich School of Medicine & Dentistry at Western University, London, Ontario, Canada; Sant Pau Hospital and Biomedical Research Institute, Autonomous University of Barcelona, Research Center of Cardiovascular Diseases (CIBERCV), Barcelona, Spain; Fundación Cardioinfantil Instituto de Cardiología, Bogotá, and Universidad Autónoma de Bucaramanga, Santander, Colombia; University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy; Medical University of Vienna, Vienna, Austria; Hospital Arzobispo Loayza, Universidad Peruana Cayetano Heredia, Lima, Peru; The University of Texas MD Anderson Cancer Center, Houston, Texas; Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia; CARE Hospitals, Maharanipeta, Visakhapatnam, India; Auckland City Hospital, Auckland, New Zealand; McGill University Health Centre, Montréal, Québec, Canada; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Universitario Fundación Hospital Alcorcon, Madrid, Spain; and Centre Hospitalier Universitaire de Hautepierre, Strasbourg</wicri:regionArea><placeName><region type="region">Grand Est</region><region type="old region">Alsace (région administrative)</region><settlement type="city">Strasbourg</settlement></placeName></affiliation></author><author><name sortKey="Chan, Matthew T V" sort="Chan, Matthew T V" uniqKey="Chan M" first="Matthew T V" last="Chan">Matthew T V. Chan</name><affiliation wicri:level="3"><nlm:affiliation>From University of Alberta and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Cleveland Clinic, Cleveland, Ohio; Queen's University, Kingston, Ontario, Canada; Groote Schuur Hospital and University of Cape Town, Western Cape, South Africa; Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada; Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, and Monash University, Melbourne, Victoria, Australia; The Chinese University of Hong Kong, Hong Kong, China; Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; St. John's Medical College and Research Institute, Bangalore, India; Narayana Hrudayalaya, Bangalore, India; University of North Carolina, Chapel Hill, North Carolina; Schulich School of Medicine & Dentistry at Western University, London, Ontario, Canada; Sant Pau Hospital and Biomedical Research Institute, Autonomous University of Barcelona, Research Center of Cardiovascular Diseases (CIBERCV), Barcelona, Spain; Fundación Cardioinfantil Instituto de Cardiología, Bogotá, and Universidad Autónoma de Bucaramanga, Santander, Colombia; University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy; Medical University of Vienna, Vienna, Austria; Hospital Arzobispo Loayza, Universidad Peruana Cayetano Heredia, Lima, Peru; The University of Texas MD Anderson Cancer Center, Houston, Texas; Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia; CARE Hospitals, Maharanipeta, Visakhapatnam, India; Auckland City Hospital, Auckland, New Zealand; McGill University Health Centre, Montréal, Québec, Canada; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Universitario Fundación Hospital Alcorcon, Madrid, Spain; and Centre Hospitalier Universitaire de Hautepierre, Strasbourg, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>From University of Alberta and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Cleveland Clinic, Cleveland, Ohio; Queen's University, Kingston, Ontario, Canada; Groote Schuur Hospital and University of Cape Town, Western Cape, South Africa; Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada; Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, and Monash University, Melbourne, Victoria, Australia; The Chinese University of Hong Kong, Hong Kong, China; Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; St. John's Medical College and Research Institute, Bangalore, India; Narayana Hrudayalaya, Bangalore, India; University of North Carolina, Chapel Hill, North Carolina; Schulich School of Medicine & Dentistry at Western University, London, Ontario, Canada; Sant Pau Hospital and Biomedical Research Institute, Autonomous University of Barcelona, Research Center of Cardiovascular Diseases (CIBERCV), Barcelona, Spain; Fundación Cardioinfantil Instituto de Cardiología, Bogotá, and Universidad Autónoma de Bucaramanga, Santander, Colombia; University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy; Medical University of Vienna, Vienna, Austria; Hospital Arzobispo Loayza, Universidad Peruana Cayetano Heredia, Lima, Peru; The University of Texas MD Anderson Cancer Center, Houston, Texas; Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia; CARE Hospitals, Maharanipeta, Visakhapatnam, India; Auckland City Hospital, Auckland, New Zealand; McGill University Health Centre, Montréal, Québec, Canada; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Universitario Fundación Hospital Alcorcon, Madrid, Spain; and Centre Hospitalier Universitaire de Hautepierre, Strasbourg</wicri:regionArea><placeName><region type="region">Grand Est</region><region type="old region">Alsace (région administrative)</region><settlement type="city">Strasbourg</settlement></placeName></affiliation></author><author><name sortKey="Meyhoff, Christian S" sort="Meyhoff, Christian S" uniqKey="Meyhoff C" first="Christian S" last="Meyhoff">Christian S. Meyhoff</name><affiliation wicri:level="3"><nlm:affiliation>From University of Alberta and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Cleveland Clinic, Cleveland, Ohio; Queen's University, Kingston, Ontario, Canada; Groote Schuur Hospital and University of Cape Town, Western Cape, South Africa; Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada; Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, and Monash University, Melbourne, Victoria, Australia; The Chinese University of Hong Kong, Hong Kong, China; Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; St. John's Medical College and Research Institute, Bangalore, India; Narayana Hrudayalaya, Bangalore, India; University of North Carolina, Chapel Hill, North Carolina; Schulich School of Medicine & Dentistry at Western University, London, Ontario, Canada; Sant Pau Hospital and Biomedical Research Institute, Autonomous University of Barcelona, Research Center of Cardiovascular Diseases (CIBERCV), Barcelona, Spain; Fundación Cardioinfantil Instituto de Cardiología, Bogotá, and Universidad Autónoma de Bucaramanga, Santander, Colombia; University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy; Medical University of Vienna, Vienna, Austria; Hospital Arzobispo Loayza, Universidad Peruana Cayetano Heredia, Lima, Peru; The University of Texas MD Anderson Cancer Center, Houston, Texas; Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia; CARE Hospitals, Maharanipeta, Visakhapatnam, India; Auckland City Hospital, Auckland, New Zealand; McGill University Health Centre, Montréal, Québec, Canada; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Universitario Fundación Hospital Alcorcon, Madrid, Spain; and Centre Hospitalier Universitaire de Hautepierre, Strasbourg, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>From University of Alberta and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Cleveland Clinic, Cleveland, Ohio; Queen's University, Kingston, Ontario, Canada; Groote Schuur Hospital and University of Cape Town, Western Cape, South Africa; Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada; Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, and Monash University, Melbourne, Victoria, Australia; The Chinese University of Hong Kong, Hong Kong, China; Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; St. John's Medical College and Research Institute, Bangalore, India; Narayana Hrudayalaya, Bangalore, India; University of North Carolina, Chapel Hill, North Carolina; Schulich School of Medicine & Dentistry at Western University, London, Ontario, Canada; Sant Pau Hospital and Biomedical Research Institute, Autonomous University of Barcelona, Research Center of Cardiovascular Diseases (CIBERCV), Barcelona, Spain; Fundación Cardioinfantil Instituto de Cardiología, Bogotá, and Universidad Autónoma de Bucaramanga, Santander, Colombia; University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy; Medical University of Vienna, Vienna, Austria; Hospital Arzobispo Loayza, Universidad Peruana Cayetano Heredia, Lima, Peru; The University of Texas MD Anderson Cancer Center, Houston, Texas; Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia; CARE Hospitals, Maharanipeta, Visakhapatnam, India; Auckland City Hospital, Auckland, New Zealand; McGill University Health Centre, Montréal, Québec, Canada; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Universitario Fundación Hospital Alcorcon, Madrid, Spain; and Centre Hospitalier Universitaire de Hautepierre, Strasbourg</wicri:regionArea><placeName><region type="region">Grand Est</region><region type="old region">Alsace (région administrative)</region><settlement type="city">Strasbourg</settlement></placeName></affiliation></author><author><name sortKey="Xavier, Denis" sort="Xavier, Denis" uniqKey="Xavier D" first="Denis" last="Xavier">Denis Xavier</name><affiliation wicri:level="3"><nlm:affiliation>From University of Alberta and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Cleveland Clinic, Cleveland, Ohio; Queen's University, Kingston, Ontario, Canada; Groote Schuur Hospital and University of Cape Town, Western Cape, South Africa; Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada; Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, and Monash University, Melbourne, Victoria, Australia; The Chinese University of Hong Kong, Hong Kong, China; Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; St. John's Medical College and Research Institute, Bangalore, India; Narayana Hrudayalaya, Bangalore, India; University of North Carolina, Chapel Hill, North Carolina; Schulich School of Medicine & Dentistry at Western University, London, Ontario, Canada; Sant Pau Hospital and Biomedical Research Institute, Autonomous University of Barcelona, Research Center of Cardiovascular Diseases (CIBERCV), Barcelona, Spain; Fundación Cardioinfantil Instituto de Cardiología, Bogotá, and Universidad Autónoma de Bucaramanga, Santander, Colombia; University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy; Medical University of Vienna, Vienna, Austria; Hospital Arzobispo Loayza, Universidad Peruana Cayetano Heredia, Lima, Peru; The University of Texas MD Anderson Cancer Center, Houston, Texas; Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia; CARE Hospitals, Maharanipeta, Visakhapatnam, India; Auckland City Hospital, Auckland, New Zealand; McGill University Health Centre, Montréal, Québec, Canada; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Universitario Fundación Hospital Alcorcon, Madrid, Spain; and Centre Hospitalier Universitaire de Hautepierre, Strasbourg, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>From University of Alberta and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Cleveland Clinic, Cleveland, Ohio; Queen's University, Kingston, Ontario, Canada; Groote Schuur Hospital and University of Cape Town, Western Cape, South Africa; Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada; Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, and Monash University, Melbourne, Victoria, Australia; The Chinese University of Hong Kong, Hong Kong, China; Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; St. John's Medical College and Research Institute, Bangalore, India; Narayana Hrudayalaya, Bangalore, India; University of North Carolina, Chapel Hill, North Carolina; Schulich School of Medicine & Dentistry at Western University, London, Ontario, Canada; Sant Pau Hospital and Biomedical Research Institute, Autonomous University of Barcelona, Research Center of Cardiovascular Diseases (CIBERCV), Barcelona, Spain; Fundación Cardioinfantil Instituto de Cardiología, Bogotá, and Universidad Autónoma de Bucaramanga, Santander, Colombia; University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy; Medical University of Vienna, Vienna, Austria; Hospital Arzobispo Loayza, Universidad Peruana Cayetano Heredia, Lima, Peru; The University of Texas MD Anderson Cancer Center, Houston, Texas; Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia; CARE Hospitals, Maharanipeta, Visakhapatnam, India; Auckland City Hospital, Auckland, New Zealand; McGill University Health Centre, Montréal, Québec, Canada; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Universitario Fundación Hospital Alcorcon, Madrid, Spain; and Centre Hospitalier Universitaire de Hautepierre, Strasbourg</wicri:regionArea><placeName><region type="region">Grand Est</region><region type="old region">Alsace (région administrative)</region><settlement type="city">Strasbourg</settlement></placeName></affiliation></author><author><name sortKey="Sigamani, Alben" sort="Sigamani, Alben" uniqKey="Sigamani A" first="Alben" last="Sigamani">Alben Sigamani</name><affiliation wicri:level="3"><nlm:affiliation>From University of Alberta and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Cleveland Clinic, Cleveland, Ohio; Queen's University, Kingston, Ontario, Canada; Groote Schuur Hospital and University of Cape Town, Western Cape, South Africa; Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada; Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, and Monash University, Melbourne, Victoria, Australia; The Chinese University of Hong Kong, Hong Kong, China; Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; St. John's Medical College and Research Institute, Bangalore, India; Narayana Hrudayalaya, Bangalore, India; University of North Carolina, Chapel Hill, North Carolina; Schulich School of Medicine & Dentistry at Western University, London, Ontario, Canada; Sant Pau Hospital and Biomedical Research Institute, Autonomous University of Barcelona, Research Center of Cardiovascular Diseases (CIBERCV), Barcelona, Spain; Fundación Cardioinfantil Instituto de Cardiología, Bogotá, and Universidad Autónoma de Bucaramanga, Santander, Colombia; University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy; Medical University of Vienna, Vienna, Austria; Hospital Arzobispo Loayza, Universidad Peruana Cayetano Heredia, Lima, Peru; The University of Texas MD Anderson Cancer Center, Houston, Texas; Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia; CARE Hospitals, Maharanipeta, Visakhapatnam, India; Auckland City Hospital, Auckland, New Zealand; McGill University Health Centre, Montréal, Québec, Canada; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Universitario Fundación Hospital Alcorcon, Madrid, Spain; and Centre Hospitalier Universitaire de Hautepierre, Strasbourg, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>From University of Alberta and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Cleveland Clinic, Cleveland, Ohio; Queen's University, Kingston, Ontario, Canada; Groote Schuur Hospital and University of Cape Town, Western Cape, South Africa; Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada; Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, and Monash University, Melbourne, Victoria, Australia; The Chinese University of Hong Kong, Hong Kong, China; Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; St. John's Medical College and Research Institute, Bangalore, India; Narayana Hrudayalaya, Bangalore, India; University of North Carolina, Chapel Hill, North Carolina; Schulich School of Medicine & Dentistry at Western University, London, Ontario, Canada; Sant Pau Hospital and Biomedical Research Institute, Autonomous University of Barcelona, Research Center of Cardiovascular Diseases (CIBERCV), Barcelona, Spain; Fundación Cardioinfantil Instituto de Cardiología, Bogotá, and Universidad Autónoma de Bucaramanga, Santander, Colombia; University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy; Medical University of Vienna, Vienna, Austria; Hospital Arzobispo Loayza, Universidad Peruana Cayetano Heredia, Lima, Peru; The University of Texas MD Anderson Cancer Center, Houston, Texas; Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia; CARE Hospitals, Maharanipeta, Visakhapatnam, India; Auckland City Hospital, Auckland, New Zealand; McGill University Health Centre, Montréal, Québec, Canada; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Universitario Fundación Hospital Alcorcon, Madrid, Spain; and Centre Hospitalier Universitaire de Hautepierre, Strasbourg</wicri:regionArea><placeName><region type="region">Grand Est</region><region type="old region">Alsace (région administrative)</region><settlement type="city">Strasbourg</settlement></placeName></affiliation></author><author><name sortKey="Kumar, Priya A" sort="Kumar, Priya A" uniqKey="Kumar P" first="Priya A" last="Kumar">Priya A. Kumar</name><affiliation wicri:level="3"><nlm:affiliation>From University of Alberta and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Cleveland Clinic, Cleveland, Ohio; Queen's University, Kingston, Ontario, Canada; Groote Schuur Hospital and University of Cape Town, Western Cape, South Africa; Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada; Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, and Monash University, Melbourne, Victoria, Australia; The Chinese University of Hong Kong, Hong Kong, China; Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; St. John's Medical College and Research Institute, Bangalore, India; Narayana Hrudayalaya, Bangalore, India; University of North Carolina, Chapel Hill, North Carolina; Schulich School of Medicine & Dentistry at Western University, London, Ontario, Canada; Sant Pau Hospital and Biomedical Research Institute, Autonomous University of Barcelona, Research Center of Cardiovascular Diseases (CIBERCV), Barcelona, Spain; Fundación Cardioinfantil Instituto de Cardiología, Bogotá, and Universidad Autónoma de Bucaramanga, Santander, Colombia; University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy; Medical University of Vienna, Vienna, Austria; Hospital Arzobispo Loayza, Universidad Peruana Cayetano Heredia, Lima, Peru; The University of Texas MD Anderson Cancer Center, Houston, Texas; Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia; CARE Hospitals, Maharanipeta, Visakhapatnam, India; Auckland City Hospital, Auckland, New Zealand; McGill University Health Centre, Montréal, Québec, Canada; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Universitario Fundación Hospital Alcorcon, Madrid, Spain; and Centre Hospitalier Universitaire de Hautepierre, Strasbourg, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>From University of Alberta and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Cleveland Clinic, Cleveland, Ohio; Queen's University, Kingston, Ontario, Canada; Groote Schuur Hospital and University of Cape Town, Western Cape, South Africa; Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada; Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, and Monash University, Melbourne, Victoria, Australia; The Chinese University of Hong Kong, Hong Kong, China; Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; St. John's Medical College and Research Institute, Bangalore, India; Narayana Hrudayalaya, Bangalore, India; University of North Carolina, Chapel Hill, North Carolina; Schulich School of Medicine & Dentistry at Western University, London, Ontario, Canada; Sant Pau Hospital and Biomedical Research Institute, Autonomous University of Barcelona, Research Center of Cardiovascular Diseases (CIBERCV), Barcelona, Spain; Fundación Cardioinfantil Instituto de Cardiología, Bogotá, and Universidad Autónoma de Bucaramanga, Santander, Colombia; University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy; Medical University of Vienna, Vienna, Austria; Hospital Arzobispo Loayza, Universidad Peruana Cayetano Heredia, Lima, Peru; The University of Texas MD Anderson Cancer Center, Houston, Texas; Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia; CARE Hospitals, Maharanipeta, Visakhapatnam, India; Auckland City Hospital, Auckland, New Zealand; McGill University Health Centre, Montréal, Québec, Canada; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Universitario Fundación Hospital Alcorcon, Madrid, Spain; and Centre Hospitalier Universitaire de Hautepierre, Strasbourg</wicri:regionArea><placeName><region type="region">Grand Est</region><region type="old region">Alsace (région administrative)</region><settlement type="city">Strasbourg</settlement></placeName></affiliation></author><author><name sortKey="Mrkobrada, Marko" sort="Mrkobrada, Marko" uniqKey="Mrkobrada M" first="Marko" last="Mrkobrada">Marko Mrkobrada</name><affiliation wicri:level="3"><nlm:affiliation>From University of Alberta and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Cleveland Clinic, Cleveland, Ohio; Queen's University, Kingston, Ontario, Canada; Groote Schuur Hospital and University of Cape Town, Western Cape, South Africa; Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada; Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, and Monash University, Melbourne, Victoria, Australia; The Chinese University of Hong Kong, Hong Kong, China; Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; St. John's Medical College and Research Institute, Bangalore, India; Narayana Hrudayalaya, Bangalore, India; University of North Carolina, Chapel Hill, North Carolina; Schulich School of Medicine & Dentistry at Western University, London, Ontario, Canada; Sant Pau Hospital and Biomedical Research Institute, Autonomous University of Barcelona, Research Center of Cardiovascular Diseases (CIBERCV), Barcelona, Spain; Fundación Cardioinfantil Instituto de Cardiología, Bogotá, and Universidad Autónoma de Bucaramanga, Santander, Colombia; University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy; Medical University of Vienna, Vienna, Austria; Hospital Arzobispo Loayza, Universidad Peruana Cayetano Heredia, Lima, Peru; The University of Texas MD Anderson Cancer Center, Houston, Texas; Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia; CARE Hospitals, Maharanipeta, Visakhapatnam, India; Auckland City Hospital, Auckland, New Zealand; McGill University Health Centre, Montréal, Québec, Canada; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Universitario Fundación Hospital Alcorcon, Madrid, Spain; and Centre Hospitalier Universitaire de Hautepierre, Strasbourg, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>From University of Alberta and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Cleveland Clinic, Cleveland, Ohio; Queen's University, Kingston, Ontario, Canada; Groote Schuur Hospital and University of Cape Town, Western Cape, South Africa; Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada; Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, and Monash University, Melbourne, Victoria, Australia; The Chinese University of Hong Kong, Hong Kong, China; Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; St. John's Medical College and Research Institute, Bangalore, India; Narayana Hrudayalaya, Bangalore, India; University of North Carolina, Chapel Hill, North Carolina; Schulich School of Medicine & Dentistry at Western University, London, Ontario, Canada; Sant Pau Hospital and Biomedical Research Institute, Autonomous University of Barcelona, Research Center of Cardiovascular Diseases (CIBERCV), Barcelona, Spain; Fundación Cardioinfantil Instituto de Cardiología, Bogotá, and Universidad Autónoma de Bucaramanga, Santander, Colombia; University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy; Medical University of Vienna, Vienna, Austria; Hospital Arzobispo Loayza, Universidad Peruana Cayetano Heredia, Lima, Peru; The University of Texas MD Anderson Cancer Center, Houston, Texas; Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia; CARE Hospitals, Maharanipeta, Visakhapatnam, India; Auckland City Hospital, Auckland, New Zealand; McGill University Health Centre, Montréal, Québec, Canada; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Universitario Fundación Hospital Alcorcon, Madrid, Spain; and Centre Hospitalier Universitaire de Hautepierre, Strasbourg</wicri:regionArea><placeName><region type="region">Grand Est</region><region type="old region">Alsace (région administrative)</region><settlement type="city">Strasbourg</settlement></placeName></affiliation></author><author><name sortKey="Cook, Deborah J" sort="Cook, Deborah J" uniqKey="Cook D" first="Deborah J" last="Cook">Deborah J. Cook</name><affiliation wicri:level="3"><nlm:affiliation>From University of Alberta and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Cleveland Clinic, Cleveland, Ohio; Queen's University, Kingston, Ontario, Canada; Groote Schuur Hospital and University of Cape Town, Western Cape, South Africa; Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada; Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, and Monash University, Melbourne, Victoria, Australia; The Chinese University of Hong Kong, Hong Kong, China; Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; St. John's Medical College and Research Institute, Bangalore, India; Narayana Hrudayalaya, Bangalore, India; University of North Carolina, Chapel Hill, North Carolina; Schulich School of Medicine & Dentistry at Western University, London, Ontario, Canada; Sant Pau Hospital and Biomedical Research Institute, Autonomous University of Barcelona, Research Center of Cardiovascular Diseases (CIBERCV), Barcelona, Spain; Fundación Cardioinfantil Instituto de Cardiología, Bogotá, and Universidad Autónoma de Bucaramanga, Santander, Colombia; University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy; Medical University of Vienna, Vienna, Austria; Hospital Arzobispo Loayza, Universidad Peruana Cayetano Heredia, Lima, Peru; The University of Texas MD Anderson Cancer Center, Houston, Texas; Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia; CARE Hospitals, Maharanipeta, Visakhapatnam, India; Auckland City Hospital, Auckland, New Zealand; McGill University Health Centre, Montréal, Québec, Canada; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Universitario Fundación Hospital Alcorcon, Madrid, Spain; and Centre Hospitalier Universitaire de Hautepierre, Strasbourg, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>From University of Alberta and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Cleveland Clinic, Cleveland, Ohio; Queen's University, Kingston, Ontario, Canada; Groote Schuur Hospital and University of Cape Town, Western Cape, South Africa; Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada; Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, and Monash University, Melbourne, Victoria, Australia; The Chinese University of Hong Kong, Hong Kong, China; Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; St. John's Medical College and Research Institute, Bangalore, India; Narayana Hrudayalaya, Bangalore, India; University of North Carolina, Chapel Hill, North Carolina; Schulich School of Medicine & Dentistry at Western University, London, Ontario, Canada; Sant Pau Hospital and Biomedical Research Institute, Autonomous University of Barcelona, Research Center of Cardiovascular Diseases (CIBERCV), Barcelona, Spain; Fundación Cardioinfantil Instituto de Cardiología, Bogotá, and Universidad Autónoma de Bucaramanga, Santander, Colombia; University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy; Medical University of Vienna, Vienna, Austria; Hospital Arzobispo Loayza, Universidad Peruana Cayetano Heredia, Lima, Peru; The University of Texas MD Anderson Cancer Center, Houston, Texas; Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia; CARE Hospitals, Maharanipeta, Visakhapatnam, India; Auckland City Hospital, Auckland, New Zealand; McGill University Health Centre, Montréal, Québec, Canada; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Universitario Fundación Hospital Alcorcon, Madrid, Spain; and Centre Hospitalier Universitaire de Hautepierre, Strasbourg</wicri:regionArea><placeName><region type="region">Grand Est</region><region type="old region">Alsace (région administrative)</region><settlement type="city">Strasbourg</settlement></placeName></affiliation></author><author><name sortKey="Tandon, Vikas" sort="Tandon, Vikas" uniqKey="Tandon V" first="Vikas" last="Tandon">Vikas Tandon</name><affiliation wicri:level="3"><nlm:affiliation>From University of Alberta and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Cleveland Clinic, Cleveland, Ohio; Queen's University, Kingston, Ontario, Canada; Groote Schuur Hospital and University of Cape Town, Western Cape, South Africa; Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada; Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, and Monash University, Melbourne, Victoria, Australia; The Chinese University of Hong Kong, Hong Kong, China; Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; St. John's Medical College and Research Institute, Bangalore, India; Narayana Hrudayalaya, Bangalore, India; University of North Carolina, Chapel Hill, North Carolina; Schulich School of Medicine & Dentistry at Western University, London, Ontario, Canada; Sant Pau Hospital and Biomedical Research Institute, Autonomous University of Barcelona, Research Center of Cardiovascular Diseases (CIBERCV), Barcelona, Spain; Fundación Cardioinfantil Instituto de Cardiología, Bogotá, and Universidad Autónoma de Bucaramanga, Santander, Colombia; University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy; Medical University of Vienna, Vienna, Austria; Hospital Arzobispo Loayza, Universidad Peruana Cayetano Heredia, Lima, Peru; The University of Texas MD Anderson Cancer Center, Houston, Texas; Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia; CARE Hospitals, Maharanipeta, Visakhapatnam, India; Auckland City Hospital, Auckland, New Zealand; McGill University Health Centre, Montréal, Québec, Canada; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Universitario Fundación Hospital Alcorcon, Madrid, Spain; and Centre Hospitalier Universitaire de Hautepierre, Strasbourg, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>From University of Alberta and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Cleveland Clinic, Cleveland, Ohio; Queen's University, Kingston, Ontario, Canada; Groote Schuur Hospital and University of Cape Town, Western Cape, South Africa; Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada; Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, and Monash University, Melbourne, Victoria, Australia; The Chinese University of Hong Kong, Hong Kong, China; Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; St. John's Medical College and Research Institute, Bangalore, India; Narayana Hrudayalaya, Bangalore, India; University of North Carolina, Chapel Hill, North Carolina; Schulich School of Medicine & Dentistry at Western University, London, Ontario, Canada; Sant Pau Hospital and Biomedical Research Institute, Autonomous University of Barcelona, Research Center of Cardiovascular Diseases (CIBERCV), Barcelona, Spain; Fundación Cardioinfantil Instituto de Cardiología, Bogotá, and Universidad Autónoma de Bucaramanga, Santander, Colombia; University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy; Medical University of Vienna, Vienna, Austria; Hospital Arzobispo Loayza, Universidad Peruana Cayetano Heredia, Lima, Peru; The University of Texas MD Anderson Cancer Center, Houston, Texas; Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia; CARE Hospitals, Maharanipeta, Visakhapatnam, India; Auckland City Hospital, Auckland, New Zealand; McGill University Health Centre, Montréal, Québec, Canada; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Universitario Fundación Hospital Alcorcon, Madrid, Spain; and Centre Hospitalier Universitaire de Hautepierre, Strasbourg</wicri:regionArea><placeName><region type="region">Grand Est</region><region type="old region">Alsace (région administrative)</region><settlement type="city">Strasbourg</settlement></placeName></affiliation></author><author><name sortKey="Alvarez Garcia, Jesus" sort="Alvarez Garcia, Jesus" uniqKey="Alvarez Garcia J" first="Jesus" last="Alvarez-Garcia">Jesus Alvarez-Garcia</name><affiliation wicri:level="3"><nlm:affiliation>From University of Alberta and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Cleveland Clinic, Cleveland, Ohio; Queen's University, Kingston, Ontario, Canada; Groote Schuur Hospital and University of Cape Town, Western Cape, South Africa; Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada; Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, and Monash University, Melbourne, Victoria, Australia; The Chinese University of Hong Kong, Hong Kong, China; Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; St. John's Medical College and Research Institute, Bangalore, India; Narayana Hrudayalaya, Bangalore, India; University of North Carolina, Chapel Hill, North Carolina; Schulich School of Medicine & Dentistry at Western University, London, Ontario, Canada; Sant Pau Hospital and Biomedical Research Institute, Autonomous University of Barcelona, Research Center of Cardiovascular Diseases (CIBERCV), Barcelona, Spain; Fundación Cardioinfantil Instituto de Cardiología, Bogotá, and Universidad Autónoma de Bucaramanga, Santander, Colombia; University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy; Medical University of Vienna, Vienna, Austria; Hospital Arzobispo Loayza, Universidad Peruana Cayetano Heredia, Lima, Peru; The University of Texas MD Anderson Cancer Center, Houston, Texas; Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia; CARE Hospitals, Maharanipeta, Visakhapatnam, India; Auckland City Hospital, Auckland, New Zealand; McGill University Health Centre, Montréal, Québec, Canada; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Universitario Fundación Hospital Alcorcon, Madrid, Spain; and Centre Hospitalier Universitaire de Hautepierre, Strasbourg, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>From University of Alberta and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Cleveland Clinic, Cleveland, Ohio; Queen's University, Kingston, Ontario, Canada; Groote Schuur Hospital and University of Cape Town, Western Cape, South Africa; Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada; Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, and Monash University, Melbourne, Victoria, Australia; The Chinese University of Hong Kong, Hong Kong, China; Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; St. John's Medical College and Research Institute, Bangalore, India; Narayana Hrudayalaya, Bangalore, India; University of North Carolina, Chapel Hill, North Carolina; Schulich School of Medicine & Dentistry at Western University, London, Ontario, Canada; Sant Pau Hospital and Biomedical Research Institute, Autonomous University of Barcelona, Research Center of Cardiovascular Diseases (CIBERCV), Barcelona, Spain; Fundación Cardioinfantil Instituto de Cardiología, Bogotá, and Universidad Autónoma de Bucaramanga, Santander, Colombia; University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy; Medical University of Vienna, Vienna, Austria; Hospital Arzobispo Loayza, Universidad Peruana Cayetano Heredia, Lima, Peru; The University of Texas MD Anderson Cancer Center, Houston, Texas; Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia; CARE Hospitals, Maharanipeta, Visakhapatnam, India; Auckland City Hospital, Auckland, New Zealand; McGill University Health Centre, Montréal, Québec, Canada; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Universitario Fundación Hospital Alcorcon, Madrid, Spain; and Centre Hospitalier Universitaire de Hautepierre, Strasbourg</wicri:regionArea><placeName><region type="region">Grand Est</region><region type="old region">Alsace (région administrative)</region><settlement type="city">Strasbourg</settlement></placeName></affiliation></author><author><name sortKey="Villar, Juan Carlos" sort="Villar, Juan Carlos" uniqKey="Villar J" first="Juan Carlos" last="Villar">Juan Carlos Villar</name><affiliation wicri:level="3"><nlm:affiliation>From University of Alberta and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Cleveland Clinic, Cleveland, Ohio; Queen's University, Kingston, Ontario, Canada; Groote Schuur Hospital and University of Cape Town, Western Cape, South Africa; Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada; Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, and Monash University, Melbourne, Victoria, Australia; The Chinese University of Hong Kong, Hong Kong, China; Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; St. John's Medical College and Research Institute, Bangalore, India; Narayana Hrudayalaya, Bangalore, India; University of North Carolina, Chapel Hill, North Carolina; Schulich School of Medicine & Dentistry at Western University, London, Ontario, Canada; Sant Pau Hospital and Biomedical Research Institute, Autonomous University of Barcelona, Research Center of Cardiovascular Diseases (CIBERCV), Barcelona, Spain; Fundación Cardioinfantil Instituto de Cardiología, Bogotá, and Universidad Autónoma de Bucaramanga, Santander, Colombia; University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy; Medical University of Vienna, Vienna, Austria; Hospital Arzobispo Loayza, Universidad Peruana Cayetano Heredia, Lima, Peru; The University of Texas MD Anderson Cancer Center, Houston, Texas; Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia; CARE Hospitals, Maharanipeta, Visakhapatnam, India; Auckland City Hospital, Auckland, New Zealand; McGill University Health Centre, Montréal, Québec, Canada; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Universitario Fundación Hospital Alcorcon, Madrid, Spain; and Centre Hospitalier Universitaire de Hautepierre, Strasbourg, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>From University of Alberta and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Cleveland Clinic, Cleveland, Ohio; Queen's University, Kingston, Ontario, Canada; Groote Schuur Hospital and University of Cape Town, Western Cape, South Africa; Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada; Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, and Monash University, Melbourne, Victoria, Australia; The Chinese University of Hong Kong, Hong Kong, China; Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; St. John's Medical College and Research Institute, Bangalore, India; Narayana Hrudayalaya, Bangalore, India; University of North Carolina, Chapel Hill, North Carolina; Schulich School of Medicine & Dentistry at Western University, London, Ontario, Canada; Sant Pau Hospital and Biomedical Research Institute, Autonomous University of Barcelona, Research Center of Cardiovascular Diseases (CIBERCV), Barcelona, Spain; Fundación Cardioinfantil Instituto de Cardiología, Bogotá, and Universidad Autónoma de Bucaramanga, Santander, Colombia; University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy; Medical University of Vienna, Vienna, Austria; Hospital Arzobispo Loayza, Universidad Peruana Cayetano Heredia, Lima, Peru; The University of Texas MD Anderson Cancer Center, Houston, Texas; Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia; CARE Hospitals, Maharanipeta, Visakhapatnam, India; Auckland City Hospital, Auckland, New Zealand; McGill University Health Centre, Montréal, Québec, Canada; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Universitario Fundación Hospital Alcorcon, Madrid, Spain; and Centre Hospitalier Universitaire de Hautepierre, Strasbourg</wicri:regionArea><placeName><region type="region">Grand Est</region><region type="old region">Alsace (région administrative)</region><settlement type="city">Strasbourg</settlement></placeName></affiliation></author><author><name sortKey="Painter, Thomas W" sort="Painter, Thomas W" uniqKey="Painter T" first="Thomas W" last="Painter">Thomas W. Painter</name><affiliation wicri:level="3"><nlm:affiliation>From University of Alberta and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Cleveland Clinic, Cleveland, Ohio; Queen's University, Kingston, Ontario, Canada; Groote Schuur Hospital and University of Cape Town, Western Cape, South Africa; Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada; Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, and Monash University, Melbourne, Victoria, Australia; The Chinese University of Hong Kong, Hong Kong, China; Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; St. John's Medical College and Research Institute, Bangalore, India; Narayana Hrudayalaya, Bangalore, India; University of North Carolina, Chapel Hill, North Carolina; Schulich School of Medicine & Dentistry at Western University, London, Ontario, Canada; Sant Pau Hospital and Biomedical Research Institute, Autonomous University of Barcelona, Research Center of Cardiovascular Diseases (CIBERCV), Barcelona, Spain; Fundación Cardioinfantil Instituto de Cardiología, Bogotá, and Universidad Autónoma de Bucaramanga, Santander, Colombia; University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy; Medical University of Vienna, Vienna, Austria; Hospital Arzobispo Loayza, Universidad Peruana Cayetano Heredia, Lima, Peru; The University of Texas MD Anderson Cancer Center, Houston, Texas; Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia; CARE Hospitals, Maharanipeta, Visakhapatnam, India; Auckland City Hospital, Auckland, New Zealand; McGill University Health Centre, Montréal, Québec, Canada; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Universitario Fundación Hospital Alcorcon, Madrid, Spain; and Centre Hospitalier Universitaire de Hautepierre, Strasbourg, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>From University of Alberta and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Cleveland Clinic, Cleveland, Ohio; Queen's University, Kingston, Ontario, Canada; Groote Schuur Hospital and University of Cape Town, Western Cape, South Africa; Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada; Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, and Monash University, Melbourne, Victoria, Australia; The Chinese University of Hong Kong, Hong Kong, China; Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; St. John's Medical College and Research Institute, Bangalore, India; Narayana Hrudayalaya, Bangalore, India; University of North Carolina, Chapel Hill, North Carolina; Schulich School of Medicine & Dentistry at Western University, London, Ontario, Canada; Sant Pau Hospital and Biomedical Research Institute, Autonomous University of Barcelona, Research Center of Cardiovascular Diseases (CIBERCV), Barcelona, Spain; Fundación Cardioinfantil Instituto de Cardiología, Bogotá, and Universidad Autónoma de Bucaramanga, Santander, Colombia; University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy; Medical University of Vienna, Vienna, Austria; Hospital Arzobispo Loayza, Universidad Peruana Cayetano Heredia, Lima, Peru; The University of Texas MD Anderson Cancer Center, Houston, Texas; Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia; CARE Hospitals, Maharanipeta, Visakhapatnam, India; Auckland City Hospital, Auckland, New Zealand; McGill University Health Centre, Montréal, Québec, Canada; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Universitario Fundación Hospital Alcorcon, Madrid, Spain; and Centre Hospitalier Universitaire de Hautepierre, Strasbourg</wicri:regionArea><placeName><region type="region">Grand Est</region><region type="old region">Alsace (région administrative)</region><settlement type="city">Strasbourg</settlement></placeName></affiliation></author><author><name sortKey="Landoni, Giovanni" sort="Landoni, Giovanni" uniqKey="Landoni G" first="Giovanni" last="Landoni">Giovanni Landoni</name><affiliation wicri:level="3"><nlm:affiliation>From University of Alberta and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Cleveland Clinic, Cleveland, Ohio; Queen's University, Kingston, Ontario, Canada; Groote Schuur Hospital and University of Cape Town, Western Cape, South Africa; Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada; Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, and Monash University, Melbourne, Victoria, Australia; The Chinese University of Hong Kong, Hong Kong, China; Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; St. John's Medical College and Research Institute, Bangalore, India; Narayana Hrudayalaya, Bangalore, India; University of North Carolina, Chapel Hill, North Carolina; Schulich School of Medicine & Dentistry at Western University, London, Ontario, Canada; Sant Pau Hospital and Biomedical Research Institute, Autonomous University of Barcelona, Research Center of Cardiovascular Diseases (CIBERCV), Barcelona, Spain; Fundación Cardioinfantil Instituto de Cardiología, Bogotá, and Universidad Autónoma de Bucaramanga, Santander, Colombia; University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy; Medical University of Vienna, Vienna, Austria; Hospital Arzobispo Loayza, Universidad Peruana Cayetano Heredia, Lima, Peru; The University of Texas MD Anderson Cancer Center, Houston, Texas; Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia; CARE Hospitals, Maharanipeta, Visakhapatnam, India; Auckland City Hospital, Auckland, New Zealand; McGill University Health Centre, Montréal, Québec, Canada; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Universitario Fundación Hospital Alcorcon, Madrid, Spain; and Centre Hospitalier Universitaire de Hautepierre, Strasbourg, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>From University of Alberta and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Cleveland Clinic, Cleveland, Ohio; Queen's University, Kingston, Ontario, Canada; Groote Schuur Hospital and University of Cape Town, Western Cape, South Africa; Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada; Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, and Monash University, Melbourne, Victoria, Australia; The Chinese University of Hong Kong, Hong Kong, China; Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; St. John's Medical College and Research Institute, Bangalore, India; Narayana Hrudayalaya, Bangalore, India; University of North Carolina, Chapel Hill, North Carolina; Schulich School of Medicine & Dentistry at Western University, London, Ontario, Canada; Sant Pau Hospital and Biomedical Research Institute, Autonomous University of Barcelona, Research Center of Cardiovascular Diseases (CIBERCV), Barcelona, Spain; Fundación Cardioinfantil Instituto de Cardiología, Bogotá, and Universidad Autónoma de Bucaramanga, Santander, Colombia; University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy; Medical University of Vienna, Vienna, Austria; Hospital Arzobispo Loayza, Universidad Peruana Cayetano Heredia, Lima, Peru; The University of Texas MD Anderson Cancer Center, Houston, Texas; Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia; CARE Hospitals, Maharanipeta, Visakhapatnam, India; Auckland City Hospital, Auckland, New Zealand; McGill University Health Centre, Montréal, Québec, Canada; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Universitario Fundación Hospital Alcorcon, Madrid, Spain; and Centre Hospitalier Universitaire de Hautepierre, Strasbourg</wicri:regionArea><placeName><region type="region">Grand Est</region><region type="old region">Alsace (région administrative)</region><settlement type="city">Strasbourg</settlement></placeName></affiliation></author><author><name sortKey="Fleischmann, Edith" sort="Fleischmann, Edith" uniqKey="Fleischmann E" first="Edith" last="Fleischmann">Edith Fleischmann</name><affiliation wicri:level="3"><nlm:affiliation>From University of Alberta and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Cleveland Clinic, Cleveland, Ohio; Queen's University, Kingston, Ontario, Canada; Groote Schuur Hospital and University of Cape Town, Western Cape, South Africa; Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada; Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, and Monash University, Melbourne, Victoria, Australia; The Chinese University of Hong Kong, Hong Kong, China; Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; St. John's Medical College and Research Institute, Bangalore, India; Narayana Hrudayalaya, Bangalore, India; University of North Carolina, Chapel Hill, North Carolina; Schulich School of Medicine & Dentistry at Western University, London, Ontario, Canada; Sant Pau Hospital and Biomedical Research Institute, Autonomous University of Barcelona, Research Center of Cardiovascular Diseases (CIBERCV), Barcelona, Spain; Fundación Cardioinfantil Instituto de Cardiología, Bogotá, and Universidad Autónoma de Bucaramanga, Santander, Colombia; University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy; Medical University of Vienna, Vienna, Austria; Hospital Arzobispo Loayza, Universidad Peruana Cayetano Heredia, Lima, Peru; The University of Texas MD Anderson Cancer Center, Houston, Texas; Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia; CARE Hospitals, Maharanipeta, Visakhapatnam, India; Auckland City Hospital, Auckland, New Zealand; McGill University Health Centre, Montréal, Québec, Canada; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Universitario Fundación Hospital Alcorcon, Madrid, Spain; and Centre Hospitalier Universitaire de Hautepierre, Strasbourg, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>From University of Alberta and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Cleveland Clinic, Cleveland, Ohio; Queen's University, Kingston, Ontario, Canada; Groote Schuur Hospital and University of Cape Town, Western Cape, South Africa; Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada; Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, and Monash University, Melbourne, Victoria, Australia; The Chinese University of Hong Kong, Hong Kong, China; Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; St. John's Medical College and Research Institute, Bangalore, India; Narayana Hrudayalaya, Bangalore, India; University of North Carolina, Chapel Hill, North Carolina; Schulich School of Medicine & Dentistry at Western University, London, Ontario, Canada; Sant Pau Hospital and Biomedical Research Institute, Autonomous University of Barcelona, Research Center of Cardiovascular Diseases (CIBERCV), Barcelona, Spain; Fundación Cardioinfantil Instituto de Cardiología, Bogotá, and Universidad Autónoma de Bucaramanga, Santander, Colombia; University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy; Medical University of Vienna, Vienna, Austria; Hospital Arzobispo Loayza, Universidad Peruana Cayetano Heredia, Lima, Peru; The University of Texas MD Anderson Cancer Center, Houston, Texas; Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia; CARE Hospitals, Maharanipeta, Visakhapatnam, India; Auckland City Hospital, Auckland, New Zealand; McGill University Health Centre, Montréal, Québec, Canada; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Universitario Fundación Hospital Alcorcon, Madrid, Spain; and Centre Hospitalier Universitaire de Hautepierre, Strasbourg</wicri:regionArea><placeName><region type="region">Grand Est</region><region type="old region">Alsace (région administrative)</region><settlement type="city">Strasbourg</settlement></placeName></affiliation></author><author><name sortKey="Lamy, Andre" sort="Lamy, Andre" uniqKey="Lamy A" first="Andre" last="Lamy">Andre Lamy</name><affiliation wicri:level="3"><nlm:affiliation>From University of Alberta and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Cleveland Clinic, Cleveland, Ohio; Queen's University, Kingston, Ontario, Canada; Groote Schuur Hospital and University of Cape Town, Western Cape, South Africa; Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada; Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, and Monash University, Melbourne, Victoria, Australia; The Chinese University of Hong Kong, Hong Kong, China; Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; St. John's Medical College and Research Institute, Bangalore, India; Narayana Hrudayalaya, Bangalore, India; University of North Carolina, Chapel Hill, North Carolina; Schulich School of Medicine & Dentistry at Western University, London, Ontario, Canada; Sant Pau Hospital and Biomedical Research Institute, Autonomous University of Barcelona, Research Center of Cardiovascular Diseases (CIBERCV), Barcelona, Spain; Fundación Cardioinfantil Instituto de Cardiología, Bogotá, and Universidad Autónoma de Bucaramanga, Santander, Colombia; University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy; Medical University of Vienna, Vienna, Austria; Hospital Arzobispo Loayza, Universidad Peruana Cayetano Heredia, Lima, Peru; The University of Texas MD Anderson Cancer Center, Houston, Texas; Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia; CARE Hospitals, Maharanipeta, Visakhapatnam, India; Auckland City Hospital, Auckland, New Zealand; McGill University Health Centre, Montréal, Québec, Canada; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Universitario Fundación Hospital Alcorcon, Madrid, Spain; and Centre Hospitalier Universitaire de Hautepierre, Strasbourg, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>From University of Alberta and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Cleveland Clinic, Cleveland, Ohio; Queen's University, Kingston, Ontario, Canada; Groote Schuur Hospital and University of Cape Town, Western Cape, South Africa; Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada; Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, and Monash University, Melbourne, Victoria, Australia; The Chinese University of Hong Kong, Hong Kong, China; Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; St. John's Medical College and Research Institute, Bangalore, India; Narayana Hrudayalaya, Bangalore, India; University of North Carolina, Chapel Hill, North Carolina; Schulich School of Medicine & Dentistry at Western University, London, Ontario, Canada; Sant Pau Hospital and Biomedical Research Institute, Autonomous University of Barcelona, Research Center of Cardiovascular Diseases (CIBERCV), Barcelona, Spain; Fundación Cardioinfantil Instituto de Cardiología, Bogotá, and Universidad Autónoma de Bucaramanga, Santander, Colombia; University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy; Medical University of Vienna, Vienna, Austria; Hospital Arzobispo Loayza, Universidad Peruana Cayetano Heredia, Lima, Peru; The University of Texas MD Anderson Cancer Center, Houston, Texas; Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia; CARE Hospitals, Maharanipeta, Visakhapatnam, India; Auckland City Hospital, Auckland, New Zealand; McGill University Health Centre, Montréal, Québec, Canada; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Universitario Fundación Hospital Alcorcon, Madrid, Spain; and Centre Hospitalier Universitaire de Hautepierre, Strasbourg</wicri:regionArea><placeName><region type="region">Grand Est</region><region type="old region">Alsace (région administrative)</region><settlement type="city">Strasbourg</settlement></placeName></affiliation></author><author><name sortKey="Whitlock, Richard" sort="Whitlock, Richard" uniqKey="Whitlock R" first="Richard" last="Whitlock">Richard Whitlock</name><affiliation wicri:level="3"><nlm:affiliation>From University of Alberta and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Cleveland Clinic, Cleveland, Ohio; Queen's University, Kingston, Ontario, Canada; Groote Schuur Hospital and University of Cape Town, Western Cape, South Africa; Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada; Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, and Monash University, Melbourne, Victoria, Australia; The Chinese University of Hong Kong, Hong Kong, China; Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; St. John's Medical College and Research Institute, Bangalore, India; Narayana Hrudayalaya, Bangalore, India; University of North Carolina, Chapel Hill, North Carolina; Schulich School of Medicine & Dentistry at Western University, London, Ontario, Canada; Sant Pau Hospital and Biomedical Research Institute, Autonomous University of Barcelona, Research Center of Cardiovascular Diseases (CIBERCV), Barcelona, Spain; Fundación Cardioinfantil Instituto de Cardiología, Bogotá, and Universidad Autónoma de Bucaramanga, Santander, Colombia; University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy; Medical University of Vienna, Vienna, Austria; Hospital Arzobispo Loayza, Universidad Peruana Cayetano Heredia, Lima, Peru; The University of Texas MD Anderson Cancer Center, Houston, Texas; Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia; CARE Hospitals, Maharanipeta, Visakhapatnam, India; Auckland City Hospital, Auckland, New Zealand; McGill University Health Centre, Montréal, Québec, Canada; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Universitario Fundación Hospital Alcorcon, Madrid, Spain; and Centre Hospitalier Universitaire de Hautepierre, Strasbourg, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>From University of Alberta and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Cleveland Clinic, Cleveland, Ohio; Queen's University, Kingston, Ontario, Canada; Groote Schuur Hospital and University of Cape Town, Western Cape, South Africa; Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada; Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, and Monash University, Melbourne, Victoria, Australia; The Chinese University of Hong Kong, Hong Kong, China; Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; St. John's Medical College and Research Institute, Bangalore, India; Narayana Hrudayalaya, Bangalore, India; University of North Carolina, Chapel Hill, North Carolina; Schulich School of Medicine & Dentistry at Western University, London, Ontario, Canada; Sant Pau Hospital and Biomedical Research Institute, Autonomous University of Barcelona, Research Center of Cardiovascular Diseases (CIBERCV), Barcelona, Spain; Fundación Cardioinfantil Instituto de Cardiología, Bogotá, and Universidad Autónoma de Bucaramanga, Santander, Colombia; University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy; Medical University of Vienna, Vienna, Austria; Hospital Arzobispo Loayza, Universidad Peruana Cayetano Heredia, Lima, Peru; The University of Texas MD Anderson Cancer Center, Houston, Texas; Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia; CARE Hospitals, Maharanipeta, Visakhapatnam, India; Auckland City Hospital, Auckland, New Zealand; McGill University Health Centre, Montréal, Québec, Canada; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Universitario Fundación Hospital Alcorcon, Madrid, Spain; and Centre Hospitalier Universitaire de Hautepierre, Strasbourg</wicri:regionArea><placeName><region type="region">Grand Est</region><region type="old region">Alsace (région administrative)</region><settlement type="city">Strasbourg</settlement></placeName></affiliation></author><author><name sortKey="Le Manach, Yannick" sort="Le Manach, Yannick" uniqKey="Le Manach Y" first="Yannick" last="Le Manach">Yannick Le Manach</name><affiliation wicri:level="3"><nlm:affiliation>From University of Alberta and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Cleveland Clinic, Cleveland, Ohio; Queen's University, Kingston, Ontario, Canada; Groote Schuur Hospital and University of Cape Town, Western Cape, South Africa; Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada; Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, and Monash University, Melbourne, Victoria, Australia; The Chinese University of Hong Kong, Hong Kong, China; Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; St. John's Medical College and Research Institute, Bangalore, India; Narayana Hrudayalaya, Bangalore, India; University of North Carolina, Chapel Hill, North Carolina; Schulich School of Medicine & Dentistry at Western University, London, Ontario, Canada; Sant Pau Hospital and Biomedical Research Institute, Autonomous University of Barcelona, Research Center of Cardiovascular Diseases (CIBERCV), Barcelona, Spain; Fundación Cardioinfantil Instituto de Cardiología, Bogotá, and Universidad Autónoma de Bucaramanga, Santander, Colombia; University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy; Medical University of Vienna, Vienna, Austria; Hospital Arzobispo Loayza, Universidad Peruana Cayetano Heredia, Lima, Peru; The University of Texas MD Anderson Cancer Center, Houston, Texas; Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia; CARE Hospitals, Maharanipeta, Visakhapatnam, India; Auckland City Hospital, Auckland, New Zealand; McGill University Health Centre, Montréal, Québec, Canada; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Universitario Fundación Hospital Alcorcon, Madrid, Spain; and Centre Hospitalier Universitaire de Hautepierre, Strasbourg, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>From University of Alberta and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Cleveland Clinic, Cleveland, Ohio; Queen's University, Kingston, Ontario, Canada; Groote Schuur Hospital and University of Cape Town, Western Cape, South Africa; Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada; Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, and Monash University, Melbourne, Victoria, Australia; The Chinese University of Hong Kong, Hong Kong, China; Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; St. John's Medical College and Research Institute, Bangalore, India; Narayana Hrudayalaya, Bangalore, India; University of North Carolina, Chapel Hill, North Carolina; Schulich School of Medicine & Dentistry at Western University, London, Ontario, Canada; Sant Pau Hospital and Biomedical Research Institute, Autonomous University of Barcelona, Research Center of Cardiovascular Diseases (CIBERCV), Barcelona, Spain; Fundación Cardioinfantil Instituto de Cardiología, Bogotá, and Universidad Autónoma de Bucaramanga, Santander, Colombia; University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy; Medical University of Vienna, Vienna, Austria; Hospital Arzobispo Loayza, Universidad Peruana Cayetano Heredia, Lima, Peru; The University of Texas MD Anderson Cancer Center, Houston, Texas; Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia; CARE Hospitals, Maharanipeta, Visakhapatnam, India; Auckland City Hospital, Auckland, New Zealand; McGill University Health Centre, Montréal, Québec, Canada; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Universitario Fundación Hospital Alcorcon, Madrid, Spain; and Centre Hospitalier Universitaire de Hautepierre, Strasbourg</wicri:regionArea><placeName><region type="region">Grand Est</region><region type="old region">Alsace (région administrative)</region><settlement type="city">Strasbourg</settlement></placeName></affiliation></author><author><name sortKey="Aphang Lam, Meylin" sort="Aphang Lam, Meylin" uniqKey="Aphang Lam M" first="Meylin" last="Aphang-Lam">Meylin Aphang-Lam</name><affiliation wicri:level="3"><nlm:affiliation>From University of Alberta and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Cleveland Clinic, Cleveland, Ohio; Queen's University, Kingston, Ontario, Canada; Groote Schuur Hospital and University of Cape Town, Western Cape, South Africa; Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada; Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, and Monash University, Melbourne, Victoria, Australia; The Chinese University of Hong Kong, Hong Kong, China; Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; St. John's Medical College and Research Institute, Bangalore, India; Narayana Hrudayalaya, Bangalore, India; University of North Carolina, Chapel Hill, North Carolina; Schulich School of Medicine & Dentistry at Western University, London, Ontario, Canada; Sant Pau Hospital and Biomedical Research Institute, Autonomous University of Barcelona, Research Center of Cardiovascular Diseases (CIBERCV), Barcelona, Spain; Fundación Cardioinfantil Instituto de Cardiología, Bogotá, and Universidad Autónoma de Bucaramanga, Santander, Colombia; University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy; Medical University of Vienna, Vienna, Austria; Hospital Arzobispo Loayza, Universidad Peruana Cayetano Heredia, Lima, Peru; The University of Texas MD Anderson Cancer Center, Houston, Texas; Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia; CARE Hospitals, Maharanipeta, Visakhapatnam, India; Auckland City Hospital, Auckland, New Zealand; McGill University Health Centre, Montréal, Québec, Canada; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Universitario Fundación Hospital Alcorcon, Madrid, Spain; and Centre Hospitalier Universitaire de Hautepierre, Strasbourg, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>From University of Alberta and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Cleveland Clinic, Cleveland, Ohio; Queen's University, Kingston, Ontario, Canada; Groote Schuur Hospital and University of Cape Town, Western Cape, South Africa; Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada; Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, and Monash University, Melbourne, Victoria, Australia; The Chinese University of Hong Kong, Hong Kong, China; Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; St. John's Medical College and Research Institute, Bangalore, India; Narayana Hrudayalaya, Bangalore, India; University of North Carolina, Chapel Hill, North Carolina; Schulich School of Medicine & Dentistry at Western University, London, Ontario, Canada; Sant Pau Hospital and Biomedical Research Institute, Autonomous University of Barcelona, Research Center of Cardiovascular Diseases (CIBERCV), Barcelona, Spain; Fundación Cardioinfantil Instituto de Cardiología, Bogotá, and Universidad Autónoma de Bucaramanga, Santander, Colombia; University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy; Medical University of Vienna, Vienna, Austria; Hospital Arzobispo Loayza, Universidad Peruana Cayetano Heredia, Lima, Peru; The University of Texas MD Anderson Cancer Center, Houston, Texas; Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia; CARE Hospitals, Maharanipeta, Visakhapatnam, India; Auckland City Hospital, Auckland, New Zealand; McGill University Health Centre, Montréal, Québec, Canada; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Universitario Fundación Hospital Alcorcon, Madrid, Spain; and Centre Hospitalier Universitaire de Hautepierre, Strasbourg</wicri:regionArea><placeName><region type="region">Grand Est</region><region type="old region">Alsace (région administrative)</region><settlement type="city">Strasbourg</settlement></placeName></affiliation></author><author><name sortKey="Cata, Juan P" sort="Cata, Juan P" uniqKey="Cata J" first="Juan P" last="Cata">Juan P. Cata</name><affiliation wicri:level="3"><nlm:affiliation>From University of Alberta and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Cleveland Clinic, Cleveland, Ohio; Queen's University, Kingston, Ontario, Canada; Groote Schuur Hospital and University of Cape Town, Western Cape, South Africa; Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada; Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, and Monash University, Melbourne, Victoria, Australia; The Chinese University of Hong Kong, Hong Kong, China; Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; St. John's Medical College and Research Institute, Bangalore, India; Narayana Hrudayalaya, Bangalore, India; University of North Carolina, Chapel Hill, North Carolina; Schulich School of Medicine & Dentistry at Western University, London, Ontario, Canada; Sant Pau Hospital and Biomedical Research Institute, Autonomous University of Barcelona, Research Center of Cardiovascular Diseases (CIBERCV), Barcelona, Spain; Fundación Cardioinfantil Instituto de Cardiología, Bogotá, and Universidad Autónoma de Bucaramanga, Santander, Colombia; University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy; Medical University of Vienna, Vienna, Austria; Hospital Arzobispo Loayza, Universidad Peruana Cayetano Heredia, Lima, Peru; The University of Texas MD Anderson Cancer Center, Houston, Texas; Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia; CARE Hospitals, Maharanipeta, Visakhapatnam, India; Auckland City Hospital, Auckland, New Zealand; McGill University Health Centre, Montréal, Québec, Canada; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Universitario Fundación Hospital Alcorcon, Madrid, Spain; and Centre Hospitalier Universitaire de Hautepierre, Strasbourg, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>From University of Alberta and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Cleveland Clinic, Cleveland, Ohio; Queen's University, Kingston, Ontario, Canada; Groote Schuur Hospital and University of Cape Town, Western Cape, South Africa; Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada; Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, and Monash University, Melbourne, Victoria, Australia; The Chinese University of Hong Kong, Hong Kong, China; Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; St. John's Medical College and Research Institute, Bangalore, India; Narayana Hrudayalaya, Bangalore, India; University of North Carolina, Chapel Hill, North Carolina; Schulich School of Medicine & Dentistry at Western University, London, Ontario, Canada; Sant Pau Hospital and Biomedical Research Institute, Autonomous University of Barcelona, Research Center of Cardiovascular Diseases (CIBERCV), Barcelona, Spain; Fundación Cardioinfantil Instituto de Cardiología, Bogotá, and Universidad Autónoma de Bucaramanga, Santander, Colombia; University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy; Medical University of Vienna, Vienna, Austria; Hospital Arzobispo Loayza, Universidad Peruana Cayetano Heredia, Lima, Peru; The University of Texas MD Anderson Cancer Center, Houston, Texas; Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia; CARE Hospitals, Maharanipeta, Visakhapatnam, India; Auckland City Hospital, Auckland, New Zealand; McGill University Health Centre, Montréal, Québec, Canada; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Universitario Fundación Hospital Alcorcon, Madrid, Spain; and Centre Hospitalier Universitaire de Hautepierre, Strasbourg</wicri:regionArea><placeName><region type="region">Grand Est</region><region type="old region">Alsace (région administrative)</region><settlement type="city">Strasbourg</settlement></placeName></affiliation></author><author><name sortKey="Gao, Peggy" sort="Gao, Peggy" uniqKey="Gao P" first="Peggy" last="Gao">Peggy Gao</name><affiliation wicri:level="3"><nlm:affiliation>From University of Alberta and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Cleveland Clinic, Cleveland, Ohio; Queen's University, Kingston, Ontario, Canada; Groote Schuur Hospital and University of Cape Town, Western Cape, South Africa; Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada; Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, and Monash University, Melbourne, Victoria, Australia; The Chinese University of Hong Kong, Hong Kong, China; Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; St. John's Medical College and Research Institute, Bangalore, India; Narayana Hrudayalaya, Bangalore, India; University of North Carolina, Chapel Hill, North Carolina; Schulich School of Medicine & Dentistry at Western University, London, Ontario, Canada; Sant Pau Hospital and Biomedical Research Institute, Autonomous University of Barcelona, Research Center of Cardiovascular Diseases (CIBERCV), Barcelona, Spain; Fundación Cardioinfantil Instituto de Cardiología, Bogotá, and Universidad Autónoma de Bucaramanga, Santander, Colombia; University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy; Medical University of Vienna, Vienna, Austria; Hospital Arzobispo Loayza, Universidad Peruana Cayetano Heredia, Lima, Peru; The University of Texas MD Anderson Cancer Center, Houston, Texas; Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia; CARE Hospitals, Maharanipeta, Visakhapatnam, India; Auckland City Hospital, Auckland, New Zealand; McGill University Health Centre, Montréal, Québec, Canada; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Universitario Fundación Hospital Alcorcon, Madrid, Spain; and Centre Hospitalier Universitaire de Hautepierre, Strasbourg, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>From University of Alberta and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Cleveland Clinic, Cleveland, Ohio; Queen's University, Kingston, Ontario, Canada; Groote Schuur Hospital and University of Cape Town, Western Cape, South Africa; Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada; Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, and Monash University, Melbourne, Victoria, Australia; The Chinese University of Hong Kong, Hong Kong, China; Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; St. John's Medical College and Research Institute, Bangalore, India; Narayana Hrudayalaya, Bangalore, India; University of North Carolina, Chapel Hill, North Carolina; Schulich School of Medicine & Dentistry at Western University, London, Ontario, Canada; Sant Pau Hospital and Biomedical Research Institute, Autonomous University of Barcelona, Research Center of Cardiovascular Diseases (CIBERCV), Barcelona, Spain; Fundación Cardioinfantil Instituto de Cardiología, Bogotá, and Universidad Autónoma de Bucaramanga, Santander, Colombia; University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy; Medical University of Vienna, Vienna, Austria; Hospital Arzobispo Loayza, Universidad Peruana Cayetano Heredia, Lima, Peru; The University of Texas MD Anderson Cancer Center, Houston, Texas; Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia; CARE Hospitals, Maharanipeta, Visakhapatnam, India; Auckland City Hospital, Auckland, New Zealand; McGill University Health Centre, Montréal, Québec, Canada; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Universitario Fundación Hospital Alcorcon, Madrid, Spain; and Centre Hospitalier Universitaire de Hautepierre, Strasbourg</wicri:regionArea><placeName><region type="region">Grand Est</region><region type="old region">Alsace (région administrative)</region><settlement type="city">Strasbourg</settlement></placeName></affiliation></author><author><name sortKey="Terblanche, Nicolaas C S" sort="Terblanche, Nicolaas C S" uniqKey="Terblanche N" first="Nicolaas C S" last="Terblanche">Nicolaas C S. Terblanche</name><affiliation wicri:level="3"><nlm:affiliation>From University of Alberta and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Cleveland Clinic, Cleveland, Ohio; Queen's University, Kingston, Ontario, Canada; Groote Schuur Hospital and University of Cape Town, Western Cape, South Africa; Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada; Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, and Monash University, Melbourne, Victoria, Australia; The Chinese University of Hong Kong, Hong Kong, China; Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; St. John's Medical College and Research Institute, Bangalore, India; Narayana Hrudayalaya, Bangalore, India; University of North Carolina, Chapel Hill, North Carolina; Schulich School of Medicine & Dentistry at Western University, London, Ontario, Canada; Sant Pau Hospital and Biomedical Research Institute, Autonomous University of Barcelona, Research Center of Cardiovascular Diseases (CIBERCV), Barcelona, Spain; Fundación Cardioinfantil Instituto de Cardiología, Bogotá, and Universidad Autónoma de Bucaramanga, Santander, Colombia; University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy; Medical University of Vienna, Vienna, Austria; Hospital Arzobispo Loayza, Universidad Peruana Cayetano Heredia, Lima, Peru; The University of Texas MD Anderson Cancer Center, Houston, Texas; Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia; CARE Hospitals, Maharanipeta, Visakhapatnam, India; Auckland City Hospital, Auckland, New Zealand; McGill University Health Centre, Montréal, Québec, Canada; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Universitario Fundación Hospital Alcorcon, Madrid, Spain; and Centre Hospitalier Universitaire de Hautepierre, Strasbourg, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>From University of Alberta and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Cleveland Clinic, Cleveland, Ohio; Queen's University, Kingston, Ontario, Canada; Groote Schuur Hospital and University of Cape Town, Western Cape, South Africa; Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada; Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, and Monash University, Melbourne, Victoria, Australia; The Chinese University of Hong Kong, Hong Kong, China; Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; St. John's Medical College and Research Institute, Bangalore, India; Narayana Hrudayalaya, Bangalore, India; University of North Carolina, Chapel Hill, North Carolina; Schulich School of Medicine & Dentistry at Western University, London, Ontario, Canada; Sant Pau Hospital and Biomedical Research Institute, Autonomous University of Barcelona, Research Center of Cardiovascular Diseases (CIBERCV), Barcelona, Spain; Fundación Cardioinfantil Instituto de Cardiología, Bogotá, and Universidad Autónoma de Bucaramanga, Santander, Colombia; University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy; Medical University of Vienna, Vienna, Austria; Hospital Arzobispo Loayza, Universidad Peruana Cayetano Heredia, Lima, Peru; The University of Texas MD Anderson Cancer Center, Houston, Texas; Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia; CARE Hospitals, Maharanipeta, Visakhapatnam, India; Auckland City Hospital, Auckland, New Zealand; McGill University Health Centre, Montréal, Québec, Canada; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Universitario Fundación Hospital Alcorcon, Madrid, Spain; and Centre Hospitalier Universitaire de Hautepierre, Strasbourg</wicri:regionArea><placeName><region type="region">Grand Est</region><region type="old region">Alsace (région administrative)</region><settlement type="city">Strasbourg</settlement></placeName></affiliation></author><author><name sortKey="Ramana, Pamidimukkala V" sort="Ramana, Pamidimukkala V" uniqKey="Ramana P" first="Pamidimukkala V" last="Ramana">Pamidimukkala V. Ramana</name><affiliation wicri:level="3"><nlm:affiliation>From University of Alberta and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Cleveland Clinic, Cleveland, Ohio; Queen's University, Kingston, Ontario, Canada; Groote Schuur Hospital and University of Cape Town, Western Cape, South Africa; Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada; Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, and Monash University, Melbourne, Victoria, Australia; The Chinese University of Hong Kong, Hong Kong, China; Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; St. John's Medical College and Research Institute, Bangalore, India; Narayana Hrudayalaya, Bangalore, India; University of North Carolina, Chapel Hill, North Carolina; Schulich School of Medicine & Dentistry at Western University, London, Ontario, Canada; Sant Pau Hospital and Biomedical Research Institute, Autonomous University of Barcelona, Research Center of Cardiovascular Diseases (CIBERCV), Barcelona, Spain; Fundación Cardioinfantil Instituto de Cardiología, Bogotá, and Universidad Autónoma de Bucaramanga, Santander, Colombia; University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy; Medical University of Vienna, Vienna, Austria; Hospital Arzobispo Loayza, Universidad Peruana Cayetano Heredia, Lima, Peru; The University of Texas MD Anderson Cancer Center, Houston, Texas; Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia; CARE Hospitals, Maharanipeta, Visakhapatnam, India; Auckland City Hospital, Auckland, New Zealand; McGill University Health Centre, Montréal, Québec, Canada; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Universitario Fundación Hospital Alcorcon, Madrid, Spain; and Centre Hospitalier Universitaire de Hautepierre, Strasbourg, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>From University of Alberta and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Cleveland Clinic, Cleveland, Ohio; Queen's University, Kingston, Ontario, Canada; Groote Schuur Hospital and University of Cape Town, Western Cape, South Africa; Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada; Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, and Monash University, Melbourne, Victoria, Australia; The Chinese University of Hong Kong, Hong Kong, China; Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; St. John's Medical College and Research Institute, Bangalore, India; Narayana Hrudayalaya, Bangalore, India; University of North Carolina, Chapel Hill, North Carolina; Schulich School of Medicine & Dentistry at Western University, London, Ontario, Canada; Sant Pau Hospital and Biomedical Research Institute, Autonomous University of Barcelona, Research Center of Cardiovascular Diseases (CIBERCV), Barcelona, Spain; Fundación Cardioinfantil Instituto de Cardiología, Bogotá, and Universidad Autónoma de Bucaramanga, Santander, Colombia; University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy; Medical University of Vienna, Vienna, Austria; Hospital Arzobispo Loayza, Universidad Peruana Cayetano Heredia, Lima, Peru; The University of Texas MD Anderson Cancer Center, Houston, Texas; Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia; CARE Hospitals, Maharanipeta, Visakhapatnam, India; Auckland City Hospital, Auckland, New Zealand; McGill University Health Centre, Montréal, Québec, Canada; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Universitario Fundación Hospital Alcorcon, Madrid, Spain; and Centre Hospitalier Universitaire de Hautepierre, Strasbourg</wicri:regionArea><placeName><region type="region">Grand Est</region><region type="old region">Alsace (région administrative)</region><settlement type="city">Strasbourg</settlement></placeName></affiliation></author><author><name sortKey="Jamieson, Kim A" sort="Jamieson, Kim A" uniqKey="Jamieson K" first="Kim A" last="Jamieson">Kim A. Jamieson</name><affiliation wicri:level="3"><nlm:affiliation>From University of Alberta and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Cleveland Clinic, Cleveland, Ohio; Queen's University, Kingston, Ontario, Canada; Groote Schuur Hospital and University of Cape Town, Western Cape, South Africa; Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada; Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, and Monash University, Melbourne, Victoria, Australia; The Chinese University of Hong Kong, Hong Kong, China; Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; St. John's Medical College and Research Institute, Bangalore, India; Narayana Hrudayalaya, Bangalore, India; University of North Carolina, Chapel Hill, North Carolina; Schulich School of Medicine & Dentistry at Western University, London, Ontario, Canada; Sant Pau Hospital and Biomedical Research Institute, Autonomous University of Barcelona, Research Center of Cardiovascular Diseases (CIBERCV), Barcelona, Spain; Fundación Cardioinfantil Instituto de Cardiología, Bogotá, and Universidad Autónoma de Bucaramanga, Santander, Colombia; University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy; Medical University of Vienna, Vienna, Austria; Hospital Arzobispo Loayza, Universidad Peruana Cayetano Heredia, Lima, Peru; The University of Texas MD Anderson Cancer Center, Houston, Texas; Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia; CARE Hospitals, Maharanipeta, Visakhapatnam, India; Auckland City Hospital, Auckland, New Zealand; McGill University Health Centre, Montréal, Québec, Canada; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Universitario Fundación Hospital Alcorcon, Madrid, Spain; and Centre Hospitalier Universitaire de Hautepierre, Strasbourg, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>From University of Alberta and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Cleveland Clinic, Cleveland, Ohio; Queen's University, Kingston, Ontario, Canada; Groote Schuur Hospital and University of Cape Town, Western Cape, South Africa; Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada; Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, and Monash University, Melbourne, Victoria, Australia; The Chinese University of Hong Kong, Hong Kong, China; Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; St. John's Medical College and Research Institute, Bangalore, India; Narayana Hrudayalaya, Bangalore, India; University of North Carolina, Chapel Hill, North Carolina; Schulich School of Medicine & Dentistry at Western University, London, Ontario, Canada; Sant Pau Hospital and Biomedical Research Institute, Autonomous University of Barcelona, Research Center of Cardiovascular Diseases (CIBERCV), Barcelona, Spain; Fundación Cardioinfantil Instituto de Cardiología, Bogotá, and Universidad Autónoma de Bucaramanga, Santander, Colombia; University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy; Medical University of Vienna, Vienna, Austria; Hospital Arzobispo Loayza, Universidad Peruana Cayetano Heredia, Lima, Peru; The University of Texas MD Anderson Cancer Center, Houston, Texas; Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia; CARE Hospitals, Maharanipeta, Visakhapatnam, India; Auckland City Hospital, Auckland, New Zealand; McGill University Health Centre, Montréal, Québec, Canada; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Universitario Fundación Hospital Alcorcon, Madrid, Spain; and Centre Hospitalier Universitaire de Hautepierre, Strasbourg</wicri:regionArea><placeName><region type="region">Grand Est</region><region type="old region">Alsace (région administrative)</region><settlement type="city">Strasbourg</settlement></placeName></affiliation></author><author><name sortKey="Bessissow, Amal" sort="Bessissow, Amal" uniqKey="Bessissow A" first="Amal" last="Bessissow">Amal Bessissow</name><affiliation wicri:level="3"><nlm:affiliation>From University of Alberta and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Cleveland Clinic, Cleveland, Ohio; Queen's University, Kingston, Ontario, Canada; Groote Schuur Hospital and University of Cape Town, Western Cape, South Africa; Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada; Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, and Monash University, Melbourne, Victoria, Australia; The Chinese University of Hong Kong, Hong Kong, China; Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; St. John's Medical College and Research Institute, Bangalore, India; Narayana Hrudayalaya, Bangalore, India; University of North Carolina, Chapel Hill, North Carolina; Schulich School of Medicine & Dentistry at Western University, London, Ontario, Canada; Sant Pau Hospital and Biomedical Research Institute, Autonomous University of Barcelona, Research Center of Cardiovascular Diseases (CIBERCV), Barcelona, Spain; Fundación Cardioinfantil Instituto de Cardiología, Bogotá, and Universidad Autónoma de Bucaramanga, Santander, Colombia; University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy; Medical University of Vienna, Vienna, Austria; Hospital Arzobispo Loayza, Universidad Peruana Cayetano Heredia, Lima, Peru; The University of Texas MD Anderson Cancer Center, Houston, Texas; Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia; CARE Hospitals, Maharanipeta, Visakhapatnam, India; Auckland City Hospital, Auckland, New Zealand; McGill University Health Centre, Montréal, Québec, Canada; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Universitario Fundación Hospital Alcorcon, Madrid, Spain; and Centre Hospitalier Universitaire de Hautepierre, Strasbourg, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>From University of Alberta and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Cleveland Clinic, Cleveland, Ohio; Queen's University, Kingston, Ontario, Canada; Groote Schuur Hospital and University of Cape Town, Western Cape, South Africa; Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada; Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, and Monash University, Melbourne, Victoria, Australia; The Chinese University of Hong Kong, Hong Kong, China; Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; St. John's Medical College and Research Institute, Bangalore, India; Narayana Hrudayalaya, Bangalore, India; University of North Carolina, Chapel Hill, North Carolina; Schulich School of Medicine & Dentistry at Western University, London, Ontario, Canada; Sant Pau Hospital and Biomedical Research Institute, Autonomous University of Barcelona, Research Center of Cardiovascular Diseases (CIBERCV), Barcelona, Spain; Fundación Cardioinfantil Instituto de Cardiología, Bogotá, and Universidad Autónoma de Bucaramanga, Santander, Colombia; University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy; Medical University of Vienna, Vienna, Austria; Hospital Arzobispo Loayza, Universidad Peruana Cayetano Heredia, Lima, Peru; The University of Texas MD Anderson Cancer Center, Houston, Texas; Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia; CARE Hospitals, Maharanipeta, Visakhapatnam, India; Auckland City Hospital, Auckland, New Zealand; McGill University Health Centre, Montréal, Québec, Canada; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Universitario Fundación Hospital Alcorcon, Madrid, Spain; and Centre Hospitalier Universitaire de Hautepierre, Strasbourg</wicri:regionArea><placeName><region type="region">Grand Est</region><region type="old region">Alsace (région administrative)</region><settlement type="city">Strasbourg</settlement></placeName></affiliation></author><author><name sortKey="Mendoza, Gabriela R" sort="Mendoza, Gabriela R" uniqKey="Mendoza G" first="Gabriela R" last="Mendoza">Gabriela R. Mendoza</name><affiliation wicri:level="3"><nlm:affiliation>From University of Alberta and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Cleveland Clinic, Cleveland, Ohio; Queen's University, Kingston, Ontario, Canada; Groote Schuur Hospital and University of Cape Town, Western Cape, South Africa; Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada; Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, and Monash University, Melbourne, Victoria, Australia; The Chinese University of Hong Kong, Hong Kong, China; Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; St. John's Medical College and Research Institute, Bangalore, India; Narayana Hrudayalaya, Bangalore, India; University of North Carolina, Chapel Hill, North Carolina; Schulich School of Medicine & Dentistry at Western University, London, Ontario, Canada; Sant Pau Hospital and Biomedical Research Institute, Autonomous University of Barcelona, Research Center of Cardiovascular Diseases (CIBERCV), Barcelona, Spain; Fundación Cardioinfantil Instituto de Cardiología, Bogotá, and Universidad Autónoma de Bucaramanga, Santander, Colombia; University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy; Medical University of Vienna, Vienna, Austria; Hospital Arzobispo Loayza, Universidad Peruana Cayetano Heredia, Lima, Peru; The University of Texas MD Anderson Cancer Center, Houston, Texas; Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia; CARE Hospitals, Maharanipeta, Visakhapatnam, India; Auckland City Hospital, Auckland, New Zealand; McGill University Health Centre, Montréal, Québec, Canada; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Universitario Fundación Hospital Alcorcon, Madrid, Spain; and Centre Hospitalier Universitaire de Hautepierre, Strasbourg, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>From University of Alberta and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Cleveland Clinic, Cleveland, Ohio; Queen's University, Kingston, Ontario, Canada; Groote Schuur Hospital and University of Cape Town, Western Cape, South Africa; Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada; Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, and Monash University, Melbourne, Victoria, Australia; The Chinese University of Hong Kong, Hong Kong, China; Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; St. John's Medical College and Research Institute, Bangalore, India; Narayana Hrudayalaya, Bangalore, India; University of North Carolina, Chapel Hill, North Carolina; Schulich School of Medicine & Dentistry at Western University, London, Ontario, Canada; Sant Pau Hospital and Biomedical Research Institute, Autonomous University of Barcelona, Research Center of Cardiovascular Diseases (CIBERCV), Barcelona, Spain; Fundación Cardioinfantil Instituto de Cardiología, Bogotá, and Universidad Autónoma de Bucaramanga, Santander, Colombia; University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy; Medical University of Vienna, Vienna, Austria; Hospital Arzobispo Loayza, Universidad Peruana Cayetano Heredia, Lima, Peru; The University of Texas MD Anderson Cancer Center, Houston, Texas; Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia; CARE Hospitals, Maharanipeta, Visakhapatnam, India; Auckland City Hospital, Auckland, New Zealand; McGill University Health Centre, Montréal, Québec, Canada; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Universitario Fundación Hospital Alcorcon, Madrid, Spain; and Centre Hospitalier Universitaire de Hautepierre, Strasbourg</wicri:regionArea><placeName><region type="region">Grand Est</region><region type="old region">Alsace (région administrative)</region><settlement type="city">Strasbourg</settlement></placeName></affiliation></author><author><name sortKey="Ramirez, Silvia" sort="Ramirez, Silvia" uniqKey="Ramirez S" first="Silvia" last="Ramirez">Silvia Ramirez</name><affiliation wicri:level="3"><nlm:affiliation>From University of Alberta and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Cleveland Clinic, Cleveland, Ohio; Queen's University, Kingston, Ontario, Canada; Groote Schuur Hospital and University of Cape Town, Western Cape, South Africa; Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada; Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, and Monash University, Melbourne, Victoria, Australia; The Chinese University of Hong Kong, Hong Kong, China; Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; St. John's Medical College and Research Institute, Bangalore, India; Narayana Hrudayalaya, Bangalore, India; University of North Carolina, Chapel Hill, North Carolina; Schulich School of Medicine & Dentistry at Western University, London, Ontario, Canada; Sant Pau Hospital and Biomedical Research Institute, Autonomous University of Barcelona, Research Center of Cardiovascular Diseases (CIBERCV), Barcelona, Spain; Fundación Cardioinfantil Instituto de Cardiología, Bogotá, and Universidad Autónoma de Bucaramanga, Santander, Colombia; University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy; Medical University of Vienna, Vienna, Austria; Hospital Arzobispo Loayza, Universidad Peruana Cayetano Heredia, Lima, Peru; The University of Texas MD Anderson Cancer Center, Houston, Texas; Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia; CARE Hospitals, Maharanipeta, Visakhapatnam, India; Auckland City Hospital, Auckland, New Zealand; McGill University Health Centre, Montréal, Québec, Canada; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Universitario Fundación Hospital Alcorcon, Madrid, Spain; and Centre Hospitalier Universitaire de Hautepierre, Strasbourg, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>From University of Alberta and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Cleveland Clinic, Cleveland, Ohio; Queen's University, Kingston, Ontario, Canada; Groote Schuur Hospital and University of Cape Town, Western Cape, South Africa; Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada; Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, and Monash University, Melbourne, Victoria, Australia; The Chinese University of Hong Kong, Hong Kong, China; Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; St. John's Medical College and Research Institute, Bangalore, India; Narayana Hrudayalaya, Bangalore, India; University of North Carolina, Chapel Hill, North Carolina; Schulich School of Medicine & Dentistry at Western University, London, Ontario, Canada; Sant Pau Hospital and Biomedical Research Institute, Autonomous University of Barcelona, Research Center of Cardiovascular Diseases (CIBERCV), Barcelona, Spain; Fundación Cardioinfantil Instituto de Cardiología, Bogotá, and Universidad Autónoma de Bucaramanga, Santander, Colombia; University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy; Medical University of Vienna, Vienna, Austria; Hospital Arzobispo Loayza, Universidad Peruana Cayetano Heredia, Lima, Peru; The University of Texas MD Anderson Cancer Center, Houston, Texas; Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia; CARE Hospitals, Maharanipeta, Visakhapatnam, India; Auckland City Hospital, Auckland, New Zealand; McGill University Health Centre, Montréal, Québec, Canada; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Universitario Fundación Hospital Alcorcon, Madrid, Spain; and Centre Hospitalier Universitaire de Hautepierre, Strasbourg</wicri:regionArea><placeName><region type="region">Grand Est</region><region type="old region">Alsace (région administrative)</region><settlement type="city">Strasbourg</settlement></placeName></affiliation></author><author><name sortKey="Diemunsch, Pierre A" sort="Diemunsch, Pierre A" uniqKey="Diemunsch P" first="Pierre A" last="Diemunsch">Pierre A. Diemunsch</name><affiliation wicri:level="3"><nlm:affiliation>From University of Alberta and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Cleveland Clinic, Cleveland, Ohio; Queen's University, Kingston, Ontario, Canada; Groote Schuur Hospital and University of Cape Town, Western Cape, South Africa; Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada; Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, and Monash University, Melbourne, Victoria, Australia; The Chinese University of Hong Kong, Hong Kong, China; Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; St. John's Medical College and Research Institute, Bangalore, India; Narayana Hrudayalaya, Bangalore, India; University of North Carolina, Chapel Hill, North Carolina; Schulich School of Medicine & Dentistry at Western University, London, Ontario, Canada; Sant Pau Hospital and Biomedical Research Institute, Autonomous University of Barcelona, Research Center of Cardiovascular Diseases (CIBERCV), Barcelona, Spain; Fundación Cardioinfantil Instituto de Cardiología, Bogotá, and Universidad Autónoma de Bucaramanga, Santander, Colombia; University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy; Medical University of Vienna, Vienna, Austria; Hospital Arzobispo Loayza, Universidad Peruana Cayetano Heredia, Lima, Peru; The University of Texas MD Anderson Cancer Center, Houston, Texas; Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia; CARE Hospitals, Maharanipeta, Visakhapatnam, India; Auckland City Hospital, Auckland, New Zealand; McGill University Health Centre, Montréal, Québec, Canada; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Universitario Fundación Hospital Alcorcon, Madrid, Spain; and Centre Hospitalier Universitaire de Hautepierre, Strasbourg, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>From University of Alberta and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Cleveland Clinic, Cleveland, Ohio; Queen's University, Kingston, Ontario, Canada; Groote Schuur Hospital and University of Cape Town, Western Cape, South Africa; Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada; Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, and Monash University, Melbourne, Victoria, Australia; The Chinese University of Hong Kong, Hong Kong, China; Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; St. John's Medical College and Research Institute, Bangalore, India; Narayana Hrudayalaya, Bangalore, India; University of North Carolina, Chapel Hill, North Carolina; Schulich School of Medicine & Dentistry at Western University, London, Ontario, Canada; Sant Pau Hospital and Biomedical Research Institute, Autonomous University of Barcelona, Research Center of Cardiovascular Diseases (CIBERCV), Barcelona, Spain; Fundación Cardioinfantil Instituto de Cardiología, Bogotá, and Universidad Autónoma de Bucaramanga, Santander, Colombia; University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy; Medical University of Vienna, Vienna, Austria; Hospital Arzobispo Loayza, Universidad Peruana Cayetano Heredia, Lima, Peru; The University of Texas MD Anderson Cancer Center, Houston, Texas; Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia; CARE Hospitals, Maharanipeta, Visakhapatnam, India; Auckland City Hospital, Auckland, New Zealand; McGill University Health Centre, Montréal, Québec, Canada; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Universitario Fundación Hospital Alcorcon, Madrid, Spain; and Centre Hospitalier Universitaire de Hautepierre, Strasbourg</wicri:regionArea><placeName><region type="region">Grand Est</region><region type="old region">Alsace (région administrative)</region><settlement type="city">Strasbourg</settlement></placeName></affiliation></author><author><name sortKey="Yusuf, Salim" sort="Yusuf, Salim" uniqKey="Yusuf S" first="Salim" last="Yusuf">Salim Yusuf</name><affiliation wicri:level="3"><nlm:affiliation>From University of Alberta and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Cleveland Clinic, Cleveland, Ohio; Queen's University, Kingston, Ontario, Canada; Groote Schuur Hospital and University of Cape Town, Western Cape, South Africa; Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada; Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, and Monash University, Melbourne, Victoria, Australia; The Chinese University of Hong Kong, Hong Kong, China; Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; St. John's Medical College and Research Institute, Bangalore, India; Narayana Hrudayalaya, Bangalore, India; University of North Carolina, Chapel Hill, North Carolina; Schulich School of Medicine & Dentistry at Western University, London, Ontario, Canada; Sant Pau Hospital and Biomedical Research Institute, Autonomous University of Barcelona, Research Center of Cardiovascular Diseases (CIBERCV), Barcelona, Spain; Fundación Cardioinfantil Instituto de Cardiología, Bogotá, and Universidad Autónoma de Bucaramanga, Santander, Colombia; University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy; Medical University of Vienna, Vienna, Austria; Hospital Arzobispo Loayza, Universidad Peruana Cayetano Heredia, Lima, Peru; The University of Texas MD Anderson Cancer Center, Houston, Texas; Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia; CARE Hospitals, Maharanipeta, Visakhapatnam, India; Auckland City Hospital, Auckland, New Zealand; McGill University Health Centre, Montréal, Québec, Canada; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Universitario Fundación Hospital Alcorcon, Madrid, Spain; and Centre Hospitalier Universitaire de Hautepierre, Strasbourg, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>From University of Alberta and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Cleveland Clinic, Cleveland, Ohio; Queen's University, Kingston, Ontario, Canada; Groote Schuur Hospital and University of Cape Town, Western Cape, South Africa; Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada; Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, and Monash University, Melbourne, Victoria, Australia; The Chinese University of Hong Kong, Hong Kong, China; Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; St. John's Medical College and Research Institute, Bangalore, India; Narayana Hrudayalaya, Bangalore, India; University of North Carolina, Chapel Hill, North Carolina; Schulich School of Medicine & Dentistry at Western University, London, Ontario, Canada; Sant Pau Hospital and Biomedical Research Institute, Autonomous University of Barcelona, Research Center of Cardiovascular Diseases (CIBERCV), Barcelona, Spain; Fundación Cardioinfantil Instituto de Cardiología, Bogotá, and Universidad Autónoma de Bucaramanga, Santander, Colombia; University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy; Medical University of Vienna, Vienna, Austria; Hospital Arzobispo Loayza, Universidad Peruana Cayetano Heredia, Lima, Peru; The University of Texas MD Anderson Cancer Center, Houston, Texas; Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia; CARE Hospitals, Maharanipeta, Visakhapatnam, India; Auckland City Hospital, Auckland, New Zealand; McGill University Health Centre, Montréal, Québec, Canada; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Universitario Fundación Hospital Alcorcon, Madrid, Spain; and Centre Hospitalier Universitaire de Hautepierre, Strasbourg</wicri:regionArea><placeName><region type="region">Grand Est</region><region type="old region">Alsace (région administrative)</region><settlement type="city">Strasbourg</settlement></placeName></affiliation></author><author><name sortKey="Devereaux, P J" sort="Devereaux, P J" uniqKey="Devereaux P" first="P J" last="Devereaux">P J Devereaux</name><affiliation wicri:level="3"><nlm:affiliation>From University of Alberta and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Cleveland Clinic, Cleveland, Ohio; Queen's University, Kingston, Ontario, Canada; Groote Schuur Hospital and University of Cape Town, Western Cape, South Africa; Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada; Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, and Monash University, Melbourne, Victoria, Australia; The Chinese University of Hong Kong, Hong Kong, China; Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; St. John's Medical College and Research Institute, Bangalore, India; Narayana Hrudayalaya, Bangalore, India; University of North Carolina, Chapel Hill, North Carolina; Schulich School of Medicine & Dentistry at Western University, London, Ontario, Canada; Sant Pau Hospital and Biomedical Research Institute, Autonomous University of Barcelona, Research Center of Cardiovascular Diseases (CIBERCV), Barcelona, Spain; Fundación Cardioinfantil Instituto de Cardiología, Bogotá, and Universidad Autónoma de Bucaramanga, Santander, Colombia; University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy; Medical University of Vienna, Vienna, Austria; Hospital Arzobispo Loayza, Universidad Peruana Cayetano Heredia, Lima, Peru; The University of Texas MD Anderson Cancer Center, Houston, Texas; Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia; CARE Hospitals, Maharanipeta, Visakhapatnam, India; Auckland City Hospital, Auckland, New Zealand; McGill University Health Centre, Montréal, Québec, Canada; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Universitario Fundación Hospital Alcorcon, Madrid, Spain; and Centre Hospitalier Universitaire de Hautepierre, Strasbourg, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>From University of Alberta and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Cleveland Clinic, Cleveland, Ohio; Queen's University, Kingston, Ontario, Canada; Groote Schuur Hospital and University of Cape Town, Western Cape, South Africa; Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada; Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, and Monash University, Melbourne, Victoria, Australia; The Chinese University of Hong Kong, Hong Kong, China; Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; St. John's Medical College and Research Institute, Bangalore, India; Narayana Hrudayalaya, Bangalore, India; University of North Carolina, Chapel Hill, North Carolina; Schulich School of Medicine & Dentistry at Western University, London, Ontario, Canada; Sant Pau Hospital and Biomedical Research Institute, Autonomous University of Barcelona, Research Center of Cardiovascular Diseases (CIBERCV), Barcelona, Spain; Fundación Cardioinfantil Instituto de Cardiología, Bogotá, and Universidad Autónoma de Bucaramanga, Santander, Colombia; University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy; Medical University of Vienna, Vienna, Austria; Hospital Arzobispo Loayza, Universidad Peruana Cayetano Heredia, Lima, Peru; The University of Texas MD Anderson Cancer Center, Houston, Texas; Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia; CARE Hospitals, Maharanipeta, Visakhapatnam, India; Auckland City Hospital, Auckland, New Zealand; McGill University Health Centre, Montréal, Québec, Canada; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Universitario Fundación Hospital Alcorcon, Madrid, Spain; and Centre Hospitalier Universitaire de Hautepierre, Strasbourg</wicri:regionArea><placeName><region type="region">Grand Est</region><region type="old region">Alsace (région administrative)</region><settlement type="city">Strasbourg</settlement></placeName></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2017">2017</date><idno type="RBID">pubmed:29132159</idno><idno type="pmid">29132159</idno><idno type="doi">10.7326/M17-2341</idno><idno type="wicri:Area/PubMed/Corpus">000017</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000017</idno><idno type="wicri:Area/PubMed/Curation">000017</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000017</idno><idno type="wicri:Area/PubMed/Checkpoint">000017</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">000017</idno><idno type="wicri:Area/Ncbi/Merge">005206</idno><idno type="wicri:Area/Ncbi/Curation">005206</idno><idno type="wicri:Area/Ncbi/Checkpoint">005206</idno><idno type="wicri:Area/Main/Merge">001161</idno><idno type="wicri:Area/Main/Curation">001166</idno><idno type="wicri:Area/Main/Exploration">001166</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Aspirin in Patients With Previous Percutaneous Coronary Intervention Undergoing Noncardiac Surgery.</title><author><name sortKey="Graham, Michelle M" sort="Graham, Michelle M" uniqKey="Graham M" first="Michelle M" last="Graham">Michelle M. Graham</name><affiliation wicri:level="3"><nlm:affiliation>From University of Alberta and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Cleveland Clinic, Cleveland, Ohio; Queen's University, Kingston, Ontario, Canada; Groote Schuur Hospital and University of Cape Town, Western Cape, South Africa; Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada; Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, and Monash University, Melbourne, Victoria, Australia; The Chinese University of Hong Kong, Hong Kong, China; Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; St. John's Medical College and Research Institute, Bangalore, India; Narayana Hrudayalaya, Bangalore, India; University of North Carolina, Chapel Hill, North Carolina; Schulich School of Medicine & Dentistry at Western University, London, Ontario, Canada; Sant Pau Hospital and Biomedical Research Institute, Autonomous University of Barcelona, Research Center of Cardiovascular Diseases (CIBERCV), Barcelona, Spain; Fundación Cardioinfantil Instituto de Cardiología, Bogotá, and Universidad Autónoma de Bucaramanga, Santander, Colombia; University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy; Medical University of Vienna, Vienna, Austria; Hospital Arzobispo Loayza, Universidad Peruana Cayetano Heredia, Lima, Peru; The University of Texas MD Anderson Cancer Center, Houston, Texas; Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia; CARE Hospitals, Maharanipeta, Visakhapatnam, India; Auckland City Hospital, Auckland, New Zealand; McGill University Health Centre, Montréal, Québec, Canada; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Universitario Fundación Hospital Alcorcon, Madrid, Spain; and Centre Hospitalier Universitaire de Hautepierre, Strasbourg, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>From University of Alberta and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Cleveland Clinic, Cleveland, Ohio; Queen's University, Kingston, Ontario, Canada; Groote Schuur Hospital and University of Cape Town, Western Cape, South Africa; Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada; Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, and Monash University, Melbourne, Victoria, Australia; The Chinese University of Hong Kong, Hong Kong, China; Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; St. John's Medical College and Research Institute, Bangalore, India; Narayana Hrudayalaya, Bangalore, India; University of North Carolina, Chapel Hill, North Carolina; Schulich School of Medicine & Dentistry at Western University, London, Ontario, Canada; Sant Pau Hospital and Biomedical Research Institute, Autonomous University of Barcelona, Research Center of Cardiovascular Diseases (CIBERCV), Barcelona, Spain; Fundación Cardioinfantil Instituto de Cardiología, Bogotá, and Universidad Autónoma de Bucaramanga, Santander, Colombia; University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy; Medical University of Vienna, Vienna, Austria; Hospital Arzobispo Loayza, Universidad Peruana Cayetano Heredia, Lima, Peru; The University of Texas MD Anderson Cancer Center, Houston, Texas; Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia; CARE Hospitals, Maharanipeta, Visakhapatnam, India; Auckland City Hospital, Auckland, New Zealand; McGill University Health Centre, Montréal, Québec, Canada; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Universitario Fundación Hospital Alcorcon, Madrid, Spain; and Centre Hospitalier Universitaire de Hautepierre, Strasbourg</wicri:regionArea><placeName><region type="region">Grand Est</region><region type="old region">Alsace (région administrative)</region><settlement type="city">Strasbourg</settlement></placeName></affiliation></author><author><name sortKey="Sessler, Daniel I" sort="Sessler, Daniel I" uniqKey="Sessler D" first="Daniel I" last="Sessler">Daniel I. Sessler</name><affiliation wicri:level="3"><nlm:affiliation>From University of Alberta and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Cleveland Clinic, Cleveland, Ohio; Queen's University, Kingston, Ontario, Canada; Groote Schuur Hospital and University of Cape Town, Western Cape, South Africa; Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada; Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, and Monash University, Melbourne, Victoria, Australia; The Chinese University of Hong Kong, Hong Kong, China; Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; St. John's Medical College and Research Institute, Bangalore, India; Narayana Hrudayalaya, Bangalore, India; University of North Carolina, Chapel Hill, North Carolina; Schulich School of Medicine & Dentistry at Western University, London, Ontario, Canada; Sant Pau Hospital and Biomedical Research Institute, Autonomous University of Barcelona, Research Center of Cardiovascular Diseases (CIBERCV), Barcelona, Spain; Fundación Cardioinfantil Instituto de Cardiología, Bogotá, and Universidad Autónoma de Bucaramanga, Santander, Colombia; University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy; Medical University of Vienna, Vienna, Austria; Hospital Arzobispo Loayza, Universidad Peruana Cayetano Heredia, Lima, Peru; The University of Texas MD Anderson Cancer Center, Houston, Texas; Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia; CARE Hospitals, Maharanipeta, Visakhapatnam, India; Auckland City Hospital, Auckland, New Zealand; McGill University Health Centre, Montréal, Québec, Canada; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Universitario Fundación Hospital Alcorcon, Madrid, Spain; and Centre Hospitalier Universitaire de Hautepierre, Strasbourg, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>From University of Alberta and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Cleveland Clinic, Cleveland, Ohio; Queen's University, Kingston, Ontario, Canada; Groote Schuur Hospital and University of Cape Town, Western Cape, South Africa; Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada; Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, and Monash University, Melbourne, Victoria, Australia; The Chinese University of Hong Kong, Hong Kong, China; Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; St. John's Medical College and Research Institute, Bangalore, India; Narayana Hrudayalaya, Bangalore, India; University of North Carolina, Chapel Hill, North Carolina; Schulich School of Medicine & Dentistry at Western University, London, Ontario, Canada; Sant Pau Hospital and Biomedical Research Institute, Autonomous University of Barcelona, Research Center of Cardiovascular Diseases (CIBERCV), Barcelona, Spain; Fundación Cardioinfantil Instituto de Cardiología, Bogotá, and Universidad Autónoma de Bucaramanga, Santander, Colombia; University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy; Medical University of Vienna, Vienna, Austria; Hospital Arzobispo Loayza, Universidad Peruana Cayetano Heredia, Lima, Peru; The University of Texas MD Anderson Cancer Center, Houston, Texas; Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia; CARE Hospitals, Maharanipeta, Visakhapatnam, India; Auckland City Hospital, Auckland, New Zealand; McGill University Health Centre, Montréal, Québec, Canada; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Universitario Fundación Hospital Alcorcon, Madrid, Spain; and Centre Hospitalier Universitaire de Hautepierre, Strasbourg</wicri:regionArea><placeName><region type="region">Grand Est</region><region type="old region">Alsace (région administrative)</region><settlement type="city">Strasbourg</settlement></placeName></affiliation></author><author><name sortKey="Parlow, Joel L" sort="Parlow, Joel L" uniqKey="Parlow J" first="Joel L" last="Parlow">Joel L. Parlow</name><affiliation wicri:level="3"><nlm:affiliation>From University of Alberta and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Cleveland Clinic, Cleveland, Ohio; Queen's University, Kingston, Ontario, Canada; Groote Schuur Hospital and University of Cape Town, Western Cape, South Africa; Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada; Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, and Monash University, Melbourne, Victoria, Australia; The Chinese University of Hong Kong, Hong Kong, China; Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; St. John's Medical College and Research Institute, Bangalore, India; Narayana Hrudayalaya, Bangalore, India; University of North Carolina, Chapel Hill, North Carolina; Schulich School of Medicine & Dentistry at Western University, London, Ontario, Canada; Sant Pau Hospital and Biomedical Research Institute, Autonomous University of Barcelona, Research Center of Cardiovascular Diseases (CIBERCV), Barcelona, Spain; Fundación Cardioinfantil Instituto de Cardiología, Bogotá, and Universidad Autónoma de Bucaramanga, Santander, Colombia; University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy; Medical University of Vienna, Vienna, Austria; Hospital Arzobispo Loayza, Universidad Peruana Cayetano Heredia, Lima, Peru; The University of Texas MD Anderson Cancer Center, Houston, Texas; Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia; CARE Hospitals, Maharanipeta, Visakhapatnam, India; Auckland City Hospital, Auckland, New Zealand; McGill University Health Centre, Montréal, Québec, Canada; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Universitario Fundación Hospital Alcorcon, Madrid, Spain; and Centre Hospitalier Universitaire de Hautepierre, Strasbourg, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>From University of Alberta and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Cleveland Clinic, Cleveland, Ohio; Queen's University, Kingston, Ontario, Canada; Groote Schuur Hospital and University of Cape Town, Western Cape, South Africa; Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada; Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, and Monash University, Melbourne, Victoria, Australia; The Chinese University of Hong Kong, Hong Kong, China; Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; St. John's Medical College and Research Institute, Bangalore, India; Narayana Hrudayalaya, Bangalore, India; University of North Carolina, Chapel Hill, North Carolina; Schulich School of Medicine & Dentistry at Western University, London, Ontario, Canada; Sant Pau Hospital and Biomedical Research Institute, Autonomous University of Barcelona, Research Center of Cardiovascular Diseases (CIBERCV), Barcelona, Spain; Fundación Cardioinfantil Instituto de Cardiología, Bogotá, and Universidad Autónoma de Bucaramanga, Santander, Colombia; University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy; Medical University of Vienna, Vienna, Austria; Hospital Arzobispo Loayza, Universidad Peruana Cayetano Heredia, Lima, Peru; The University of Texas MD Anderson Cancer Center, Houston, Texas; Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia; CARE Hospitals, Maharanipeta, Visakhapatnam, India; Auckland City Hospital, Auckland, New Zealand; McGill University Health Centre, Montréal, Québec, Canada; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Universitario Fundación Hospital Alcorcon, Madrid, Spain; and Centre Hospitalier Universitaire de Hautepierre, Strasbourg</wicri:regionArea><placeName><region type="region">Grand Est</region><region type="old region">Alsace (région administrative)</region><settlement type="city">Strasbourg</settlement></placeName></affiliation></author><author><name sortKey="Biccard, Bruce M" sort="Biccard, Bruce M" uniqKey="Biccard B" first="Bruce M" last="Biccard">Bruce M. Biccard</name><affiliation wicri:level="3"><nlm:affiliation>From University of Alberta and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Cleveland Clinic, Cleveland, Ohio; Queen's University, Kingston, Ontario, Canada; Groote Schuur Hospital and University of Cape Town, Western Cape, South Africa; Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada; Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, and Monash University, Melbourne, Victoria, Australia; The Chinese University of Hong Kong, Hong Kong, China; Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; St. John's Medical College and Research Institute, Bangalore, India; Narayana Hrudayalaya, Bangalore, India; University of North Carolina, Chapel Hill, North Carolina; Schulich School of Medicine & Dentistry at Western University, London, Ontario, Canada; Sant Pau Hospital and Biomedical Research Institute, Autonomous University of Barcelona, Research Center of Cardiovascular Diseases (CIBERCV), Barcelona, Spain; Fundación Cardioinfantil Instituto de Cardiología, Bogotá, and Universidad Autónoma de Bucaramanga, Santander, Colombia; University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy; Medical University of Vienna, Vienna, Austria; Hospital Arzobispo Loayza, Universidad Peruana Cayetano Heredia, Lima, Peru; The University of Texas MD Anderson Cancer Center, Houston, Texas; Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia; CARE Hospitals, Maharanipeta, Visakhapatnam, India; Auckland City Hospital, Auckland, New Zealand; McGill University Health Centre, Montréal, Québec, Canada; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Universitario Fundación Hospital Alcorcon, Madrid, Spain; and Centre Hospitalier Universitaire de Hautepierre, Strasbourg, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>From University of Alberta and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Cleveland Clinic, Cleveland, Ohio; Queen's University, Kingston, Ontario, Canada; Groote Schuur Hospital and University of Cape Town, Western Cape, South Africa; Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada; Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, and Monash University, Melbourne, Victoria, Australia; The Chinese University of Hong Kong, Hong Kong, China; Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; St. John's Medical College and Research Institute, Bangalore, India; Narayana Hrudayalaya, Bangalore, India; University of North Carolina, Chapel Hill, North Carolina; Schulich School of Medicine & Dentistry at Western University, London, Ontario, Canada; Sant Pau Hospital and Biomedical Research Institute, Autonomous University of Barcelona, Research Center of Cardiovascular Diseases (CIBERCV), Barcelona, Spain; Fundación Cardioinfantil Instituto de Cardiología, Bogotá, and Universidad Autónoma de Bucaramanga, Santander, Colombia; University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy; Medical University of Vienna, Vienna, Austria; Hospital Arzobispo Loayza, Universidad Peruana Cayetano Heredia, Lima, Peru; The University of Texas MD Anderson Cancer Center, Houston, Texas; Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia; CARE Hospitals, Maharanipeta, Visakhapatnam, India; Auckland City Hospital, Auckland, New Zealand; McGill University Health Centre, Montréal, Québec, Canada; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Universitario Fundación Hospital Alcorcon, Madrid, Spain; and Centre Hospitalier Universitaire de Hautepierre, Strasbourg</wicri:regionArea><placeName><region type="region">Grand Est</region><region type="old region">Alsace (région administrative)</region><settlement type="city">Strasbourg</settlement></placeName></affiliation></author><author><name sortKey="Guyatt, Gordon" sort="Guyatt, Gordon" uniqKey="Guyatt G" first="Gordon" last="Guyatt">Gordon Guyatt</name><affiliation wicri:level="3"><nlm:affiliation>From University of Alberta and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Cleveland Clinic, Cleveland, Ohio; Queen's University, Kingston, Ontario, Canada; Groote Schuur Hospital and University of Cape Town, Western Cape, South Africa; Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada; Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, and Monash University, Melbourne, Victoria, Australia; The Chinese University of Hong Kong, Hong Kong, China; Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; St. John's Medical College and Research Institute, Bangalore, India; Narayana Hrudayalaya, Bangalore, India; University of North Carolina, Chapel Hill, North Carolina; Schulich School of Medicine & Dentistry at Western University, London, Ontario, Canada; Sant Pau Hospital and Biomedical Research Institute, Autonomous University of Barcelona, Research Center of Cardiovascular Diseases (CIBERCV), Barcelona, Spain; Fundación Cardioinfantil Instituto de Cardiología, Bogotá, and Universidad Autónoma de Bucaramanga, Santander, Colombia; University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy; Medical University of Vienna, Vienna, Austria; Hospital Arzobispo Loayza, Universidad Peruana Cayetano Heredia, Lima, Peru; The University of Texas MD Anderson Cancer Center, Houston, Texas; Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia; CARE Hospitals, Maharanipeta, Visakhapatnam, India; Auckland City Hospital, Auckland, New Zealand; McGill University Health Centre, Montréal, Québec, Canada; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Universitario Fundación Hospital Alcorcon, Madrid, Spain; and Centre Hospitalier Universitaire de Hautepierre, Strasbourg, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>From University of Alberta and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Cleveland Clinic, Cleveland, Ohio; Queen's University, Kingston, Ontario, Canada; Groote Schuur Hospital and University of Cape Town, Western Cape, South Africa; Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada; Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, and Monash University, Melbourne, Victoria, Australia; The Chinese University of Hong Kong, Hong Kong, China; Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; St. John's Medical College and Research Institute, Bangalore, India; Narayana Hrudayalaya, Bangalore, India; University of North Carolina, Chapel Hill, North Carolina; Schulich School of Medicine & Dentistry at Western University, London, Ontario, Canada; Sant Pau Hospital and Biomedical Research Institute, Autonomous University of Barcelona, Research Center of Cardiovascular Diseases (CIBERCV), Barcelona, Spain; Fundación Cardioinfantil Instituto de Cardiología, Bogotá, and Universidad Autónoma de Bucaramanga, Santander, Colombia; University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy; Medical University of Vienna, Vienna, Austria; Hospital Arzobispo Loayza, Universidad Peruana Cayetano Heredia, Lima, Peru; The University of Texas MD Anderson Cancer Center, Houston, Texas; Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia; CARE Hospitals, Maharanipeta, Visakhapatnam, India; Auckland City Hospital, Auckland, New Zealand; McGill University Health Centre, Montréal, Québec, Canada; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Universitario Fundación Hospital Alcorcon, Madrid, Spain; and Centre Hospitalier Universitaire de Hautepierre, Strasbourg</wicri:regionArea><placeName><region type="region">Grand Est</region><region type="old region">Alsace (région administrative)</region><settlement type="city">Strasbourg</settlement></placeName></affiliation></author><author><name sortKey="Leslie, Kate" sort="Leslie, Kate" uniqKey="Leslie K" first="Kate" last="Leslie">Kate Leslie</name><affiliation wicri:level="3"><nlm:affiliation>From University of Alberta and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Cleveland Clinic, Cleveland, Ohio; Queen's University, Kingston, Ontario, Canada; Groote Schuur Hospital and University of Cape Town, Western Cape, South Africa; Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada; Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, and Monash University, Melbourne, Victoria, Australia; The Chinese University of Hong Kong, Hong Kong, China; Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; St. John's Medical College and Research Institute, Bangalore, India; Narayana Hrudayalaya, Bangalore, India; University of North Carolina, Chapel Hill, North Carolina; Schulich School of Medicine & Dentistry at Western University, London, Ontario, Canada; Sant Pau Hospital and Biomedical Research Institute, Autonomous University of Barcelona, Research Center of Cardiovascular Diseases (CIBERCV), Barcelona, Spain; Fundación Cardioinfantil Instituto de Cardiología, Bogotá, and Universidad Autónoma de Bucaramanga, Santander, Colombia; University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy; Medical University of Vienna, Vienna, Austria; Hospital Arzobispo Loayza, Universidad Peruana Cayetano Heredia, Lima, Peru; The University of Texas MD Anderson Cancer Center, Houston, Texas; Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia; CARE Hospitals, Maharanipeta, Visakhapatnam, India; Auckland City Hospital, Auckland, New Zealand; McGill University Health Centre, Montréal, Québec, Canada; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Universitario Fundación Hospital Alcorcon, Madrid, Spain; and Centre Hospitalier Universitaire de Hautepierre, Strasbourg, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>From University of Alberta and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Cleveland Clinic, Cleveland, Ohio; Queen's University, Kingston, Ontario, Canada; Groote Schuur Hospital and University of Cape Town, Western Cape, South Africa; Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada; Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, and Monash University, Melbourne, Victoria, Australia; The Chinese University of Hong Kong, Hong Kong, China; Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; St. John's Medical College and Research Institute, Bangalore, India; Narayana Hrudayalaya, Bangalore, India; University of North Carolina, Chapel Hill, North Carolina; Schulich School of Medicine & Dentistry at Western University, London, Ontario, Canada; Sant Pau Hospital and Biomedical Research Institute, Autonomous University of Barcelona, Research Center of Cardiovascular Diseases (CIBERCV), Barcelona, Spain; Fundación Cardioinfantil Instituto de Cardiología, Bogotá, and Universidad Autónoma de Bucaramanga, Santander, Colombia; University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy; Medical University of Vienna, Vienna, Austria; Hospital Arzobispo Loayza, Universidad Peruana Cayetano Heredia, Lima, Peru; The University of Texas MD Anderson Cancer Center, Houston, Texas; Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia; CARE Hospitals, Maharanipeta, Visakhapatnam, India; Auckland City Hospital, Auckland, New Zealand; McGill University Health Centre, Montréal, Québec, Canada; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Universitario Fundación Hospital Alcorcon, Madrid, Spain; and Centre Hospitalier Universitaire de Hautepierre, Strasbourg</wicri:regionArea><placeName><region type="region">Grand Est</region><region type="old region">Alsace (région administrative)</region><settlement type="city">Strasbourg</settlement></placeName></affiliation></author><author><name sortKey="Chan, Matthew T V" sort="Chan, Matthew T V" uniqKey="Chan M" first="Matthew T V" last="Chan">Matthew T V. Chan</name><affiliation wicri:level="3"><nlm:affiliation>From University of Alberta and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Cleveland Clinic, Cleveland, Ohio; Queen's University, Kingston, Ontario, Canada; Groote Schuur Hospital and University of Cape Town, Western Cape, South Africa; Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada; Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, and Monash University, Melbourne, Victoria, Australia; The Chinese University of Hong Kong, Hong Kong, China; Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; St. John's Medical College and Research Institute, Bangalore, India; Narayana Hrudayalaya, Bangalore, India; University of North Carolina, Chapel Hill, North Carolina; Schulich School of Medicine & Dentistry at Western University, London, Ontario, Canada; Sant Pau Hospital and Biomedical Research Institute, Autonomous University of Barcelona, Research Center of Cardiovascular Diseases (CIBERCV), Barcelona, Spain; Fundación Cardioinfantil Instituto de Cardiología, Bogotá, and Universidad Autónoma de Bucaramanga, Santander, Colombia; University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy; Medical University of Vienna, Vienna, Austria; Hospital Arzobispo Loayza, Universidad Peruana Cayetano Heredia, Lima, Peru; The University of Texas MD Anderson Cancer Center, Houston, Texas; Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia; CARE Hospitals, Maharanipeta, Visakhapatnam, India; Auckland City Hospital, Auckland, New Zealand; McGill University Health Centre, Montréal, Québec, Canada; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Universitario Fundación Hospital Alcorcon, Madrid, Spain; and Centre Hospitalier Universitaire de Hautepierre, Strasbourg, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>From University of Alberta and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Cleveland Clinic, Cleveland, Ohio; Queen's University, Kingston, Ontario, Canada; Groote Schuur Hospital and University of Cape Town, Western Cape, South Africa; Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada; Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, and Monash University, Melbourne, Victoria, Australia; The Chinese University of Hong Kong, Hong Kong, China; Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; St. John's Medical College and Research Institute, Bangalore, India; Narayana Hrudayalaya, Bangalore, India; University of North Carolina, Chapel Hill, North Carolina; Schulich School of Medicine & Dentistry at Western University, London, Ontario, Canada; Sant Pau Hospital and Biomedical Research Institute, Autonomous University of Barcelona, Research Center of Cardiovascular Diseases (CIBERCV), Barcelona, Spain; Fundación Cardioinfantil Instituto de Cardiología, Bogotá, and Universidad Autónoma de Bucaramanga, Santander, Colombia; University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy; Medical University of Vienna, Vienna, Austria; Hospital Arzobispo Loayza, Universidad Peruana Cayetano Heredia, Lima, Peru; The University of Texas MD Anderson Cancer Center, Houston, Texas; Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia; CARE Hospitals, Maharanipeta, Visakhapatnam, India; Auckland City Hospital, Auckland, New Zealand; McGill University Health Centre, Montréal, Québec, Canada; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Universitario Fundación Hospital Alcorcon, Madrid, Spain; and Centre Hospitalier Universitaire de Hautepierre, Strasbourg</wicri:regionArea><placeName><region type="region">Grand Est</region><region type="old region">Alsace (région administrative)</region><settlement type="city">Strasbourg</settlement></placeName></affiliation></author><author><name sortKey="Meyhoff, Christian S" sort="Meyhoff, Christian S" uniqKey="Meyhoff C" first="Christian S" last="Meyhoff">Christian S. Meyhoff</name><affiliation wicri:level="3"><nlm:affiliation>From University of Alberta and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Cleveland Clinic, Cleveland, Ohio; Queen's University, Kingston, Ontario, Canada; Groote Schuur Hospital and University of Cape Town, Western Cape, South Africa; Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada; Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, and Monash University, Melbourne, Victoria, Australia; The Chinese University of Hong Kong, Hong Kong, China; Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; St. John's Medical College and Research Institute, Bangalore, India; Narayana Hrudayalaya, Bangalore, India; University of North Carolina, Chapel Hill, North Carolina; Schulich School of Medicine & Dentistry at Western University, London, Ontario, Canada; Sant Pau Hospital and Biomedical Research Institute, Autonomous University of Barcelona, Research Center of Cardiovascular Diseases (CIBERCV), Barcelona, Spain; Fundación Cardioinfantil Instituto de Cardiología, Bogotá, and Universidad Autónoma de Bucaramanga, Santander, Colombia; University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy; Medical University of Vienna, Vienna, Austria; Hospital Arzobispo Loayza, Universidad Peruana Cayetano Heredia, Lima, Peru; The University of Texas MD Anderson Cancer Center, Houston, Texas; Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia; CARE Hospitals, Maharanipeta, Visakhapatnam, India; Auckland City Hospital, Auckland, New Zealand; McGill University Health Centre, Montréal, Québec, Canada; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Universitario Fundación Hospital Alcorcon, Madrid, Spain; and Centre Hospitalier Universitaire de Hautepierre, Strasbourg, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>From University of Alberta and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Cleveland Clinic, Cleveland, Ohio; Queen's University, Kingston, Ontario, Canada; Groote Schuur Hospital and University of Cape Town, Western Cape, South Africa; Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada; Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, and Monash University, Melbourne, Victoria, Australia; The Chinese University of Hong Kong, Hong Kong, China; Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; St. John's Medical College and Research Institute, Bangalore, India; Narayana Hrudayalaya, Bangalore, India; University of North Carolina, Chapel Hill, North Carolina; Schulich School of Medicine & Dentistry at Western University, London, Ontario, Canada; Sant Pau Hospital and Biomedical Research Institute, Autonomous University of Barcelona, Research Center of Cardiovascular Diseases (CIBERCV), Barcelona, Spain; Fundación Cardioinfantil Instituto de Cardiología, Bogotá, and Universidad Autónoma de Bucaramanga, Santander, Colombia; University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy; Medical University of Vienna, Vienna, Austria; Hospital Arzobispo Loayza, Universidad Peruana Cayetano Heredia, Lima, Peru; The University of Texas MD Anderson Cancer Center, Houston, Texas; Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia; CARE Hospitals, Maharanipeta, Visakhapatnam, India; Auckland City Hospital, Auckland, New Zealand; McGill University Health Centre, Montréal, Québec, Canada; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Universitario Fundación Hospital Alcorcon, Madrid, Spain; and Centre Hospitalier Universitaire de Hautepierre, Strasbourg</wicri:regionArea><placeName><region type="region">Grand Est</region><region type="old region">Alsace (région administrative)</region><settlement type="city">Strasbourg</settlement></placeName></affiliation></author><author><name sortKey="Xavier, Denis" sort="Xavier, Denis" uniqKey="Xavier D" first="Denis" last="Xavier">Denis Xavier</name><affiliation wicri:level="3"><nlm:affiliation>From University of Alberta and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Cleveland Clinic, Cleveland, Ohio; Queen's University, Kingston, Ontario, Canada; Groote Schuur Hospital and University of Cape Town, Western Cape, South Africa; Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada; Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, and Monash University, Melbourne, Victoria, Australia; The Chinese University of Hong Kong, Hong Kong, China; Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; St. John's Medical College and Research Institute, Bangalore, India; Narayana Hrudayalaya, Bangalore, India; University of North Carolina, Chapel Hill, North Carolina; Schulich School of Medicine & Dentistry at Western University, London, Ontario, Canada; Sant Pau Hospital and Biomedical Research Institute, Autonomous University of Barcelona, Research Center of Cardiovascular Diseases (CIBERCV), Barcelona, Spain; Fundación Cardioinfantil Instituto de Cardiología, Bogotá, and Universidad Autónoma de Bucaramanga, Santander, Colombia; University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy; Medical University of Vienna, Vienna, Austria; Hospital Arzobispo Loayza, Universidad Peruana Cayetano Heredia, Lima, Peru; The University of Texas MD Anderson Cancer Center, Houston, Texas; Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia; CARE Hospitals, Maharanipeta, Visakhapatnam, India; Auckland City Hospital, Auckland, New Zealand; McGill University Health Centre, Montréal, Québec, Canada; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Universitario Fundación Hospital Alcorcon, Madrid, Spain; and Centre Hospitalier Universitaire de Hautepierre, Strasbourg, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>From University of Alberta and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Cleveland Clinic, Cleveland, Ohio; Queen's University, Kingston, Ontario, Canada; Groote Schuur Hospital and University of Cape Town, Western Cape, South Africa; Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada; Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, and Monash University, Melbourne, Victoria, Australia; The Chinese University of Hong Kong, Hong Kong, China; Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; St. John's Medical College and Research Institute, Bangalore, India; Narayana Hrudayalaya, Bangalore, India; University of North Carolina, Chapel Hill, North Carolina; Schulich School of Medicine & Dentistry at Western University, London, Ontario, Canada; Sant Pau Hospital and Biomedical Research Institute, Autonomous University of Barcelona, Research Center of Cardiovascular Diseases (CIBERCV), Barcelona, Spain; Fundación Cardioinfantil Instituto de Cardiología, Bogotá, and Universidad Autónoma de Bucaramanga, Santander, Colombia; University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy; Medical University of Vienna, Vienna, Austria; Hospital Arzobispo Loayza, Universidad Peruana Cayetano Heredia, Lima, Peru; The University of Texas MD Anderson Cancer Center, Houston, Texas; Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia; CARE Hospitals, Maharanipeta, Visakhapatnam, India; Auckland City Hospital, Auckland, New Zealand; McGill University Health Centre, Montréal, Québec, Canada; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Universitario Fundación Hospital Alcorcon, Madrid, Spain; and Centre Hospitalier Universitaire de Hautepierre, Strasbourg</wicri:regionArea><placeName><region type="region">Grand Est</region><region type="old region">Alsace (région administrative)</region><settlement type="city">Strasbourg</settlement></placeName></affiliation></author><author><name sortKey="Sigamani, Alben" sort="Sigamani, Alben" uniqKey="Sigamani A" first="Alben" last="Sigamani">Alben Sigamani</name><affiliation wicri:level="3"><nlm:affiliation>From University of Alberta and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Cleveland Clinic, Cleveland, Ohio; Queen's University, Kingston, Ontario, Canada; Groote Schuur Hospital and University of Cape Town, Western Cape, South Africa; Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada; Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, and Monash University, Melbourne, Victoria, Australia; The Chinese University of Hong Kong, Hong Kong, China; Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; St. John's Medical College and Research Institute, Bangalore, India; Narayana Hrudayalaya, Bangalore, India; University of North Carolina, Chapel Hill, North Carolina; Schulich School of Medicine & Dentistry at Western University, London, Ontario, Canada; Sant Pau Hospital and Biomedical Research Institute, Autonomous University of Barcelona, Research Center of Cardiovascular Diseases (CIBERCV), Barcelona, Spain; Fundación Cardioinfantil Instituto de Cardiología, Bogotá, and Universidad Autónoma de Bucaramanga, Santander, Colombia; University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy; Medical University of Vienna, Vienna, Austria; Hospital Arzobispo Loayza, Universidad Peruana Cayetano Heredia, Lima, Peru; The University of Texas MD Anderson Cancer Center, Houston, Texas; Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia; CARE Hospitals, Maharanipeta, Visakhapatnam, India; Auckland City Hospital, Auckland, New Zealand; McGill University Health Centre, Montréal, Québec, Canada; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Universitario Fundación Hospital Alcorcon, Madrid, Spain; and Centre Hospitalier Universitaire de Hautepierre, Strasbourg, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>From University of Alberta and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Cleveland Clinic, Cleveland, Ohio; Queen's University, Kingston, Ontario, Canada; Groote Schuur Hospital and University of Cape Town, Western Cape, South Africa; Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada; Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, and Monash University, Melbourne, Victoria, Australia; The Chinese University of Hong Kong, Hong Kong, China; Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; St. John's Medical College and Research Institute, Bangalore, India; Narayana Hrudayalaya, Bangalore, India; University of North Carolina, Chapel Hill, North Carolina; Schulich School of Medicine & Dentistry at Western University, London, Ontario, Canada; Sant Pau Hospital and Biomedical Research Institute, Autonomous University of Barcelona, Research Center of Cardiovascular Diseases (CIBERCV), Barcelona, Spain; Fundación Cardioinfantil Instituto de Cardiología, Bogotá, and Universidad Autónoma de Bucaramanga, Santander, Colombia; University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy; Medical University of Vienna, Vienna, Austria; Hospital Arzobispo Loayza, Universidad Peruana Cayetano Heredia, Lima, Peru; The University of Texas MD Anderson Cancer Center, Houston, Texas; Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia; CARE Hospitals, Maharanipeta, Visakhapatnam, India; Auckland City Hospital, Auckland, New Zealand; McGill University Health Centre, Montréal, Québec, Canada; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Universitario Fundación Hospital Alcorcon, Madrid, Spain; and Centre Hospitalier Universitaire de Hautepierre, Strasbourg</wicri:regionArea><placeName><region type="region">Grand Est</region><region type="old region">Alsace (région administrative)</region><settlement type="city">Strasbourg</settlement></placeName></affiliation></author><author><name sortKey="Kumar, Priya A" sort="Kumar, Priya A" uniqKey="Kumar P" first="Priya A" last="Kumar">Priya A. Kumar</name><affiliation wicri:level="3"><nlm:affiliation>From University of Alberta and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Cleveland Clinic, Cleveland, Ohio; Queen's University, Kingston, Ontario, Canada; Groote Schuur Hospital and University of Cape Town, Western Cape, South Africa; Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada; Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, and Monash University, Melbourne, Victoria, Australia; The Chinese University of Hong Kong, Hong Kong, China; Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; St. John's Medical College and Research Institute, Bangalore, India; Narayana Hrudayalaya, Bangalore, India; University of North Carolina, Chapel Hill, North Carolina; Schulich School of Medicine & Dentistry at Western University, London, Ontario, Canada; Sant Pau Hospital and Biomedical Research Institute, Autonomous University of Barcelona, Research Center of Cardiovascular Diseases (CIBERCV), Barcelona, Spain; Fundación Cardioinfantil Instituto de Cardiología, Bogotá, and Universidad Autónoma de Bucaramanga, Santander, Colombia; University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy; Medical University of Vienna, Vienna, Austria; Hospital Arzobispo Loayza, Universidad Peruana Cayetano Heredia, Lima, Peru; The University of Texas MD Anderson Cancer Center, Houston, Texas; Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia; CARE Hospitals, Maharanipeta, Visakhapatnam, India; Auckland City Hospital, Auckland, New Zealand; McGill University Health Centre, Montréal, Québec, Canada; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Universitario Fundación Hospital Alcorcon, Madrid, Spain; and Centre Hospitalier Universitaire de Hautepierre, Strasbourg, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>From University of Alberta and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Cleveland Clinic, Cleveland, Ohio; Queen's University, Kingston, Ontario, Canada; Groote Schuur Hospital and University of Cape Town, Western Cape, South Africa; Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada; Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, and Monash University, Melbourne, Victoria, Australia; The Chinese University of Hong Kong, Hong Kong, China; Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; St. John's Medical College and Research Institute, Bangalore, India; Narayana Hrudayalaya, Bangalore, India; University of North Carolina, Chapel Hill, North Carolina; Schulich School of Medicine & Dentistry at Western University, London, Ontario, Canada; Sant Pau Hospital and Biomedical Research Institute, Autonomous University of Barcelona, Research Center of Cardiovascular Diseases (CIBERCV), Barcelona, Spain; Fundación Cardioinfantil Instituto de Cardiología, Bogotá, and Universidad Autónoma de Bucaramanga, Santander, Colombia; University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy; Medical University of Vienna, Vienna, Austria; Hospital Arzobispo Loayza, Universidad Peruana Cayetano Heredia, Lima, Peru; The University of Texas MD Anderson Cancer Center, Houston, Texas; Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia; CARE Hospitals, Maharanipeta, Visakhapatnam, India; Auckland City Hospital, Auckland, New Zealand; McGill University Health Centre, Montréal, Québec, Canada; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Universitario Fundación Hospital Alcorcon, Madrid, Spain; and Centre Hospitalier Universitaire de Hautepierre, Strasbourg</wicri:regionArea><placeName><region type="region">Grand Est</region><region type="old region">Alsace (région administrative)</region><settlement type="city">Strasbourg</settlement></placeName></affiliation></author><author><name sortKey="Mrkobrada, Marko" sort="Mrkobrada, Marko" uniqKey="Mrkobrada M" first="Marko" last="Mrkobrada">Marko Mrkobrada</name><affiliation wicri:level="3"><nlm:affiliation>From University of Alberta and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Cleveland Clinic, Cleveland, Ohio; Queen's University, Kingston, Ontario, Canada; Groote Schuur Hospital and University of Cape Town, Western Cape, South Africa; Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada; Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, and Monash University, Melbourne, Victoria, Australia; The Chinese University of Hong Kong, Hong Kong, China; Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; St. John's Medical College and Research Institute, Bangalore, India; Narayana Hrudayalaya, Bangalore, India; University of North Carolina, Chapel Hill, North Carolina; Schulich School of Medicine & Dentistry at Western University, London, Ontario, Canada; Sant Pau Hospital and Biomedical Research Institute, Autonomous University of Barcelona, Research Center of Cardiovascular Diseases (CIBERCV), Barcelona, Spain; Fundación Cardioinfantil Instituto de Cardiología, Bogotá, and Universidad Autónoma de Bucaramanga, Santander, Colombia; University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy; Medical University of Vienna, Vienna, Austria; Hospital Arzobispo Loayza, Universidad Peruana Cayetano Heredia, Lima, Peru; The University of Texas MD Anderson Cancer Center, Houston, Texas; Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia; CARE Hospitals, Maharanipeta, Visakhapatnam, India; Auckland City Hospital, Auckland, New Zealand; McGill University Health Centre, Montréal, Québec, Canada; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Universitario Fundación Hospital Alcorcon, Madrid, Spain; and Centre Hospitalier Universitaire de Hautepierre, Strasbourg, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>From University of Alberta and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Cleveland Clinic, Cleveland, Ohio; Queen's University, Kingston, Ontario, Canada; Groote Schuur Hospital and University of Cape Town, Western Cape, South Africa; Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada; Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, and Monash University, Melbourne, Victoria, Australia; The Chinese University of Hong Kong, Hong Kong, China; Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; St. John's Medical College and Research Institute, Bangalore, India; Narayana Hrudayalaya, Bangalore, India; University of North Carolina, Chapel Hill, North Carolina; Schulich School of Medicine & Dentistry at Western University, London, Ontario, Canada; Sant Pau Hospital and Biomedical Research Institute, Autonomous University of Barcelona, Research Center of Cardiovascular Diseases (CIBERCV), Barcelona, Spain; Fundación Cardioinfantil Instituto de Cardiología, Bogotá, and Universidad Autónoma de Bucaramanga, Santander, Colombia; University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy; Medical University of Vienna, Vienna, Austria; Hospital Arzobispo Loayza, Universidad Peruana Cayetano Heredia, Lima, Peru; The University of Texas MD Anderson Cancer Center, Houston, Texas; Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia; CARE Hospitals, Maharanipeta, Visakhapatnam, India; Auckland City Hospital, Auckland, New Zealand; McGill University Health Centre, Montréal, Québec, Canada; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Universitario Fundación Hospital Alcorcon, Madrid, Spain; and Centre Hospitalier Universitaire de Hautepierre, Strasbourg</wicri:regionArea><placeName><region type="region">Grand Est</region><region type="old region">Alsace (région administrative)</region><settlement type="city">Strasbourg</settlement></placeName></affiliation></author><author><name sortKey="Cook, Deborah J" sort="Cook, Deborah J" uniqKey="Cook D" first="Deborah J" last="Cook">Deborah J. Cook</name><affiliation wicri:level="3"><nlm:affiliation>From University of Alberta and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Cleveland Clinic, Cleveland, Ohio; Queen's University, Kingston, Ontario, Canada; Groote Schuur Hospital and University of Cape Town, Western Cape, South Africa; Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada; Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, and Monash University, Melbourne, Victoria, Australia; The Chinese University of Hong Kong, Hong Kong, China; Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; St. John's Medical College and Research Institute, Bangalore, India; Narayana Hrudayalaya, Bangalore, India; University of North Carolina, Chapel Hill, North Carolina; Schulich School of Medicine & Dentistry at Western University, London, Ontario, Canada; Sant Pau Hospital and Biomedical Research Institute, Autonomous University of Barcelona, Research Center of Cardiovascular Diseases (CIBERCV), Barcelona, Spain; Fundación Cardioinfantil Instituto de Cardiología, Bogotá, and Universidad Autónoma de Bucaramanga, Santander, Colombia; University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy; Medical University of Vienna, Vienna, Austria; Hospital Arzobispo Loayza, Universidad Peruana Cayetano Heredia, Lima, Peru; The University of Texas MD Anderson Cancer Center, Houston, Texas; Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia; CARE Hospitals, Maharanipeta, Visakhapatnam, India; Auckland City Hospital, Auckland, New Zealand; McGill University Health Centre, Montréal, Québec, Canada; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Universitario Fundación Hospital Alcorcon, Madrid, Spain; and Centre Hospitalier Universitaire de Hautepierre, Strasbourg, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>From University of Alberta and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Cleveland Clinic, Cleveland, Ohio; Queen's University, Kingston, Ontario, Canada; Groote Schuur Hospital and University of Cape Town, Western Cape, South Africa; Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada; Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, and Monash University, Melbourne, Victoria, Australia; The Chinese University of Hong Kong, Hong Kong, China; Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; St. John's Medical College and Research Institute, Bangalore, India; Narayana Hrudayalaya, Bangalore, India; University of North Carolina, Chapel Hill, North Carolina; Schulich School of Medicine & Dentistry at Western University, London, Ontario, Canada; Sant Pau Hospital and Biomedical Research Institute, Autonomous University of Barcelona, Research Center of Cardiovascular Diseases (CIBERCV), Barcelona, Spain; Fundación Cardioinfantil Instituto de Cardiología, Bogotá, and Universidad Autónoma de Bucaramanga, Santander, Colombia; University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy; Medical University of Vienna, Vienna, Austria; Hospital Arzobispo Loayza, Universidad Peruana Cayetano Heredia, Lima, Peru; The University of Texas MD Anderson Cancer Center, Houston, Texas; Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia; CARE Hospitals, Maharanipeta, Visakhapatnam, India; Auckland City Hospital, Auckland, New Zealand; McGill University Health Centre, Montréal, Québec, Canada; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Universitario Fundación Hospital Alcorcon, Madrid, Spain; and Centre Hospitalier Universitaire de Hautepierre, Strasbourg</wicri:regionArea><placeName><region type="region">Grand Est</region><region type="old region">Alsace (région administrative)</region><settlement type="city">Strasbourg</settlement></placeName></affiliation></author><author><name sortKey="Tandon, Vikas" sort="Tandon, Vikas" uniqKey="Tandon V" first="Vikas" last="Tandon">Vikas Tandon</name><affiliation wicri:level="3"><nlm:affiliation>From University of Alberta and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Cleveland Clinic, Cleveland, Ohio; Queen's University, Kingston, Ontario, Canada; Groote Schuur Hospital and University of Cape Town, Western Cape, South Africa; Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada; Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, and Monash University, Melbourne, Victoria, Australia; The Chinese University of Hong Kong, Hong Kong, China; Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; St. John's Medical College and Research Institute, Bangalore, India; Narayana Hrudayalaya, Bangalore, India; University of North Carolina, Chapel Hill, North Carolina; Schulich School of Medicine & Dentistry at Western University, London, Ontario, Canada; Sant Pau Hospital and Biomedical Research Institute, Autonomous University of Barcelona, Research Center of Cardiovascular Diseases (CIBERCV), Barcelona, Spain; Fundación Cardioinfantil Instituto de Cardiología, Bogotá, and Universidad Autónoma de Bucaramanga, Santander, Colombia; University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy; Medical University of Vienna, Vienna, Austria; Hospital Arzobispo Loayza, Universidad Peruana Cayetano Heredia, Lima, Peru; The University of Texas MD Anderson Cancer Center, Houston, Texas; Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia; CARE Hospitals, Maharanipeta, Visakhapatnam, India; Auckland City Hospital, Auckland, New Zealand; McGill University Health Centre, Montréal, Québec, Canada; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Universitario Fundación Hospital Alcorcon, Madrid, Spain; and Centre Hospitalier Universitaire de Hautepierre, Strasbourg, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>From University of Alberta and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Cleveland Clinic, Cleveland, Ohio; Queen's University, Kingston, Ontario, Canada; Groote Schuur Hospital and University of Cape Town, Western Cape, South Africa; Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada; Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, and Monash University, Melbourne, Victoria, Australia; The Chinese University of Hong Kong, Hong Kong, China; Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; St. John's Medical College and Research Institute, Bangalore, India; Narayana Hrudayalaya, Bangalore, India; University of North Carolina, Chapel Hill, North Carolina; Schulich School of Medicine & Dentistry at Western University, London, Ontario, Canada; Sant Pau Hospital and Biomedical Research Institute, Autonomous University of Barcelona, Research Center of Cardiovascular Diseases (CIBERCV), Barcelona, Spain; Fundación Cardioinfantil Instituto de Cardiología, Bogotá, and Universidad Autónoma de Bucaramanga, Santander, Colombia; University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy; Medical University of Vienna, Vienna, Austria; Hospital Arzobispo Loayza, Universidad Peruana Cayetano Heredia, Lima, Peru; The University of Texas MD Anderson Cancer Center, Houston, Texas; Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia; CARE Hospitals, Maharanipeta, Visakhapatnam, India; Auckland City Hospital, Auckland, New Zealand; McGill University Health Centre, Montréal, Québec, Canada; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Universitario Fundación Hospital Alcorcon, Madrid, Spain; and Centre Hospitalier Universitaire de Hautepierre, Strasbourg</wicri:regionArea><placeName><region type="region">Grand Est</region><region type="old region">Alsace (région administrative)</region><settlement type="city">Strasbourg</settlement></placeName></affiliation></author><author><name sortKey="Alvarez Garcia, Jesus" sort="Alvarez Garcia, Jesus" uniqKey="Alvarez Garcia J" first="Jesus" last="Alvarez-Garcia">Jesus Alvarez-Garcia</name><affiliation wicri:level="3"><nlm:affiliation>From University of Alberta and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Cleveland Clinic, Cleveland, Ohio; Queen's University, Kingston, Ontario, Canada; Groote Schuur Hospital and University of Cape Town, Western Cape, South Africa; Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada; Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, and Monash University, Melbourne, Victoria, Australia; The Chinese University of Hong Kong, Hong Kong, China; Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; St. John's Medical College and Research Institute, Bangalore, India; Narayana Hrudayalaya, Bangalore, India; University of North Carolina, Chapel Hill, North Carolina; Schulich School of Medicine & Dentistry at Western University, London, Ontario, Canada; Sant Pau Hospital and Biomedical Research Institute, Autonomous University of Barcelona, Research Center of Cardiovascular Diseases (CIBERCV), Barcelona, Spain; Fundación Cardioinfantil Instituto de Cardiología, Bogotá, and Universidad Autónoma de Bucaramanga, Santander, Colombia; University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy; Medical University of Vienna, Vienna, Austria; Hospital Arzobispo Loayza, Universidad Peruana Cayetano Heredia, Lima, Peru; The University of Texas MD Anderson Cancer Center, Houston, Texas; Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia; CARE Hospitals, Maharanipeta, Visakhapatnam, India; Auckland City Hospital, Auckland, New Zealand; McGill University Health Centre, Montréal, Québec, Canada; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Universitario Fundación Hospital Alcorcon, Madrid, Spain; and Centre Hospitalier Universitaire de Hautepierre, Strasbourg, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>From University of Alberta and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Cleveland Clinic, Cleveland, Ohio; Queen's University, Kingston, Ontario, Canada; Groote Schuur Hospital and University of Cape Town, Western Cape, South Africa; Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada; Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, and Monash University, Melbourne, Victoria, Australia; The Chinese University of Hong Kong, Hong Kong, China; Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; St. John's Medical College and Research Institute, Bangalore, India; Narayana Hrudayalaya, Bangalore, India; University of North Carolina, Chapel Hill, North Carolina; Schulich School of Medicine & Dentistry at Western University, London, Ontario, Canada; Sant Pau Hospital and Biomedical Research Institute, Autonomous University of Barcelona, Research Center of Cardiovascular Diseases (CIBERCV), Barcelona, Spain; Fundación Cardioinfantil Instituto de Cardiología, Bogotá, and Universidad Autónoma de Bucaramanga, Santander, Colombia; University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy; Medical University of Vienna, Vienna, Austria; Hospital Arzobispo Loayza, Universidad Peruana Cayetano Heredia, Lima, Peru; The University of Texas MD Anderson Cancer Center, Houston, Texas; Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia; CARE Hospitals, Maharanipeta, Visakhapatnam, India; Auckland City Hospital, Auckland, New Zealand; McGill University Health Centre, Montréal, Québec, Canada; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Universitario Fundación Hospital Alcorcon, Madrid, Spain; and Centre Hospitalier Universitaire de Hautepierre, Strasbourg</wicri:regionArea><placeName><region type="region">Grand Est</region><region type="old region">Alsace (région administrative)</region><settlement type="city">Strasbourg</settlement></placeName></affiliation></author><author><name sortKey="Villar, Juan Carlos" sort="Villar, Juan Carlos" uniqKey="Villar J" first="Juan Carlos" last="Villar">Juan Carlos Villar</name><affiliation wicri:level="3"><nlm:affiliation>From University of Alberta and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Cleveland Clinic, Cleveland, Ohio; Queen's University, Kingston, Ontario, Canada; Groote Schuur Hospital and University of Cape Town, Western Cape, South Africa; Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada; Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, and Monash University, Melbourne, Victoria, Australia; The Chinese University of Hong Kong, Hong Kong, China; Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; St. John's Medical College and Research Institute, Bangalore, India; Narayana Hrudayalaya, Bangalore, India; University of North Carolina, Chapel Hill, North Carolina; Schulich School of Medicine & Dentistry at Western University, London, Ontario, Canada; Sant Pau Hospital and Biomedical Research Institute, Autonomous University of Barcelona, Research Center of Cardiovascular Diseases (CIBERCV), Barcelona, Spain; Fundación Cardioinfantil Instituto de Cardiología, Bogotá, and Universidad Autónoma de Bucaramanga, Santander, Colombia; University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy; Medical University of Vienna, Vienna, Austria; Hospital Arzobispo Loayza, Universidad Peruana Cayetano Heredia, Lima, Peru; The University of Texas MD Anderson Cancer Center, Houston, Texas; Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia; CARE Hospitals, Maharanipeta, Visakhapatnam, India; Auckland City Hospital, Auckland, New Zealand; McGill University Health Centre, Montréal, Québec, Canada; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Universitario Fundación Hospital Alcorcon, Madrid, Spain; and Centre Hospitalier Universitaire de Hautepierre, Strasbourg, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>From University of Alberta and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Cleveland Clinic, Cleveland, Ohio; Queen's University, Kingston, Ontario, Canada; Groote Schuur Hospital and University of Cape Town, Western Cape, South Africa; Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada; Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, and Monash University, Melbourne, Victoria, Australia; The Chinese University of Hong Kong, Hong Kong, China; Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; St. John's Medical College and Research Institute, Bangalore, India; Narayana Hrudayalaya, Bangalore, India; University of North Carolina, Chapel Hill, North Carolina; Schulich School of Medicine & Dentistry at Western University, London, Ontario, Canada; Sant Pau Hospital and Biomedical Research Institute, Autonomous University of Barcelona, Research Center of Cardiovascular Diseases (CIBERCV), Barcelona, Spain; Fundación Cardioinfantil Instituto de Cardiología, Bogotá, and Universidad Autónoma de Bucaramanga, Santander, Colombia; University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy; Medical University of Vienna, Vienna, Austria; Hospital Arzobispo Loayza, Universidad Peruana Cayetano Heredia, Lima, Peru; The University of Texas MD Anderson Cancer Center, Houston, Texas; Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia; CARE Hospitals, Maharanipeta, Visakhapatnam, India; Auckland City Hospital, Auckland, New Zealand; McGill University Health Centre, Montréal, Québec, Canada; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Universitario Fundación Hospital Alcorcon, Madrid, Spain; and Centre Hospitalier Universitaire de Hautepierre, Strasbourg</wicri:regionArea><placeName><region type="region">Grand Est</region><region type="old region">Alsace (région administrative)</region><settlement type="city">Strasbourg</settlement></placeName></affiliation></author><author><name sortKey="Painter, Thomas W" sort="Painter, Thomas W" uniqKey="Painter T" first="Thomas W" last="Painter">Thomas W. Painter</name><affiliation wicri:level="3"><nlm:affiliation>From University of Alberta and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Cleveland Clinic, Cleveland, Ohio; Queen's University, Kingston, Ontario, Canada; Groote Schuur Hospital and University of Cape Town, Western Cape, South Africa; Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada; Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, and Monash University, Melbourne, Victoria, Australia; The Chinese University of Hong Kong, Hong Kong, China; Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; St. John's Medical College and Research Institute, Bangalore, India; Narayana Hrudayalaya, Bangalore, India; University of North Carolina, Chapel Hill, North Carolina; Schulich School of Medicine & Dentistry at Western University, London, Ontario, Canada; Sant Pau Hospital and Biomedical Research Institute, Autonomous University of Barcelona, Research Center of Cardiovascular Diseases (CIBERCV), Barcelona, Spain; Fundación Cardioinfantil Instituto de Cardiología, Bogotá, and Universidad Autónoma de Bucaramanga, Santander, Colombia; University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy; Medical University of Vienna, Vienna, Austria; Hospital Arzobispo Loayza, Universidad Peruana Cayetano Heredia, Lima, Peru; The University of Texas MD Anderson Cancer Center, Houston, Texas; Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia; CARE Hospitals, Maharanipeta, Visakhapatnam, India; Auckland City Hospital, Auckland, New Zealand; McGill University Health Centre, Montréal, Québec, Canada; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Universitario Fundación Hospital Alcorcon, Madrid, Spain; and Centre Hospitalier Universitaire de Hautepierre, Strasbourg, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>From University of Alberta and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Cleveland Clinic, Cleveland, Ohio; Queen's University, Kingston, Ontario, Canada; Groote Schuur Hospital and University of Cape Town, Western Cape, South Africa; Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada; Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, and Monash University, Melbourne, Victoria, Australia; The Chinese University of Hong Kong, Hong Kong, China; Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; St. John's Medical College and Research Institute, Bangalore, India; Narayana Hrudayalaya, Bangalore, India; University of North Carolina, Chapel Hill, North Carolina; Schulich School of Medicine & Dentistry at Western University, London, Ontario, Canada; Sant Pau Hospital and Biomedical Research Institute, Autonomous University of Barcelona, Research Center of Cardiovascular Diseases (CIBERCV), Barcelona, Spain; Fundación Cardioinfantil Instituto de Cardiología, Bogotá, and Universidad Autónoma de Bucaramanga, Santander, Colombia; University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy; Medical University of Vienna, Vienna, Austria; Hospital Arzobispo Loayza, Universidad Peruana Cayetano Heredia, Lima, Peru; The University of Texas MD Anderson Cancer Center, Houston, Texas; Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia; CARE Hospitals, Maharanipeta, Visakhapatnam, India; Auckland City Hospital, Auckland, New Zealand; McGill University Health Centre, Montréal, Québec, Canada; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Universitario Fundación Hospital Alcorcon, Madrid, Spain; and Centre Hospitalier Universitaire de Hautepierre, Strasbourg</wicri:regionArea><placeName><region type="region">Grand Est</region><region type="old region">Alsace (région administrative)</region><settlement type="city">Strasbourg</settlement></placeName></affiliation></author><author><name sortKey="Landoni, Giovanni" sort="Landoni, Giovanni" uniqKey="Landoni G" first="Giovanni" last="Landoni">Giovanni Landoni</name><affiliation wicri:level="3"><nlm:affiliation>From University of Alberta and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Cleveland Clinic, Cleveland, Ohio; Queen's University, Kingston, Ontario, Canada; Groote Schuur Hospital and University of Cape Town, Western Cape, South Africa; Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada; Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, and Monash University, Melbourne, Victoria, Australia; The Chinese University of Hong Kong, Hong Kong, China; Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; St. John's Medical College and Research Institute, Bangalore, India; Narayana Hrudayalaya, Bangalore, India; University of North Carolina, Chapel Hill, North Carolina; Schulich School of Medicine & Dentistry at Western University, London, Ontario, Canada; Sant Pau Hospital and Biomedical Research Institute, Autonomous University of Barcelona, Research Center of Cardiovascular Diseases (CIBERCV), Barcelona, Spain; Fundación Cardioinfantil Instituto de Cardiología, Bogotá, and Universidad Autónoma de Bucaramanga, Santander, Colombia; University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy; Medical University of Vienna, Vienna, Austria; Hospital Arzobispo Loayza, Universidad Peruana Cayetano Heredia, Lima, Peru; The University of Texas MD Anderson Cancer Center, Houston, Texas; Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia; CARE Hospitals, Maharanipeta, Visakhapatnam, India; Auckland City Hospital, Auckland, New Zealand; McGill University Health Centre, Montréal, Québec, Canada; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Universitario Fundación Hospital Alcorcon, Madrid, Spain; and Centre Hospitalier Universitaire de Hautepierre, Strasbourg, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>From University of Alberta and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Cleveland Clinic, Cleveland, Ohio; Queen's University, Kingston, Ontario, Canada; Groote Schuur Hospital and University of Cape Town, Western Cape, South Africa; Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada; Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, and Monash University, Melbourne, Victoria, Australia; The Chinese University of Hong Kong, Hong Kong, China; Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; St. John's Medical College and Research Institute, Bangalore, India; Narayana Hrudayalaya, Bangalore, India; University of North Carolina, Chapel Hill, North Carolina; Schulich School of Medicine & Dentistry at Western University, London, Ontario, Canada; Sant Pau Hospital and Biomedical Research Institute, Autonomous University of Barcelona, Research Center of Cardiovascular Diseases (CIBERCV), Barcelona, Spain; Fundación Cardioinfantil Instituto de Cardiología, Bogotá, and Universidad Autónoma de Bucaramanga, Santander, Colombia; University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy; Medical University of Vienna, Vienna, Austria; Hospital Arzobispo Loayza, Universidad Peruana Cayetano Heredia, Lima, Peru; The University of Texas MD Anderson Cancer Center, Houston, Texas; Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia; CARE Hospitals, Maharanipeta, Visakhapatnam, India; Auckland City Hospital, Auckland, New Zealand; McGill University Health Centre, Montréal, Québec, Canada; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Universitario Fundación Hospital Alcorcon, Madrid, Spain; and Centre Hospitalier Universitaire de Hautepierre, Strasbourg</wicri:regionArea><placeName><region type="region">Grand Est</region><region type="old region">Alsace (région administrative)</region><settlement type="city">Strasbourg</settlement></placeName></affiliation></author><author><name sortKey="Fleischmann, Edith" sort="Fleischmann, Edith" uniqKey="Fleischmann E" first="Edith" last="Fleischmann">Edith Fleischmann</name><affiliation wicri:level="3"><nlm:affiliation>From University of Alberta and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Cleveland Clinic, Cleveland, Ohio; Queen's University, Kingston, Ontario, Canada; Groote Schuur Hospital and University of Cape Town, Western Cape, South Africa; Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada; Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, and Monash University, Melbourne, Victoria, Australia; The Chinese University of Hong Kong, Hong Kong, China; Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; St. John's Medical College and Research Institute, Bangalore, India; Narayana Hrudayalaya, Bangalore, India; University of North Carolina, Chapel Hill, North Carolina; Schulich School of Medicine & Dentistry at Western University, London, Ontario, Canada; Sant Pau Hospital and Biomedical Research Institute, Autonomous University of Barcelona, Research Center of Cardiovascular Diseases (CIBERCV), Barcelona, Spain; Fundación Cardioinfantil Instituto de Cardiología, Bogotá, and Universidad Autónoma de Bucaramanga, Santander, Colombia; University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy; Medical University of Vienna, Vienna, Austria; Hospital Arzobispo Loayza, Universidad Peruana Cayetano Heredia, Lima, Peru; The University of Texas MD Anderson Cancer Center, Houston, Texas; Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia; CARE Hospitals, Maharanipeta, Visakhapatnam, India; Auckland City Hospital, Auckland, New Zealand; McGill University Health Centre, Montréal, Québec, Canada; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Universitario Fundación Hospital Alcorcon, Madrid, Spain; and Centre Hospitalier Universitaire de Hautepierre, Strasbourg, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>From University of Alberta and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Cleveland Clinic, Cleveland, Ohio; Queen's University, Kingston, Ontario, Canada; Groote Schuur Hospital and University of Cape Town, Western Cape, South Africa; Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada; Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, and Monash University, Melbourne, Victoria, Australia; The Chinese University of Hong Kong, Hong Kong, China; Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; St. John's Medical College and Research Institute, Bangalore, India; Narayana Hrudayalaya, Bangalore, India; University of North Carolina, Chapel Hill, North Carolina; Schulich School of Medicine & Dentistry at Western University, London, Ontario, Canada; Sant Pau Hospital and Biomedical Research Institute, Autonomous University of Barcelona, Research Center of Cardiovascular Diseases (CIBERCV), Barcelona, Spain; Fundación Cardioinfantil Instituto de Cardiología, Bogotá, and Universidad Autónoma de Bucaramanga, Santander, Colombia; University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy; Medical University of Vienna, Vienna, Austria; Hospital Arzobispo Loayza, Universidad Peruana Cayetano Heredia, Lima, Peru; The University of Texas MD Anderson Cancer Center, Houston, Texas; Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia; CARE Hospitals, Maharanipeta, Visakhapatnam, India; Auckland City Hospital, Auckland, New Zealand; McGill University Health Centre, Montréal, Québec, Canada; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Universitario Fundación Hospital Alcorcon, Madrid, Spain; and Centre Hospitalier Universitaire de Hautepierre, Strasbourg</wicri:regionArea><placeName><region type="region">Grand Est</region><region type="old region">Alsace (région administrative)</region><settlement type="city">Strasbourg</settlement></placeName></affiliation></author><author><name sortKey="Lamy, Andre" sort="Lamy, Andre" uniqKey="Lamy A" first="Andre" last="Lamy">Andre Lamy</name><affiliation wicri:level="3"><nlm:affiliation>From University of Alberta and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Cleveland Clinic, Cleveland, Ohio; Queen's University, Kingston, Ontario, Canada; Groote Schuur Hospital and University of Cape Town, Western Cape, South Africa; Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada; Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, and Monash University, Melbourne, Victoria, Australia; The Chinese University of Hong Kong, Hong Kong, China; Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; St. John's Medical College and Research Institute, Bangalore, India; Narayana Hrudayalaya, Bangalore, India; University of North Carolina, Chapel Hill, North Carolina; Schulich School of Medicine & Dentistry at Western University, London, Ontario, Canada; Sant Pau Hospital and Biomedical Research Institute, Autonomous University of Barcelona, Research Center of Cardiovascular Diseases (CIBERCV), Barcelona, Spain; Fundación Cardioinfantil Instituto de Cardiología, Bogotá, and Universidad Autónoma de Bucaramanga, Santander, Colombia; University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy; Medical University of Vienna, Vienna, Austria; Hospital Arzobispo Loayza, Universidad Peruana Cayetano Heredia, Lima, Peru; The University of Texas MD Anderson Cancer Center, Houston, Texas; Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia; CARE Hospitals, Maharanipeta, Visakhapatnam, India; Auckland City Hospital, Auckland, New Zealand; McGill University Health Centre, Montréal, Québec, Canada; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Universitario Fundación Hospital Alcorcon, Madrid, Spain; and Centre Hospitalier Universitaire de Hautepierre, Strasbourg, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>From University of Alberta and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Cleveland Clinic, Cleveland, Ohio; Queen's University, Kingston, Ontario, Canada; Groote Schuur Hospital and University of Cape Town, Western Cape, South Africa; Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada; Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, and Monash University, Melbourne, Victoria, Australia; The Chinese University of Hong Kong, Hong Kong, China; Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; St. John's Medical College and Research Institute, Bangalore, India; Narayana Hrudayalaya, Bangalore, India; University of North Carolina, Chapel Hill, North Carolina; Schulich School of Medicine & Dentistry at Western University, London, Ontario, Canada; Sant Pau Hospital and Biomedical Research Institute, Autonomous University of Barcelona, Research Center of Cardiovascular Diseases (CIBERCV), Barcelona, Spain; Fundación Cardioinfantil Instituto de Cardiología, Bogotá, and Universidad Autónoma de Bucaramanga, Santander, Colombia; University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy; Medical University of Vienna, Vienna, Austria; Hospital Arzobispo Loayza, Universidad Peruana Cayetano Heredia, Lima, Peru; The University of Texas MD Anderson Cancer Center, Houston, Texas; Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia; CARE Hospitals, Maharanipeta, Visakhapatnam, India; Auckland City Hospital, Auckland, New Zealand; McGill University Health Centre, Montréal, Québec, Canada; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Universitario Fundación Hospital Alcorcon, Madrid, Spain; and Centre Hospitalier Universitaire de Hautepierre, Strasbourg</wicri:regionArea><placeName><region type="region">Grand Est</region><region type="old region">Alsace (région administrative)</region><settlement type="city">Strasbourg</settlement></placeName></affiliation></author><author><name sortKey="Whitlock, Richard" sort="Whitlock, Richard" uniqKey="Whitlock R" first="Richard" last="Whitlock">Richard Whitlock</name><affiliation wicri:level="3"><nlm:affiliation>From University of Alberta and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Cleveland Clinic, Cleveland, Ohio; Queen's University, Kingston, Ontario, Canada; Groote Schuur Hospital and University of Cape Town, Western Cape, South Africa; Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada; Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, and Monash University, Melbourne, Victoria, Australia; The Chinese University of Hong Kong, Hong Kong, China; Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; St. John's Medical College and Research Institute, Bangalore, India; Narayana Hrudayalaya, Bangalore, India; University of North Carolina, Chapel Hill, North Carolina; Schulich School of Medicine & Dentistry at Western University, London, Ontario, Canada; Sant Pau Hospital and Biomedical Research Institute, Autonomous University of Barcelona, Research Center of Cardiovascular Diseases (CIBERCV), Barcelona, Spain; Fundación Cardioinfantil Instituto de Cardiología, Bogotá, and Universidad Autónoma de Bucaramanga, Santander, Colombia; University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy; Medical University of Vienna, Vienna, Austria; Hospital Arzobispo Loayza, Universidad Peruana Cayetano Heredia, Lima, Peru; The University of Texas MD Anderson Cancer Center, Houston, Texas; Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia; CARE Hospitals, Maharanipeta, Visakhapatnam, India; Auckland City Hospital, Auckland, New Zealand; McGill University Health Centre, Montréal, Québec, Canada; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Universitario Fundación Hospital Alcorcon, Madrid, Spain; and Centre Hospitalier Universitaire de Hautepierre, Strasbourg, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>From University of Alberta and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Cleveland Clinic, Cleveland, Ohio; Queen's University, Kingston, Ontario, Canada; Groote Schuur Hospital and University of Cape Town, Western Cape, South Africa; Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada; Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, and Monash University, Melbourne, Victoria, Australia; The Chinese University of Hong Kong, Hong Kong, China; Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; St. John's Medical College and Research Institute, Bangalore, India; Narayana Hrudayalaya, Bangalore, India; University of North Carolina, Chapel Hill, North Carolina; Schulich School of Medicine & Dentistry at Western University, London, Ontario, Canada; Sant Pau Hospital and Biomedical Research Institute, Autonomous University of Barcelona, Research Center of Cardiovascular Diseases (CIBERCV), Barcelona, Spain; Fundación Cardioinfantil Instituto de Cardiología, Bogotá, and Universidad Autónoma de Bucaramanga, Santander, Colombia; University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy; Medical University of Vienna, Vienna, Austria; Hospital Arzobispo Loayza, Universidad Peruana Cayetano Heredia, Lima, Peru; The University of Texas MD Anderson Cancer Center, Houston, Texas; Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia; CARE Hospitals, Maharanipeta, Visakhapatnam, India; Auckland City Hospital, Auckland, New Zealand; McGill University Health Centre, Montréal, Québec, Canada; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Universitario Fundación Hospital Alcorcon, Madrid, Spain; and Centre Hospitalier Universitaire de Hautepierre, Strasbourg</wicri:regionArea><placeName><region type="region">Grand Est</region><region type="old region">Alsace (région administrative)</region><settlement type="city">Strasbourg</settlement></placeName></affiliation></author><author><name sortKey="Le Manach, Yannick" sort="Le Manach, Yannick" uniqKey="Le Manach Y" first="Yannick" last="Le Manach">Yannick Le Manach</name><affiliation wicri:level="3"><nlm:affiliation>From University of Alberta and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Cleveland Clinic, Cleveland, Ohio; Queen's University, Kingston, Ontario, Canada; Groote Schuur Hospital and University of Cape Town, Western Cape, South Africa; Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada; Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, and Monash University, Melbourne, Victoria, Australia; The Chinese University of Hong Kong, Hong Kong, China; Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; St. John's Medical College and Research Institute, Bangalore, India; Narayana Hrudayalaya, Bangalore, India; University of North Carolina, Chapel Hill, North Carolina; Schulich School of Medicine & Dentistry at Western University, London, Ontario, Canada; Sant Pau Hospital and Biomedical Research Institute, Autonomous University of Barcelona, Research Center of Cardiovascular Diseases (CIBERCV), Barcelona, Spain; Fundación Cardioinfantil Instituto de Cardiología, Bogotá, and Universidad Autónoma de Bucaramanga, Santander, Colombia; University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy; Medical University of Vienna, Vienna, Austria; Hospital Arzobispo Loayza, Universidad Peruana Cayetano Heredia, Lima, Peru; The University of Texas MD Anderson Cancer Center, Houston, Texas; Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia; CARE Hospitals, Maharanipeta, Visakhapatnam, India; Auckland City Hospital, Auckland, New Zealand; McGill University Health Centre, Montréal, Québec, Canada; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Universitario Fundación Hospital Alcorcon, Madrid, Spain; and Centre Hospitalier Universitaire de Hautepierre, Strasbourg, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>From University of Alberta and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Cleveland Clinic, Cleveland, Ohio; Queen's University, Kingston, Ontario, Canada; Groote Schuur Hospital and University of Cape Town, Western Cape, South Africa; Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada; Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, and Monash University, Melbourne, Victoria, Australia; The Chinese University of Hong Kong, Hong Kong, China; Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; St. John's Medical College and Research Institute, Bangalore, India; Narayana Hrudayalaya, Bangalore, India; University of North Carolina, Chapel Hill, North Carolina; Schulich School of Medicine & Dentistry at Western University, London, Ontario, Canada; Sant Pau Hospital and Biomedical Research Institute, Autonomous University of Barcelona, Research Center of Cardiovascular Diseases (CIBERCV), Barcelona, Spain; Fundación Cardioinfantil Instituto de Cardiología, Bogotá, and Universidad Autónoma de Bucaramanga, Santander, Colombia; University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy; Medical University of Vienna, Vienna, Austria; Hospital Arzobispo Loayza, Universidad Peruana Cayetano Heredia, Lima, Peru; The University of Texas MD Anderson Cancer Center, Houston, Texas; Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia; CARE Hospitals, Maharanipeta, Visakhapatnam, India; Auckland City Hospital, Auckland, New Zealand; McGill University Health Centre, Montréal, Québec, Canada; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Universitario Fundación Hospital Alcorcon, Madrid, Spain; and Centre Hospitalier Universitaire de Hautepierre, Strasbourg</wicri:regionArea><placeName><region type="region">Grand Est</region><region type="old region">Alsace (région administrative)</region><settlement type="city">Strasbourg</settlement></placeName></affiliation></author><author><name sortKey="Aphang Lam, Meylin" sort="Aphang Lam, Meylin" uniqKey="Aphang Lam M" first="Meylin" last="Aphang-Lam">Meylin Aphang-Lam</name><affiliation wicri:level="3"><nlm:affiliation>From University of Alberta and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Cleveland Clinic, Cleveland, Ohio; Queen's University, Kingston, Ontario, Canada; Groote Schuur Hospital and University of Cape Town, Western Cape, South Africa; Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada; Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, and Monash University, Melbourne, Victoria, Australia; The Chinese University of Hong Kong, Hong Kong, China; Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; St. John's Medical College and Research Institute, Bangalore, India; Narayana Hrudayalaya, Bangalore, India; University of North Carolina, Chapel Hill, North Carolina; Schulich School of Medicine & Dentistry at Western University, London, Ontario, Canada; Sant Pau Hospital and Biomedical Research Institute, Autonomous University of Barcelona, Research Center of Cardiovascular Diseases (CIBERCV), Barcelona, Spain; Fundación Cardioinfantil Instituto de Cardiología, Bogotá, and Universidad Autónoma de Bucaramanga, Santander, Colombia; University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy; Medical University of Vienna, Vienna, Austria; Hospital Arzobispo Loayza, Universidad Peruana Cayetano Heredia, Lima, Peru; The University of Texas MD Anderson Cancer Center, Houston, Texas; Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia; CARE Hospitals, Maharanipeta, Visakhapatnam, India; Auckland City Hospital, Auckland, New Zealand; McGill University Health Centre, Montréal, Québec, Canada; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Universitario Fundación Hospital Alcorcon, Madrid, Spain; and Centre Hospitalier Universitaire de Hautepierre, Strasbourg, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>From University of Alberta and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Cleveland Clinic, Cleveland, Ohio; Queen's University, Kingston, Ontario, Canada; Groote Schuur Hospital and University of Cape Town, Western Cape, South Africa; Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada; Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, and Monash University, Melbourne, Victoria, Australia; The Chinese University of Hong Kong, Hong Kong, China; Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; St. John's Medical College and Research Institute, Bangalore, India; Narayana Hrudayalaya, Bangalore, India; University of North Carolina, Chapel Hill, North Carolina; Schulich School of Medicine & Dentistry at Western University, London, Ontario, Canada; Sant Pau Hospital and Biomedical Research Institute, Autonomous University of Barcelona, Research Center of Cardiovascular Diseases (CIBERCV), Barcelona, Spain; Fundación Cardioinfantil Instituto de Cardiología, Bogotá, and Universidad Autónoma de Bucaramanga, Santander, Colombia; University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy; Medical University of Vienna, Vienna, Austria; Hospital Arzobispo Loayza, Universidad Peruana Cayetano Heredia, Lima, Peru; The University of Texas MD Anderson Cancer Center, Houston, Texas; Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia; CARE Hospitals, Maharanipeta, Visakhapatnam, India; Auckland City Hospital, Auckland, New Zealand; McGill University Health Centre, Montréal, Québec, Canada; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Universitario Fundación Hospital Alcorcon, Madrid, Spain; and Centre Hospitalier Universitaire de Hautepierre, Strasbourg</wicri:regionArea><placeName><region type="region">Grand Est</region><region type="old region">Alsace (région administrative)</region><settlement type="city">Strasbourg</settlement></placeName></affiliation></author><author><name sortKey="Cata, Juan P" sort="Cata, Juan P" uniqKey="Cata J" first="Juan P" last="Cata">Juan P. Cata</name><affiliation wicri:level="3"><nlm:affiliation>From University of Alberta and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Cleveland Clinic, Cleveland, Ohio; Queen's University, Kingston, Ontario, Canada; Groote Schuur Hospital and University of Cape Town, Western Cape, South Africa; Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada; Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, and Monash University, Melbourne, Victoria, Australia; The Chinese University of Hong Kong, Hong Kong, China; Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; St. John's Medical College and Research Institute, Bangalore, India; Narayana Hrudayalaya, Bangalore, India; University of North Carolina, Chapel Hill, North Carolina; Schulich School of Medicine & Dentistry at Western University, London, Ontario, Canada; Sant Pau Hospital and Biomedical Research Institute, Autonomous University of Barcelona, Research Center of Cardiovascular Diseases (CIBERCV), Barcelona, Spain; Fundación Cardioinfantil Instituto de Cardiología, Bogotá, and Universidad Autónoma de Bucaramanga, Santander, Colombia; University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy; Medical University of Vienna, Vienna, Austria; Hospital Arzobispo Loayza, Universidad Peruana Cayetano Heredia, Lima, Peru; The University of Texas MD Anderson Cancer Center, Houston, Texas; Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia; CARE Hospitals, Maharanipeta, Visakhapatnam, India; Auckland City Hospital, Auckland, New Zealand; McGill University Health Centre, Montréal, Québec, Canada; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Universitario Fundación Hospital Alcorcon, Madrid, Spain; and Centre Hospitalier Universitaire de Hautepierre, Strasbourg, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>From University of Alberta and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Cleveland Clinic, Cleveland, Ohio; Queen's University, Kingston, Ontario, Canada; Groote Schuur Hospital and University of Cape Town, Western Cape, South Africa; Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada; Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, and Monash University, Melbourne, Victoria, Australia; The Chinese University of Hong Kong, Hong Kong, China; Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; St. John's Medical College and Research Institute, Bangalore, India; Narayana Hrudayalaya, Bangalore, India; University of North Carolina, Chapel Hill, North Carolina; Schulich School of Medicine & Dentistry at Western University, London, Ontario, Canada; Sant Pau Hospital and Biomedical Research Institute, Autonomous University of Barcelona, Research Center of Cardiovascular Diseases (CIBERCV), Barcelona, Spain; Fundación Cardioinfantil Instituto de Cardiología, Bogotá, and Universidad Autónoma de Bucaramanga, Santander, Colombia; University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy; Medical University of Vienna, Vienna, Austria; Hospital Arzobispo Loayza, Universidad Peruana Cayetano Heredia, Lima, Peru; The University of Texas MD Anderson Cancer Center, Houston, Texas; Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia; CARE Hospitals, Maharanipeta, Visakhapatnam, India; Auckland City Hospital, Auckland, New Zealand; McGill University Health Centre, Montréal, Québec, Canada; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Universitario Fundación Hospital Alcorcon, Madrid, Spain; and Centre Hospitalier Universitaire de Hautepierre, Strasbourg</wicri:regionArea><placeName><region type="region">Grand Est</region><region type="old region">Alsace (région administrative)</region><settlement type="city">Strasbourg</settlement></placeName></affiliation></author><author><name sortKey="Gao, Peggy" sort="Gao, Peggy" uniqKey="Gao P" first="Peggy" last="Gao">Peggy Gao</name><affiliation wicri:level="3"><nlm:affiliation>From University of Alberta and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Cleveland Clinic, Cleveland, Ohio; Queen's University, Kingston, Ontario, Canada; Groote Schuur Hospital and University of Cape Town, Western Cape, South Africa; Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada; Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, and Monash University, Melbourne, Victoria, Australia; The Chinese University of Hong Kong, Hong Kong, China; Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; St. John's Medical College and Research Institute, Bangalore, India; Narayana Hrudayalaya, Bangalore, India; University of North Carolina, Chapel Hill, North Carolina; Schulich School of Medicine & Dentistry at Western University, London, Ontario, Canada; Sant Pau Hospital and Biomedical Research Institute, Autonomous University of Barcelona, Research Center of Cardiovascular Diseases (CIBERCV), Barcelona, Spain; Fundación Cardioinfantil Instituto de Cardiología, Bogotá, and Universidad Autónoma de Bucaramanga, Santander, Colombia; University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy; Medical University of Vienna, Vienna, Austria; Hospital Arzobispo Loayza, Universidad Peruana Cayetano Heredia, Lima, Peru; The University of Texas MD Anderson Cancer Center, Houston, Texas; Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia; CARE Hospitals, Maharanipeta, Visakhapatnam, India; Auckland City Hospital, Auckland, New Zealand; McGill University Health Centre, Montréal, Québec, Canada; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Universitario Fundación Hospital Alcorcon, Madrid, Spain; and Centre Hospitalier Universitaire de Hautepierre, Strasbourg, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>From University of Alberta and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Cleveland Clinic, Cleveland, Ohio; Queen's University, Kingston, Ontario, Canada; Groote Schuur Hospital and University of Cape Town, Western Cape, South Africa; Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada; Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, and Monash University, Melbourne, Victoria, Australia; The Chinese University of Hong Kong, Hong Kong, China; Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; St. John's Medical College and Research Institute, Bangalore, India; Narayana Hrudayalaya, Bangalore, India; University of North Carolina, Chapel Hill, North Carolina; Schulich School of Medicine & Dentistry at Western University, London, Ontario, Canada; Sant Pau Hospital and Biomedical Research Institute, Autonomous University of Barcelona, Research Center of Cardiovascular Diseases (CIBERCV), Barcelona, Spain; Fundación Cardioinfantil Instituto de Cardiología, Bogotá, and Universidad Autónoma de Bucaramanga, Santander, Colombia; University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy; Medical University of Vienna, Vienna, Austria; Hospital Arzobispo Loayza, Universidad Peruana Cayetano Heredia, Lima, Peru; The University of Texas MD Anderson Cancer Center, Houston, Texas; Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia; CARE Hospitals, Maharanipeta, Visakhapatnam, India; Auckland City Hospital, Auckland, New Zealand; McGill University Health Centre, Montréal, Québec, Canada; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Universitario Fundación Hospital Alcorcon, Madrid, Spain; and Centre Hospitalier Universitaire de Hautepierre, Strasbourg</wicri:regionArea><placeName><region type="region">Grand Est</region><region type="old region">Alsace (région administrative)</region><settlement type="city">Strasbourg</settlement></placeName></affiliation></author><author><name sortKey="Terblanche, Nicolaas C S" sort="Terblanche, Nicolaas C S" uniqKey="Terblanche N" first="Nicolaas C S" last="Terblanche">Nicolaas C S. Terblanche</name><affiliation wicri:level="3"><nlm:affiliation>From University of Alberta and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Cleveland Clinic, Cleveland, Ohio; Queen's University, Kingston, Ontario, Canada; Groote Schuur Hospital and University of Cape Town, Western Cape, South Africa; Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada; Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, and Monash University, Melbourne, Victoria, Australia; The Chinese University of Hong Kong, Hong Kong, China; Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; St. John's Medical College and Research Institute, Bangalore, India; Narayana Hrudayalaya, Bangalore, India; University of North Carolina, Chapel Hill, North Carolina; Schulich School of Medicine & Dentistry at Western University, London, Ontario, Canada; Sant Pau Hospital and Biomedical Research Institute, Autonomous University of Barcelona, Research Center of Cardiovascular Diseases (CIBERCV), Barcelona, Spain; Fundación Cardioinfantil Instituto de Cardiología, Bogotá, and Universidad Autónoma de Bucaramanga, Santander, Colombia; University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy; Medical University of Vienna, Vienna, Austria; Hospital Arzobispo Loayza, Universidad Peruana Cayetano Heredia, Lima, Peru; The University of Texas MD Anderson Cancer Center, Houston, Texas; Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia; CARE Hospitals, Maharanipeta, Visakhapatnam, India; Auckland City Hospital, Auckland, New Zealand; McGill University Health Centre, Montréal, Québec, Canada; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Universitario Fundación Hospital Alcorcon, Madrid, Spain; and Centre Hospitalier Universitaire de Hautepierre, Strasbourg, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>From University of Alberta and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Cleveland Clinic, Cleveland, Ohio; Queen's University, Kingston, Ontario, Canada; Groote Schuur Hospital and University of Cape Town, Western Cape, South Africa; Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada; Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, and Monash University, Melbourne, Victoria, Australia; The Chinese University of Hong Kong, Hong Kong, China; Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; St. John's Medical College and Research Institute, Bangalore, India; Narayana Hrudayalaya, Bangalore, India; University of North Carolina, Chapel Hill, North Carolina; Schulich School of Medicine & Dentistry at Western University, London, Ontario, Canada; Sant Pau Hospital and Biomedical Research Institute, Autonomous University of Barcelona, Research Center of Cardiovascular Diseases (CIBERCV), Barcelona, Spain; Fundación Cardioinfantil Instituto de Cardiología, Bogotá, and Universidad Autónoma de Bucaramanga, Santander, Colombia; University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy; Medical University of Vienna, Vienna, Austria; Hospital Arzobispo Loayza, Universidad Peruana Cayetano Heredia, Lima, Peru; The University of Texas MD Anderson Cancer Center, Houston, Texas; Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia; CARE Hospitals, Maharanipeta, Visakhapatnam, India; Auckland City Hospital, Auckland, New Zealand; McGill University Health Centre, Montréal, Québec, Canada; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Universitario Fundación Hospital Alcorcon, Madrid, Spain; and Centre Hospitalier Universitaire de Hautepierre, Strasbourg</wicri:regionArea><placeName><region type="region">Grand Est</region><region type="old region">Alsace (région administrative)</region><settlement type="city">Strasbourg</settlement></placeName></affiliation></author><author><name sortKey="Ramana, Pamidimukkala V" sort="Ramana, Pamidimukkala V" uniqKey="Ramana P" first="Pamidimukkala V" last="Ramana">Pamidimukkala V. Ramana</name><affiliation wicri:level="3"><nlm:affiliation>From University of Alberta and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Cleveland Clinic, Cleveland, Ohio; Queen's University, Kingston, Ontario, Canada; Groote Schuur Hospital and University of Cape Town, Western Cape, South Africa; Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada; Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, and Monash University, Melbourne, Victoria, Australia; The Chinese University of Hong Kong, Hong Kong, China; Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; St. John's Medical College and Research Institute, Bangalore, India; Narayana Hrudayalaya, Bangalore, India; University of North Carolina, Chapel Hill, North Carolina; Schulich School of Medicine & Dentistry at Western University, London, Ontario, Canada; Sant Pau Hospital and Biomedical Research Institute, Autonomous University of Barcelona, Research Center of Cardiovascular Diseases (CIBERCV), Barcelona, Spain; Fundación Cardioinfantil Instituto de Cardiología, Bogotá, and Universidad Autónoma de Bucaramanga, Santander, Colombia; University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy; Medical University of Vienna, Vienna, Austria; Hospital Arzobispo Loayza, Universidad Peruana Cayetano Heredia, Lima, Peru; The University of Texas MD Anderson Cancer Center, Houston, Texas; Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia; CARE Hospitals, Maharanipeta, Visakhapatnam, India; Auckland City Hospital, Auckland, New Zealand; McGill University Health Centre, Montréal, Québec, Canada; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Universitario Fundación Hospital Alcorcon, Madrid, Spain; and Centre Hospitalier Universitaire de Hautepierre, Strasbourg, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>From University of Alberta and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Cleveland Clinic, Cleveland, Ohio; Queen's University, Kingston, Ontario, Canada; Groote Schuur Hospital and University of Cape Town, Western Cape, South Africa; Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada; Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, and Monash University, Melbourne, Victoria, Australia; The Chinese University of Hong Kong, Hong Kong, China; Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; St. John's Medical College and Research Institute, Bangalore, India; Narayana Hrudayalaya, Bangalore, India; University of North Carolina, Chapel Hill, North Carolina; Schulich School of Medicine & Dentistry at Western University, London, Ontario, Canada; Sant Pau Hospital and Biomedical Research Institute, Autonomous University of Barcelona, Research Center of Cardiovascular Diseases (CIBERCV), Barcelona, Spain; Fundación Cardioinfantil Instituto de Cardiología, Bogotá, and Universidad Autónoma de Bucaramanga, Santander, Colombia; University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy; Medical University of Vienna, Vienna, Austria; Hospital Arzobispo Loayza, Universidad Peruana Cayetano Heredia, Lima, Peru; The University of Texas MD Anderson Cancer Center, Houston, Texas; Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia; CARE Hospitals, Maharanipeta, Visakhapatnam, India; Auckland City Hospital, Auckland, New Zealand; McGill University Health Centre, Montréal, Québec, Canada; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Universitario Fundación Hospital Alcorcon, Madrid, Spain; and Centre Hospitalier Universitaire de Hautepierre, Strasbourg</wicri:regionArea><placeName><region type="region">Grand Est</region><region type="old region">Alsace (région administrative)</region><settlement type="city">Strasbourg</settlement></placeName></affiliation></author><author><name sortKey="Jamieson, Kim A" sort="Jamieson, Kim A" uniqKey="Jamieson K" first="Kim A" last="Jamieson">Kim A. Jamieson</name><affiliation wicri:level="3"><nlm:affiliation>From University of Alberta and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Cleveland Clinic, Cleveland, Ohio; Queen's University, Kingston, Ontario, Canada; Groote Schuur Hospital and University of Cape Town, Western Cape, South Africa; Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada; Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, and Monash University, Melbourne, Victoria, Australia; The Chinese University of Hong Kong, Hong Kong, China; Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; St. John's Medical College and Research Institute, Bangalore, India; Narayana Hrudayalaya, Bangalore, India; University of North Carolina, Chapel Hill, North Carolina; Schulich School of Medicine & Dentistry at Western University, London, Ontario, Canada; Sant Pau Hospital and Biomedical Research Institute, Autonomous University of Barcelona, Research Center of Cardiovascular Diseases (CIBERCV), Barcelona, Spain; Fundación Cardioinfantil Instituto de Cardiología, Bogotá, and Universidad Autónoma de Bucaramanga, Santander, Colombia; University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy; Medical University of Vienna, Vienna, Austria; Hospital Arzobispo Loayza, Universidad Peruana Cayetano Heredia, Lima, Peru; The University of Texas MD Anderson Cancer Center, Houston, Texas; Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia; CARE Hospitals, Maharanipeta, Visakhapatnam, India; Auckland City Hospital, Auckland, New Zealand; McGill University Health Centre, Montréal, Québec, Canada; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Universitario Fundación Hospital Alcorcon, Madrid, Spain; and Centre Hospitalier Universitaire de Hautepierre, Strasbourg, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>From University of Alberta and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Cleveland Clinic, Cleveland, Ohio; Queen's University, Kingston, Ontario, Canada; Groote Schuur Hospital and University of Cape Town, Western Cape, South Africa; Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada; Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, and Monash University, Melbourne, Victoria, Australia; The Chinese University of Hong Kong, Hong Kong, China; Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; St. John's Medical College and Research Institute, Bangalore, India; Narayana Hrudayalaya, Bangalore, India; University of North Carolina, Chapel Hill, North Carolina; Schulich School of Medicine & Dentistry at Western University, London, Ontario, Canada; Sant Pau Hospital and Biomedical Research Institute, Autonomous University of Barcelona, Research Center of Cardiovascular Diseases (CIBERCV), Barcelona, Spain; Fundación Cardioinfantil Instituto de Cardiología, Bogotá, and Universidad Autónoma de Bucaramanga, Santander, Colombia; University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy; Medical University of Vienna, Vienna, Austria; Hospital Arzobispo Loayza, Universidad Peruana Cayetano Heredia, Lima, Peru; The University of Texas MD Anderson Cancer Center, Houston, Texas; Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia; CARE Hospitals, Maharanipeta, Visakhapatnam, India; Auckland City Hospital, Auckland, New Zealand; McGill University Health Centre, Montréal, Québec, Canada; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Universitario Fundación Hospital Alcorcon, Madrid, Spain; and Centre Hospitalier Universitaire de Hautepierre, Strasbourg</wicri:regionArea><placeName><region type="region">Grand Est</region><region type="old region">Alsace (région administrative)</region><settlement type="city">Strasbourg</settlement></placeName></affiliation></author><author><name sortKey="Bessissow, Amal" sort="Bessissow, Amal" uniqKey="Bessissow A" first="Amal" last="Bessissow">Amal Bessissow</name><affiliation wicri:level="3"><nlm:affiliation>From University of Alberta and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Cleveland Clinic, Cleveland, Ohio; Queen's University, Kingston, Ontario, Canada; Groote Schuur Hospital and University of Cape Town, Western Cape, South Africa; Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada; Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, and Monash University, Melbourne, Victoria, Australia; The Chinese University of Hong Kong, Hong Kong, China; Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; St. John's Medical College and Research Institute, Bangalore, India; Narayana Hrudayalaya, Bangalore, India; University of North Carolina, Chapel Hill, North Carolina; Schulich School of Medicine & Dentistry at Western University, London, Ontario, Canada; Sant Pau Hospital and Biomedical Research Institute, Autonomous University of Barcelona, Research Center of Cardiovascular Diseases (CIBERCV), Barcelona, Spain; Fundación Cardioinfantil Instituto de Cardiología, Bogotá, and Universidad Autónoma de Bucaramanga, Santander, Colombia; University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy; Medical University of Vienna, Vienna, Austria; Hospital Arzobispo Loayza, Universidad Peruana Cayetano Heredia, Lima, Peru; The University of Texas MD Anderson Cancer Center, Houston, Texas; Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia; CARE Hospitals, Maharanipeta, Visakhapatnam, India; Auckland City Hospital, Auckland, New Zealand; McGill University Health Centre, Montréal, Québec, Canada; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Universitario Fundación Hospital Alcorcon, Madrid, Spain; and Centre Hospitalier Universitaire de Hautepierre, Strasbourg, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>From University of Alberta and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Cleveland Clinic, Cleveland, Ohio; Queen's University, Kingston, Ontario, Canada; Groote Schuur Hospital and University of Cape Town, Western Cape, South Africa; Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada; Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, and Monash University, Melbourne, Victoria, Australia; The Chinese University of Hong Kong, Hong Kong, China; Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; St. John's Medical College and Research Institute, Bangalore, India; Narayana Hrudayalaya, Bangalore, India; University of North Carolina, Chapel Hill, North Carolina; Schulich School of Medicine & Dentistry at Western University, London, Ontario, Canada; Sant Pau Hospital and Biomedical Research Institute, Autonomous University of Barcelona, Research Center of Cardiovascular Diseases (CIBERCV), Barcelona, Spain; Fundación Cardioinfantil Instituto de Cardiología, Bogotá, and Universidad Autónoma de Bucaramanga, Santander, Colombia; University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy; Medical University of Vienna, Vienna, Austria; Hospital Arzobispo Loayza, Universidad Peruana Cayetano Heredia, Lima, Peru; The University of Texas MD Anderson Cancer Center, Houston, Texas; Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia; CARE Hospitals, Maharanipeta, Visakhapatnam, India; Auckland City Hospital, Auckland, New Zealand; McGill University Health Centre, Montréal, Québec, Canada; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Universitario Fundación Hospital Alcorcon, Madrid, Spain; and Centre Hospitalier Universitaire de Hautepierre, Strasbourg</wicri:regionArea><placeName><region type="region">Grand Est</region><region type="old region">Alsace (région administrative)</region><settlement type="city">Strasbourg</settlement></placeName></affiliation></author><author><name sortKey="Mendoza, Gabriela R" sort="Mendoza, Gabriela R" uniqKey="Mendoza G" first="Gabriela R" last="Mendoza">Gabriela R. Mendoza</name><affiliation wicri:level="3"><nlm:affiliation>From University of Alberta and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Cleveland Clinic, Cleveland, Ohio; Queen's University, Kingston, Ontario, Canada; Groote Schuur Hospital and University of Cape Town, Western Cape, South Africa; Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada; Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, and Monash University, Melbourne, Victoria, Australia; The Chinese University of Hong Kong, Hong Kong, China; Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; St. John's Medical College and Research Institute, Bangalore, India; Narayana Hrudayalaya, Bangalore, India; University of North Carolina, Chapel Hill, North Carolina; Schulich School of Medicine & Dentistry at Western University, London, Ontario, Canada; Sant Pau Hospital and Biomedical Research Institute, Autonomous University of Barcelona, Research Center of Cardiovascular Diseases (CIBERCV), Barcelona, Spain; Fundación Cardioinfantil Instituto de Cardiología, Bogotá, and Universidad Autónoma de Bucaramanga, Santander, Colombia; University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy; Medical University of Vienna, Vienna, Austria; Hospital Arzobispo Loayza, Universidad Peruana Cayetano Heredia, Lima, Peru; The University of Texas MD Anderson Cancer Center, Houston, Texas; Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia; CARE Hospitals, Maharanipeta, Visakhapatnam, India; Auckland City Hospital, Auckland, New Zealand; McGill University Health Centre, Montréal, Québec, Canada; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Universitario Fundación Hospital Alcorcon, Madrid, Spain; and Centre Hospitalier Universitaire de Hautepierre, Strasbourg, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>From University of Alberta and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Cleveland Clinic, Cleveland, Ohio; Queen's University, Kingston, Ontario, Canada; Groote Schuur Hospital and University of Cape Town, Western Cape, South Africa; Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada; Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, and Monash University, Melbourne, Victoria, Australia; The Chinese University of Hong Kong, Hong Kong, China; Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; St. John's Medical College and Research Institute, Bangalore, India; Narayana Hrudayalaya, Bangalore, India; University of North Carolina, Chapel Hill, North Carolina; Schulich School of Medicine & Dentistry at Western University, London, Ontario, Canada; Sant Pau Hospital and Biomedical Research Institute, Autonomous University of Barcelona, Research Center of Cardiovascular Diseases (CIBERCV), Barcelona, Spain; Fundación Cardioinfantil Instituto de Cardiología, Bogotá, and Universidad Autónoma de Bucaramanga, Santander, Colombia; University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy; Medical University of Vienna, Vienna, Austria; Hospital Arzobispo Loayza, Universidad Peruana Cayetano Heredia, Lima, Peru; The University of Texas MD Anderson Cancer Center, Houston, Texas; Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia; CARE Hospitals, Maharanipeta, Visakhapatnam, India; Auckland City Hospital, Auckland, New Zealand; McGill University Health Centre, Montréal, Québec, Canada; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Universitario Fundación Hospital Alcorcon, Madrid, Spain; and Centre Hospitalier Universitaire de Hautepierre, Strasbourg</wicri:regionArea><placeName><region type="region">Grand Est</region><region type="old region">Alsace (région administrative)</region><settlement type="city">Strasbourg</settlement></placeName></affiliation></author><author><name sortKey="Ramirez, Silvia" sort="Ramirez, Silvia" uniqKey="Ramirez S" first="Silvia" last="Ramirez">Silvia Ramirez</name><affiliation wicri:level="3"><nlm:affiliation>From University of Alberta and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Cleveland Clinic, Cleveland, Ohio; Queen's University, Kingston, Ontario, Canada; Groote Schuur Hospital and University of Cape Town, Western Cape, South Africa; Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada; Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, and Monash University, Melbourne, Victoria, Australia; The Chinese University of Hong Kong, Hong Kong, China; Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; St. John's Medical College and Research Institute, Bangalore, India; Narayana Hrudayalaya, Bangalore, India; University of North Carolina, Chapel Hill, North Carolina; Schulich School of Medicine & Dentistry at Western University, London, Ontario, Canada; Sant Pau Hospital and Biomedical Research Institute, Autonomous University of Barcelona, Research Center of Cardiovascular Diseases (CIBERCV), Barcelona, Spain; Fundación Cardioinfantil Instituto de Cardiología, Bogotá, and Universidad Autónoma de Bucaramanga, Santander, Colombia; University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy; Medical University of Vienna, Vienna, Austria; Hospital Arzobispo Loayza, Universidad Peruana Cayetano Heredia, Lima, Peru; The University of Texas MD Anderson Cancer Center, Houston, Texas; Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia; CARE Hospitals, Maharanipeta, Visakhapatnam, India; Auckland City Hospital, Auckland, New Zealand; McGill University Health Centre, Montréal, Québec, Canada; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Universitario Fundación Hospital Alcorcon, Madrid, Spain; and Centre Hospitalier Universitaire de Hautepierre, Strasbourg, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>From University of Alberta and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Cleveland Clinic, Cleveland, Ohio; Queen's University, Kingston, Ontario, Canada; Groote Schuur Hospital and University of Cape Town, Western Cape, South Africa; Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada; Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, and Monash University, Melbourne, Victoria, Australia; The Chinese University of Hong Kong, Hong Kong, China; Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; St. John's Medical College and Research Institute, Bangalore, India; Narayana Hrudayalaya, Bangalore, India; University of North Carolina, Chapel Hill, North Carolina; Schulich School of Medicine & Dentistry at Western University, London, Ontario, Canada; Sant Pau Hospital and Biomedical Research Institute, Autonomous University of Barcelona, Research Center of Cardiovascular Diseases (CIBERCV), Barcelona, Spain; Fundación Cardioinfantil Instituto de Cardiología, Bogotá, and Universidad Autónoma de Bucaramanga, Santander, Colombia; University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy; Medical University of Vienna, Vienna, Austria; Hospital Arzobispo Loayza, Universidad Peruana Cayetano Heredia, Lima, Peru; The University of Texas MD Anderson Cancer Center, Houston, Texas; Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia; CARE Hospitals, Maharanipeta, Visakhapatnam, India; Auckland City Hospital, Auckland, New Zealand; McGill University Health Centre, Montréal, Québec, Canada; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Universitario Fundación Hospital Alcorcon, Madrid, Spain; and Centre Hospitalier Universitaire de Hautepierre, Strasbourg</wicri:regionArea><placeName><region type="region">Grand Est</region><region type="old region">Alsace (région administrative)</region><settlement type="city">Strasbourg</settlement></placeName></affiliation></author><author><name sortKey="Diemunsch, Pierre A" sort="Diemunsch, Pierre A" uniqKey="Diemunsch P" first="Pierre A" last="Diemunsch">Pierre A. Diemunsch</name><affiliation wicri:level="3"><nlm:affiliation>From University of Alberta and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Cleveland Clinic, Cleveland, Ohio; Queen's University, Kingston, Ontario, Canada; Groote Schuur Hospital and University of Cape Town, Western Cape, South Africa; Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada; Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, and Monash University, Melbourne, Victoria, Australia; The Chinese University of Hong Kong, Hong Kong, China; Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; St. John's Medical College and Research Institute, Bangalore, India; Narayana Hrudayalaya, Bangalore, India; University of North Carolina, Chapel Hill, North Carolina; Schulich School of Medicine & Dentistry at Western University, London, Ontario, Canada; Sant Pau Hospital and Biomedical Research Institute, Autonomous University of Barcelona, Research Center of Cardiovascular Diseases (CIBERCV), Barcelona, Spain; Fundación Cardioinfantil Instituto de Cardiología, Bogotá, and Universidad Autónoma de Bucaramanga, Santander, Colombia; University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy; Medical University of Vienna, Vienna, Austria; Hospital Arzobispo Loayza, Universidad Peruana Cayetano Heredia, Lima, Peru; The University of Texas MD Anderson Cancer Center, Houston, Texas; Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia; CARE Hospitals, Maharanipeta, Visakhapatnam, India; Auckland City Hospital, Auckland, New Zealand; McGill University Health Centre, Montréal, Québec, Canada; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Universitario Fundación Hospital Alcorcon, Madrid, Spain; and Centre Hospitalier Universitaire de Hautepierre, Strasbourg, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>From University of Alberta and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Cleveland Clinic, Cleveland, Ohio; Queen's University, Kingston, Ontario, Canada; Groote Schuur Hospital and University of Cape Town, Western Cape, South Africa; Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada; Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, and Monash University, Melbourne, Victoria, Australia; The Chinese University of Hong Kong, Hong Kong, China; Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; St. John's Medical College and Research Institute, Bangalore, India; Narayana Hrudayalaya, Bangalore, India; University of North Carolina, Chapel Hill, North Carolina; Schulich School of Medicine & Dentistry at Western University, London, Ontario, Canada; Sant Pau Hospital and Biomedical Research Institute, Autonomous University of Barcelona, Research Center of Cardiovascular Diseases (CIBERCV), Barcelona, Spain; Fundación Cardioinfantil Instituto de Cardiología, Bogotá, and Universidad Autónoma de Bucaramanga, Santander, Colombia; University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy; Medical University of Vienna, Vienna, Austria; Hospital Arzobispo Loayza, Universidad Peruana Cayetano Heredia, Lima, Peru; The University of Texas MD Anderson Cancer Center, Houston, Texas; Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia; CARE Hospitals, Maharanipeta, Visakhapatnam, India; Auckland City Hospital, Auckland, New Zealand; McGill University Health Centre, Montréal, Québec, Canada; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Universitario Fundación Hospital Alcorcon, Madrid, Spain; and Centre Hospitalier Universitaire de Hautepierre, Strasbourg</wicri:regionArea><placeName><region type="region">Grand Est</region><region type="old region">Alsace (région administrative)</region><settlement type="city">Strasbourg</settlement></placeName></affiliation></author><author><name sortKey="Yusuf, Salim" sort="Yusuf, Salim" uniqKey="Yusuf S" first="Salim" last="Yusuf">Salim Yusuf</name><affiliation wicri:level="3"><nlm:affiliation>From University of Alberta and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Cleveland Clinic, Cleveland, Ohio; Queen's University, Kingston, Ontario, Canada; Groote Schuur Hospital and University of Cape Town, Western Cape, South Africa; Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada; Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, and Monash University, Melbourne, Victoria, Australia; The Chinese University of Hong Kong, Hong Kong, China; Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; St. John's Medical College and Research Institute, Bangalore, India; Narayana Hrudayalaya, Bangalore, India; University of North Carolina, Chapel Hill, North Carolina; Schulich School of Medicine & Dentistry at Western University, London, Ontario, Canada; Sant Pau Hospital and Biomedical Research Institute, Autonomous University of Barcelona, Research Center of Cardiovascular Diseases (CIBERCV), Barcelona, Spain; Fundación Cardioinfantil Instituto de Cardiología, Bogotá, and Universidad Autónoma de Bucaramanga, Santander, Colombia; University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy; Medical University of Vienna, Vienna, Austria; Hospital Arzobispo Loayza, Universidad Peruana Cayetano Heredia, Lima, Peru; The University of Texas MD Anderson Cancer Center, Houston, Texas; Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia; CARE Hospitals, Maharanipeta, Visakhapatnam, India; Auckland City Hospital, Auckland, New Zealand; McGill University Health Centre, Montréal, Québec, Canada; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Universitario Fundación Hospital Alcorcon, Madrid, Spain; and Centre Hospitalier Universitaire de Hautepierre, Strasbourg, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>From University of Alberta and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Cleveland Clinic, Cleveland, Ohio; Queen's University, Kingston, Ontario, Canada; Groote Schuur Hospital and University of Cape Town, Western Cape, South Africa; Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada; Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, and Monash University, Melbourne, Victoria, Australia; The Chinese University of Hong Kong, Hong Kong, China; Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; St. John's Medical College and Research Institute, Bangalore, India; Narayana Hrudayalaya, Bangalore, India; University of North Carolina, Chapel Hill, North Carolina; Schulich School of Medicine & Dentistry at Western University, London, Ontario, Canada; Sant Pau Hospital and Biomedical Research Institute, Autonomous University of Barcelona, Research Center of Cardiovascular Diseases (CIBERCV), Barcelona, Spain; Fundación Cardioinfantil Instituto de Cardiología, Bogotá, and Universidad Autónoma de Bucaramanga, Santander, Colombia; University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy; Medical University of Vienna, Vienna, Austria; Hospital Arzobispo Loayza, Universidad Peruana Cayetano Heredia, Lima, Peru; The University of Texas MD Anderson Cancer Center, Houston, Texas; Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia; CARE Hospitals, Maharanipeta, Visakhapatnam, India; Auckland City Hospital, Auckland, New Zealand; McGill University Health Centre, Montréal, Québec, Canada; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Universitario Fundación Hospital Alcorcon, Madrid, Spain; and Centre Hospitalier Universitaire de Hautepierre, Strasbourg</wicri:regionArea><placeName><region type="region">Grand Est</region><region type="old region">Alsace (région administrative)</region><settlement type="city">Strasbourg</settlement></placeName></affiliation></author><author><name sortKey="Devereaux, P J" sort="Devereaux, P J" uniqKey="Devereaux P" first="P J" last="Devereaux">P J Devereaux</name><affiliation wicri:level="3"><nlm:affiliation>From University of Alberta and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Cleveland Clinic, Cleveland, Ohio; Queen's University, Kingston, Ontario, Canada; Groote Schuur Hospital and University of Cape Town, Western Cape, South Africa; Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada; Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, and Monash University, Melbourne, Victoria, Australia; The Chinese University of Hong Kong, Hong Kong, China; Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; St. John's Medical College and Research Institute, Bangalore, India; Narayana Hrudayalaya, Bangalore, India; University of North Carolina, Chapel Hill, North Carolina; Schulich School of Medicine & Dentistry at Western University, London, Ontario, Canada; Sant Pau Hospital and Biomedical Research Institute, Autonomous University of Barcelona, Research Center of Cardiovascular Diseases (CIBERCV), Barcelona, Spain; Fundación Cardioinfantil Instituto de Cardiología, Bogotá, and Universidad Autónoma de Bucaramanga, Santander, Colombia; University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy; Medical University of Vienna, Vienna, Austria; Hospital Arzobispo Loayza, Universidad Peruana Cayetano Heredia, Lima, Peru; The University of Texas MD Anderson Cancer Center, Houston, Texas; Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia; CARE Hospitals, Maharanipeta, Visakhapatnam, India; Auckland City Hospital, Auckland, New Zealand; McGill University Health Centre, Montréal, Québec, Canada; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Universitario Fundación Hospital Alcorcon, Madrid, Spain; and Centre Hospitalier Universitaire de Hautepierre, Strasbourg, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>From University of Alberta and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Cleveland Clinic, Cleveland, Ohio; Queen's University, Kingston, Ontario, Canada; Groote Schuur Hospital and University of Cape Town, Western Cape, South Africa; Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada; Royal Melbourne Hospital, Melbourne Medical School, University of Melbourne, and Monash University, Melbourne, Victoria, Australia; The Chinese University of Hong Kong, Hong Kong, China; Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark; St. John's Medical College and Research Institute, Bangalore, India; Narayana Hrudayalaya, Bangalore, India; University of North Carolina, Chapel Hill, North Carolina; Schulich School of Medicine & Dentistry at Western University, London, Ontario, Canada; Sant Pau Hospital and Biomedical Research Institute, Autonomous University of Barcelona, Research Center of Cardiovascular Diseases (CIBERCV), Barcelona, Spain; Fundación Cardioinfantil Instituto de Cardiología, Bogotá, and Universidad Autónoma de Bucaramanga, Santander, Colombia; University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia; IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy; Medical University of Vienna, Vienna, Austria; Hospital Arzobispo Loayza, Universidad Peruana Cayetano Heredia, Lima, Peru; The University of Texas MD Anderson Cancer Center, Houston, Texas; Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia; CARE Hospitals, Maharanipeta, Visakhapatnam, India; Auckland City Hospital, Auckland, New Zealand; McGill University Health Centre, Montréal, Québec, Canada; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Universitario Fundación Hospital Alcorcon, Madrid, Spain; and Centre Hospitalier Universitaire de Hautepierre, Strasbourg</wicri:regionArea><placeName><region type="region">Grand Est</region><region type="old region">Alsace (région administrative)</region><settlement type="city">Strasbourg</settlement></placeName></affiliation></author></analytic><series><title level="j">Annals of internal medicine</title><idno type="eISSN">1539-3704</idno><imprint><date when="2017" type="published">2017</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Uncertainty remains about the effects of aspirin in patients with prior percutaneous coronary intervention (PCI) having noncardiac surgery.</div></front></TEI><affiliations><list><country><li>France</li></country><region><li>Alsace (région administrative)</li><li>Grand Est</li></region><settlement><li>Strasbourg</li></settlement></list><tree><country name="France"><region name="Grand Est"><name sortKey="Graham, Michelle M" sort="Graham, Michelle M" uniqKey="Graham M" first="Michelle M" last="Graham">Michelle M. Graham</name></region><name sortKey="Alvarez Garcia, Jesus" sort="Alvarez Garcia, Jesus" uniqKey="Alvarez Garcia J" first="Jesus" last="Alvarez-Garcia">Jesus Alvarez-Garcia</name><name sortKey="Aphang Lam, Meylin" sort="Aphang Lam, Meylin" uniqKey="Aphang Lam M" first="Meylin" last="Aphang-Lam">Meylin Aphang-Lam</name><name sortKey="Bessissow, Amal" sort="Bessissow, Amal" uniqKey="Bessissow A" first="Amal" last="Bessissow">Amal Bessissow</name><name sortKey="Biccard, Bruce M" sort="Biccard, Bruce M" uniqKey="Biccard B" first="Bruce M" last="Biccard">Bruce M. Biccard</name><name sortKey="Cata, Juan P" sort="Cata, Juan P" uniqKey="Cata J" first="Juan P" last="Cata">Juan P. Cata</name><name sortKey="Chan, Matthew T V" sort="Chan, Matthew T V" uniqKey="Chan M" first="Matthew T V" last="Chan">Matthew T V. Chan</name><name sortKey="Cook, Deborah J" sort="Cook, Deborah J" uniqKey="Cook D" first="Deborah J" last="Cook">Deborah J. Cook</name><name sortKey="Devereaux, P J" sort="Devereaux, P J" uniqKey="Devereaux P" first="P J" last="Devereaux">P J Devereaux</name><name sortKey="Diemunsch, Pierre A" sort="Diemunsch, Pierre A" uniqKey="Diemunsch P" first="Pierre A" last="Diemunsch">Pierre A. Diemunsch</name><name sortKey="Fleischmann, Edith" sort="Fleischmann, Edith" uniqKey="Fleischmann E" first="Edith" last="Fleischmann">Edith Fleischmann</name><name sortKey="Gao, Peggy" sort="Gao, Peggy" uniqKey="Gao P" first="Peggy" last="Gao">Peggy Gao</name><name sortKey="Guyatt, Gordon" sort="Guyatt, Gordon" uniqKey="Guyatt G" first="Gordon" last="Guyatt">Gordon Guyatt</name><name sortKey="Jamieson, Kim A" sort="Jamieson, Kim A" uniqKey="Jamieson K" first="Kim A" last="Jamieson">Kim A. Jamieson</name><name sortKey="Kumar, Priya A" sort="Kumar, Priya A" uniqKey="Kumar P" first="Priya A" last="Kumar">Priya A. Kumar</name><name sortKey="Lamy, Andre" sort="Lamy, Andre" uniqKey="Lamy A" first="Andre" last="Lamy">Andre Lamy</name><name sortKey="Landoni, Giovanni" sort="Landoni, Giovanni" uniqKey="Landoni G" first="Giovanni" last="Landoni">Giovanni Landoni</name><name sortKey="Le Manach, Yannick" sort="Le Manach, Yannick" uniqKey="Le Manach Y" first="Yannick" last="Le Manach">Yannick Le Manach</name><name sortKey="Leslie, Kate" sort="Leslie, Kate" uniqKey="Leslie K" first="Kate" last="Leslie">Kate Leslie</name><name sortKey="Mendoza, Gabriela R" sort="Mendoza, Gabriela R" uniqKey="Mendoza G" first="Gabriela R" last="Mendoza">Gabriela R. Mendoza</name><name sortKey="Meyhoff, Christian S" sort="Meyhoff, Christian S" uniqKey="Meyhoff C" first="Christian S" last="Meyhoff">Christian S. Meyhoff</name><name sortKey="Mrkobrada, Marko" sort="Mrkobrada, Marko" uniqKey="Mrkobrada M" first="Marko" last="Mrkobrada">Marko Mrkobrada</name><name sortKey="Painter, Thomas W" sort="Painter, Thomas W" uniqKey="Painter T" first="Thomas W" last="Painter">Thomas W. Painter</name><name sortKey="Parlow, Joel L" sort="Parlow, Joel L" uniqKey="Parlow J" first="Joel L" last="Parlow">Joel L. Parlow</name><name sortKey="Ramana, Pamidimukkala V" sort="Ramana, Pamidimukkala V" uniqKey="Ramana P" first="Pamidimukkala V" last="Ramana">Pamidimukkala V. Ramana</name><name sortKey="Ramirez, Silvia" sort="Ramirez, Silvia" uniqKey="Ramirez S" first="Silvia" last="Ramirez">Silvia Ramirez</name><name sortKey="Sessler, Daniel I" sort="Sessler, Daniel I" uniqKey="Sessler D" first="Daniel I" last="Sessler">Daniel I. Sessler</name><name sortKey="Sigamani, Alben" sort="Sigamani, Alben" uniqKey="Sigamani A" first="Alben" last="Sigamani">Alben Sigamani</name><name sortKey="Tandon, Vikas" sort="Tandon, Vikas" uniqKey="Tandon V" first="Vikas" last="Tandon">Vikas Tandon</name><name sortKey="Terblanche, Nicolaas C S" sort="Terblanche, Nicolaas C S" uniqKey="Terblanche N" first="Nicolaas C S" last="Terblanche">Nicolaas C S. Terblanche</name><name sortKey="Villar, Juan Carlos" sort="Villar, Juan Carlos" uniqKey="Villar J" first="Juan Carlos" last="Villar">Juan Carlos Villar</name><name sortKey="Whitlock, Richard" sort="Whitlock, Richard" uniqKey="Whitlock R" first="Richard" last="Whitlock">Richard Whitlock</name><name sortKey="Xavier, Denis" sort="Xavier, Denis" uniqKey="Xavier D" first="Denis" last="Xavier">Denis Xavier</name><name sortKey="Yusuf, Salim" sort="Yusuf, Salim" uniqKey="Yusuf S" first="Salim" last="Yusuf">Salim Yusuf</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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